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Active pharmaceutical ingredient

Efavirenz

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) widely used in the management of HIV-1 infection.

Compounded to order
Prescription required

About this ingredient

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) widely used in the treatment of HIV-1 infection. It functions by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus, thereby reducing viral load and improving immune function in patients.

Efavirenz is often included in antiretroviral therapy regimens due to its efficacy and once-daily dosing convenience. It is metabolized primarily by the liver, with cytochrome P450 enzymes playing a significant role in its biotransformation, which necessitates careful consideration of potential drug interactions.

Common side effects associated with Efavirenz include central nervous system symptoms such as dizziness, insomnia, and vivid dreams, which may diminish over time. Prescribers should monitor patients for these effects and consider dose adjustments or alternative therapies if necessary.

Efavirenz is contraindicated in patients with known hypersensitivity to the drug or any of its components. It is also advised to avoid use during pregnancy, particularly in the first trimester, due to potential teratogenic effects.

When prescribing Efavirenz, it is essential to consider the patient's overall antiretroviral regimen, potential drug-drug interactions, and individual patient factors such as liver function and pregnancy status. Regular monitoring and patient education on adherence and side effect management are crucial for optimizing treatment outcomes.

Compounded at Bayview

How we prepare this ingredient

Patient guides for the preparations we make most often. Each one is compounded to order and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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For prescribers

Full formulary with this ingredient

Every preparation in our formulary that contains this ingredient. Strength, base and dose form are set by the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.