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Active pharmaceutical ingredient

Lamotrigine

Lamotrigine is a widely utilized active pharmaceutical ingredient known for its efficacy in managing seizure disorders and bipolar disorder.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Lamotrigine is a well-established active pharmaceutical ingredient primarily used in the management of epilepsy and bipolar disorder. It functions as an anticonvulsant and mood stabilizer, effectively reducing the frequency and severity of seizures and mood swings. By inhibiting voltage-sensitive sodium channels, lamotrigine stabilizes neuronal membranes and modulates neurotransmitter release, which is crucial in controlling epileptic episodes and mood fluctuations.

In the context of epilepsy, lamotrigine is often prescribed for partial seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Its efficacy in treating bipolar disorder, particularly in delaying the time to occurrence of mood episodes, makes it a valuable option for long-term management. The pharmacokinetics of lamotrigine involve rapid absorption with a bioavailability of approximately 98%, and it is metabolized primarily in the liver through glucuronidation.

Lamotrigine's safety profile is generally favorable, though it requires careful titration to minimize the risk of adverse effects such as skin rashes, which can be severe. It is crucial for prescribers to monitor patients closely during the initial phases of treatment and adjust dosages based on therapeutic response and tolerability. The versatility of lamotrigine in various formulations allows for tailored dosing regimens, enhancing patient adherence and therapeutic outcomes.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.