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Active pharmaceutical ingredient

Valsartan

Valsartan is a potent angiotensin II receptor blocker (ARB) commonly used in the management of hypertension and heart failure.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Valsartan is a potent angiotensin II receptor blocker (ARB) widely used in the management of hypertension and heart failure. By selectively inhibiting the binding of angiotensin II to the AT1 receptor, valsartan effectively reduces vasoconstriction, aldosterone secretion, and sodium retention, leading to decreased blood pressure and improved cardiovascular outcomes.

Its pharmacokinetic profile is characterized by rapid absorption with peak plasma concentrations typically reached within 2 to 4 hours post-administration. Valsartan is primarily excreted unchanged in the bile, with a half-life of approximately 6 hours, making it suitable for once-daily dosing in most patients.

Clinical studies have demonstrated valsartan's efficacy in reducing the risk of cardiovascular events, particularly in patients with left ventricular dysfunction post-myocardial infarction. It is also beneficial in slowing the progression of renal disease in patients with type 2 diabetes and hypertension.

Valsartan is generally well-tolerated, with a side effect profile that includes dizziness, hyperkalemia, and renal function impairment, particularly in patients with pre-existing renal conditions. It is contraindicated in pregnancy due to the risk of fetal harm.

When considering valsartan for therapeutic use, it is crucial to evaluate patient-specific factors such as concurrent medications, renal function, and potential drug interactions. This ensures optimal dosing and minimizes adverse effects, enhancing patient outcomes in the management of cardiovascular conditions.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.