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Active pharmaceutical ingredient

Clorazepate dipotassium

Clorazepate dipotassium is a benzodiazepine derivative commonly utilized in the management of anxiety disorders, seizure disorders, and alcohol withdrawal symptoms.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Clorazepate dipotassium is a benzodiazepine derivative that is commonly utilized in the management of anxiety disorders, seizure disorders, and alcohol withdrawal symptoms. As a prodrug, it is metabolized into its active form, nordiazepam, which exerts its therapeutic effects by enhancing the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system. This action results in a calming effect on the brain, making it effective for reducing anxiety and preventing seizures.

Due to its pharmacokinetic properties, clorazepate dipotassium is often preferred for its relatively long half-life, which allows for less frequent dosing and can improve patient compliance. It is important for prescribers to consider the potential for tolerance, dependence, and withdrawal symptoms associated with long-term use of benzodiazepines. Therefore, clorazepate dipotassium should be prescribed with caution, particularly in patients with a history of substance abuse or in those who may be at risk for developing dependence.

In the context of compounding, clorazepate dipotassium can be formulated into various dosage forms to meet specific patient needs, such as those requiring alternative routes of administration or tailored dosing regimens. This flexibility is particularly beneficial for patients who may have difficulty swallowing tablets or require a more individualized approach to their medication therapy. Prescribers should work closely with compounding pharmacists to ensure that formulations are both safe and effective for their patients.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.