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Active pharmaceutical ingredient

Sulfadiazine Sodium

Sulfadiazine Sodium is a sulfonamide antibiotic widely utilized in compounded formulations for its potent antibacterial properties.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Sulfadiazine Sodium is a potent antibacterial agent belonging to the sulfonamide class, widely utilized in compounded formulations for its broad-spectrum antimicrobial properties. It functions by inhibiting bacterial synthesis of dihydrofolic acid, a critical component in the production of nucleic acids and proteins, thereby impeding bacterial growth and proliferation. This mechanism makes it particularly effective against a variety of gram-positive and gram-negative bacteria, offering a versatile option for treating infections.

In clinical settings, Sulfadiazine Sodium is often prescribed for its efficacy in managing urinary tract infections, respiratory tract infections, and certain types of meningitis. Its ability to penetrate tissues and fluids, including the cerebrospinal fluid, enhances its therapeutic potential in treating systemic infections. Additionally, it is frequently used in combination with other antibiotics to enhance antimicrobial coverage and reduce the risk of resistance development.

Prescribers should be aware of potential hypersensitivity reactions associated with sulfonamides, and it is contraindicated in patients with a known allergy to sulfa drugs. Monitoring for signs of hematological changes, such as leukopenia or thrombocytopenia, is recommended during prolonged therapy. Adequate hydration is advised to prevent crystalluria and renal complications, ensuring optimal patient outcomes.

Given its pharmacokinetic profile, Sulfadiazine Sodium is well-absorbed orally, with a rapid onset of action, making it a reliable choice for acute infection management. Its excretion primarily through the kidneys necessitates dose adjustments in patients with renal impairment to avoid accumulation and toxicity. Overall, Sulfadiazine Sodium remains a valuable component in the arsenal of antimicrobial agents, offering flexibility and efficacy in tailored therapeutic regimens.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.