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Active pharmaceutical ingredient

Clopidogrel Bisulfate

Clopidogrel Bisulfate is a potent antiplatelet agent commonly used to prevent blood clots in patients with cardiovascular conditions.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Clopidogrel Bisulfate is a potent antiplatelet agent widely used in the prevention of thrombotic cardiovascular events. It functions by inhibiting the P2Y12 component of ADP receptors on the platelet surface, which prevents platelet activation and aggregation, crucial in reducing the risk of stroke, myocardial infarction, and other cardiovascular complications.

As a prodrug, Clopidogrel Bisulfate requires metabolic activation primarily by the liver enzyme CYP2C19 to produce its active metabolite. This metabolic pathway can be influenced by genetic variations, which may affect the drug's efficacy and safety profile. Therefore, understanding a patient's genetic makeup can be essential in optimizing Clopidogrel therapy.

Clopidogrel Bisulfate is often prescribed in combination with aspirin for dual antiplatelet therapy, especially in patients undergoing percutaneous coronary intervention (PCI) or those with acute coronary syndrome (ACS). This combination enhances the antithrombotic effect, providing a comprehensive approach to managing cardiovascular risks.

In clinical practice, the dosing of Clopidogrel Bisulfate may vary based on the specific condition being treated, patient response, and potential drug interactions. It is crucial for healthcare providers to consider these factors to ensure optimal therapeutic outcomes while minimizing adverse effects.

Common side effects associated with Clopidogrel Bisulfate include bleeding, bruising, and gastrointestinal disturbances. Prescribers should monitor patients for signs of bleeding and counsel them on recognizing symptoms that warrant immediate medical attention.

Given its significant role in cardiovascular disease management, Clopidogrel Bisulfate remains a cornerstone in antiplatelet therapy. Its use in compounded formulations allows for tailored dosing and delivery methods, enhancing patient adherence and therapeutic efficacy.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.