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Cinacalcet is a calcimimetic agent that plays a crucial role in managing conditions associated with elevated parathyroid hormone levels, such as secondary hyperparathyroidism in patients with chronic kidney.
Cinacalcet is a calcimimetic agent primarily used to manage conditions associated with elevated parathyroid hormone levels, such as secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, and hypercalcemia in patients with parathyroid carcinoma. By increasing the sensitivity of calcium-sensing receptors on the parathyroid gland, Cinacalcet effectively reduces parathyroid hormone (PTH) levels, thereby helping to maintain calcium and phosphorus homeostasis.
This mechanism of action makes Cinacalcet a valuable therapeutic option for patients who require precise control over their calcium and PTH levels, especially when traditional treatments are insufficient. The pharmacokinetics of Cinacalcet involve rapid absorption with peak plasma concentrations typically reached within 2 to 6 hours post-administration, and it is extensively metabolized in the liver, primarily via CYP3A4 and CYP1A2 pathways.
Due to its potent effects, careful monitoring of serum calcium and PTH levels is recommended during treatment to avoid potential complications such as hypocalcemia. Cinacalcet is generally well-tolerated, but some patients may experience side effects including nausea, vomiting, and dizziness, which should be managed under the guidance of a healthcare professional.
In the context of compounded formulations, Cinacalcet can be tailored to meet specific patient needs, offering flexibility in dosing and administration that may not be available with commercially available products. This customization is particularly beneficial for patients with unique therapeutic requirements or those who experience difficulty with standard dosage forms.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
