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Mupirocin Calcium is a potent antibacterial agent primarily used in topical formulations to treat skin infections caused by susceptible strains of bacteria, including Staphylococcus aureus and Streptococcus.
Mupirocin Calcium is a potent antibacterial agent primarily used in topical formulations to treat skin infections caused by susceptible strains of bacteria. It is particularly effective against Staphylococcus aureus, including methicillin-resistant strains (MRSA), and Streptococcus pyogenes, making it a valuable option in managing bacterial skin infections.
This API works by inhibiting bacterial protein synthesis, specifically targeting the isoleucyl-tRNA synthetase enzyme, which is crucial for bacterial growth and replication. Due to its unique mechanism of action, mupirocin calcium is less likely to cause cross-resistance with other antibiotics, preserving its efficacy in treating resistant bacterial strains.
In clinical settings, mupirocin calcium is often prescribed for the treatment of impetigo, folliculitis, and other minor skin infections. Its use is also extended to the eradication of nasal carriage of MRSA, helping to prevent the spread of this resistant bacterium in healthcare environments.
When formulating with mupirocin calcium, it is essential to consider its stability and compatibility with other excipients to ensure optimal therapeutic outcomes. The API is typically incorporated into ointments or creams, providing a localized effect with minimal systemic absorption, which reduces the risk of systemic side effects.
Healthcare providers should be aware of the potential for local irritation or allergic reactions, although these are generally rare. Monitoring for signs of superinfection with non-susceptible organisms is also recommended during prolonged use.
Overall, mupirocin calcium remains a critical component in the arsenal against bacterial skin infections, offering targeted action with a favorable safety profile. Its role in both treatment and prevention of infections underscores its importance in clinical practice.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
