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Active pharmaceutical ingredient

Tizanidine Hydrochloride

Tizanidine Hydrochloride is a centrally acting alpha-2 adrenergic agonist primarily used as a muscle relaxant to manage spasticity.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Tizanidine Hydrochloride is a centrally acting alpha-2 adrenergic agonist primarily used as a muscle relaxant to manage spasticity. It functions by inhibiting presynaptic motor neurons, thereby reducing muscle tone and alleviating muscle spasms, which can be particularly beneficial for patients with conditions such as multiple sclerosis or spinal cord injuries.

Due to its mechanism of action, Tizanidine Hydrochloride is often preferred for its relatively short duration of effect, allowing for more controlled management of muscle spasticity. This characteristic makes it suitable for patients who require intermittent relief from muscle stiffness without prolonged sedation or muscle weakness.

In compounded formulations, Tizanidine Hydrochloride can be tailored to meet specific patient needs, offering flexibility in dosing and administration routes. This customization is crucial for patients who may have difficulty swallowing tablets or require a specific dosage that is not commercially available.

Prescribers should be aware of potential side effects, including drowsiness, dizziness, and dry mouth, which are common with Tizanidine Hydrochloride. It is also important to consider potential interactions with other medications, particularly those that affect the cytochrome P450 enzyme system, as these can alter the drug's metabolism and efficacy.

When prescribing Tizanidine Hydrochloride, careful titration is recommended to minimize adverse effects while achieving optimal therapeutic outcomes. Monitoring liver function is also advised, as the drug can affect hepatic enzymes, especially in patients with pre-existing liver conditions.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.