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Norfloxacin is a synthetic fluoroquinolone antibiotic that is widely utilized for its broad-spectrum antibacterial properties.
Norfloxacin is a synthetic fluoroquinolone antibiotic that is widely utilized in the treatment of various bacterial infections. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication, transcription, repair, and recombination, thereby preventing bacterial cell division and growth.
This API is particularly effective against a broad spectrum of Gram-negative and some Gram-positive bacteria, making it a versatile choice for treating infections such as urinary tract infections, prostatitis, and certain types of gastroenteritis. Norfloxacin's pharmacokinetic profile includes good oral absorption, although its bioavailability can be affected by the presence of food or antacids containing magnesium or aluminum.
Prescribers should be aware of potential side effects, which may include gastrointestinal disturbances, CNS effects like dizziness or headache, and hypersensitivity reactions. It is crucial to consider patient-specific factors such as renal function, as dosage adjustments may be necessary in cases of renal impairment.
Additionally, norfloxacin should be used with caution in patients with a history of tendon disorders related to fluoroquinolone use, and it is generally not recommended for use in children or pregnant women due to potential adverse effects on developing cartilage. As antibiotic resistance continues to be a significant concern, norfloxacin should be prescribed judiciously, ensuring it is the most appropriate choice based on culture and sensitivity results when available.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
