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Active pharmaceutical ingredient

Clomiphene Citrate

Clomiphene Citrate is a selective estrogen receptor modulator (SERM) commonly used in fertility treatments to stimulate ovulation in women who experience ovulatory dysfunction.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Clomiphene Citrate is a well-established active pharmaceutical ingredient primarily used in the treatment of infertility in women. It functions as a selective estrogen receptor modulator (SERM), which means it can either block or activate estrogen receptors in different tissues. This dual action is crucial in stimulating ovulation, making Clomiphene Citrate a first-line treatment for women experiencing ovulatory dysfunction.

By binding to estrogen receptors in the hypothalamus, Clomiphene Citrate effectively tricks the body into perceiving lower estrogen levels. This perceived deficiency prompts the pituitary gland to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are essential for the growth and maturation of ovarian follicles. The increased levels of these hormones enhance the likelihood of ovulation, thereby improving the chances of conception.

Clomiphene Citrate is typically administered orally, and its dosage is carefully tailored to the patient's specific needs and response to treatment. It is crucial for healthcare providers to monitor patients closely, as the medication can lead to multiple pregnancies and other side effects such as ovarian hyperstimulation syndrome (OHSS). Despite these potential risks, Clomiphene Citrate remains a cornerstone in fertility treatments due to its efficacy and relatively favorable safety profile.

In addition to its primary use in female infertility, Clomiphene Citrate has also been explored for off-label uses, including the treatment of male infertility and certain cases of hypogonadism. Its ability to modulate hormonal pathways makes it a versatile tool in reproductive medicine. However, such applications should be approached with caution and under the guidance of a healthcare professional, as the evidence supporting these uses is still evolving.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.