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Active pharmaceutical ingredient

Trimeprazine

Trimeprazine is a potent antihistamine with sedative properties, commonly utilized in compounded formulations to manage allergic reactions and pruritus.

Compounded to order
Prescription required

About this ingredient

Trimeprazine, also known as alimemazine, is a phenothiazine derivative with antihistaminic and sedative properties, commonly utilized in compounded formulations for its efficacy in managing allergic reactions and pruritus. Its mechanism of action primarily involves the blockade of histamine H1 receptors, which helps alleviate symptoms associated with allergic conditions such as itching, sneezing, and runny nose.

In addition to its antihistaminic effects, Trimeprazine exhibits sedative qualities, making it beneficial in formulations aimed at providing relief from anxiety and promoting sleep in patients experiencing discomfort due to allergies. This dual action makes it a versatile component in personalized medicine, allowing healthcare providers to tailor treatments to individual patient needs.

Trimeprazine's pharmacokinetic profile includes rapid absorption and a moderate half-life, which supports its use in formulations requiring sustained symptom control. Its safety and efficacy have been well-documented, although prescribers should be mindful of potential side effects such as drowsiness, dry mouth, and, in rare cases, extrapyramidal symptoms.

When considering Trimeprazine for compounding, it is essential to evaluate the patient's overall medication regimen to avoid interactions, particularly with other central nervous system depressants. By understanding the unique properties and applications of Trimeprazine, healthcare professionals can effectively incorporate it into treatment plans to enhance patient outcomes in managing allergic and anxiety-related conditions.

Compounded at Bayview

How we prepare this ingredient

Patient guides for the preparations we make most often. Each one is compounded to order and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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For prescribers

Full formulary with this ingredient

Every preparation in our formulary that contains this ingredient. Strength, base and dose form are set by the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.