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Active pharmaceutical ingredient

Atorvastatin Calcium

Atorvastatin Calcium is a widely used active pharmaceutical ingredient known for its efficacy in managing cholesterol levels and reducing the risk of cardiovascular diseases.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Atorvastatin Calcium is a widely utilized active pharmaceutical ingredient known for its efficacy in managing cholesterol levels and reducing cardiovascular risk. As a member of the statin class of medications, Atorvastatin Calcium functions by inhibiting HMG-CoA reductase, an enzyme pivotal in the biosynthesis of cholesterol in the liver. This mechanism effectively lowers low-density lipoprotein (LDL) cholesterol and triglycerides while modestly increasing high-density lipoprotein (HDL) cholesterol, contributing to improved lipid profiles in patients.

In clinical practice, Atorvastatin Calcium is often prescribed for patients with hyperlipidemia, mixed dyslipidemia, and for the prevention of cardiovascular events in individuals with established heart disease or at high risk. Its pharmacokinetic properties, including a long half-life and hepatic metabolism primarily via the cytochrome P450 3A4 pathway, make it a suitable candidate for once-daily dosing, enhancing patient adherence. Additionally, Atorvastatin Calcium has been studied for its pleiotropic effects, which may include anti-inflammatory and plaque-stabilizing properties, further supporting its role in cardiovascular risk management.

When considering Atorvastatin Calcium for compounded formulations, it is essential to account for its physicochemical characteristics, such as solubility and stability, to ensure optimal therapeutic outcomes. Prescribers should also be aware of potential drug-drug interactions, particularly with medications that share the CYP3A4 metabolic pathway, to mitigate adverse effects and maximize efficacy. Regular monitoring of liver function tests and lipid panels is recommended to tailor therapy and ensure safety in long-term use.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.