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Imatinib is a potent tyrosine kinase inhibitor primarily used in the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs).
Imatinib is a potent tyrosine kinase inhibitor primarily used in the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). By targeting specific proteins involved in cancer cell proliferation, Imatinib effectively disrupts the signaling pathways that promote tumor growth and survival.
This API is particularly valuable in personalized medicine, as it allows for targeted therapy that minimizes damage to healthy cells, thereby reducing the side effects commonly associated with traditional chemotherapy. Imatinib's mechanism of action involves the inhibition of the BCR-ABL tyrosine kinase, a fusion protein that results from a chromosomal abnormality in CML patients.
Additionally, Imatinib is known to inhibit other tyrosine kinases such as c-KIT and PDGFR, which are implicated in various malignancies. Its efficacy and safety profile have been well-documented, making it a cornerstone in the management of specific cancers.
Prescribers should be aware of potential drug interactions and the need for regular monitoring of blood counts and liver function tests during treatment. The pharmacokinetics of Imatinib indicate that it is metabolized primarily in the liver, and dose adjustments may be necessary for patients with hepatic impairment.
Overall, Imatinib represents a significant advancement in cancer therapy, offering a targeted approach that aligns with the principles of precision medicine. Its use in compounded formulations allows for tailored dosing regimens that can meet the unique needs of individual patients, enhancing therapeutic outcomes.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
