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Nifedipine Hydrochloride is a potent calcium channel blocker primarily used to manage hypertension and angina pectoris.
Nifedipine Hydrochloride is a potent calcium channel blocker widely utilized in the management of cardiovascular conditions, particularly hypertension and angina pectoris. By inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, it effectively reduces peripheral vascular resistance and myocardial oxygen demand, leading to vasodilation and decreased blood pressure.
This API is particularly beneficial in patients with chronic stable angina, as it helps alleviate chest pain by improving coronary blood flow. Additionally, Nifedipine Hydrochloride is often employed in the treatment of Raynaud's phenomenon, where it aids in reducing the frequency and severity of vasospastic attacks.
Its pharmacokinetic profile allows for both immediate and extended-release formulations, providing flexibility in tailoring treatment regimens to individual patient needs. The extended-release formulations are especially advantageous for maintaining consistent therapeutic levels, thereby enhancing patient compliance and minimizing the risk of adverse effects.
Prescribers should be aware of potential interactions with other medications, such as beta-blockers, which may potentiate the hypotensive effects of Nifedipine Hydrochloride. Monitoring for side effects like dizziness, flushing, and peripheral edema is crucial, as these are common but manageable with appropriate dose adjustments.
In the context of compounding, Nifedipine Hydrochloride offers versatility, allowing for customized dosage forms that can address specific patient requirements, such as those with swallowing difficulties or requiring alternative routes of administration. This adaptability underscores its value in personalized medicine, ensuring optimal therapeutic outcomes for diverse patient populations.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
It is a compounded, prescription medication applied to the anal area. Nifedipine is a calcium channel blocker, and used this way it relaxes the ring of muscle around the anus. Providers most often prescribe it for anal fissures, small tears in the skin of the anal canal that cause sharp pain and bleeding with bowel movements. Bayview compounds it at 0.3% strength as an ointment.
They are the two calcium channel blockers commonly compounded for fissures, and they work the same way: relaxing the anal sphincter so the tear can heal. The strengths differ (0.3% for nifedipine, 2% for diltiazem) because of how each drug is typically used, not because one is stronger in effect. Your provider chooses between them based on your history and their experience.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
