Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Acetaminophen 300 mg Rectal Suppository

The Acetaminophen 300 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the medication for local or systemic absorption. This formulation of Acetaminophen is typically used to treat conditions such as pain and fever, providing relief by reducing the body's production of prostaglandins, which are chemicals that cause inflammation and trigger pain signals.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Are you a prescriber? Sign Up
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Suppository
652f1c8ac61afda2bd78ec54
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

The Acetaminophen 300 mg Rectal Suppository is a specialized formulation designed for rectal administration. This solid dosage form is inserted into the rectum, where it dissolves or melts to release the medication. The primary active ingredient, Acetaminophen, is then absorbed locally or systemically to exert its therapeutic effects.

Acetaminophen is a well-known analgesic (pain reliever) and antipyretic (fever reducer). It works by changing the way the body senses pain and by cooling the body. This makes it an effective treatment for various disease states that involve pain and/or fever. These include conditions like headaches, muscle aches, arthritis, backache, toothaches, colds, and fevers. It can also be used post-surgery or in other clinical situations where oral administration is not possible or desirable.

Rectal administration of Acetaminophen has several advantages. It can be used in patients who have difficulty swallowing, are nauseous, vomiting, or unconscious. It also bypasses the first-pass metabolism in the liver, which can lead to a more rapid and efficient absorption of the drug. This can result in quicker relief of symptoms.

However, it's important to note that like all medications, Acetaminophen can cause side effects. These may include constipation, gas, or irritation where the suppository was inserted. Serious side effects are rare but can include a severe allergic reaction. Always inform your healthcare provider of any unusual or bothersome side effects.

As compounding pharmacists, we can customize the dose of Acetaminophen in the suppository to meet individual patient needs. This can be particularly beneficial for pediatric or geriatric patients, or those with unique dosage requirements. We can also add other medications to the suppository if needed, to treat additional symptoms or conditions.

It's crucial to use this medication as directed by your healthcare provider. Do not exceed the recommended dose or frequency of administration. Overdose of Acetaminophen can lead to serious liver damage. If you have any questions about this formulation, its use, or if you would like to discuss customizing a medication to meet your specific needs, please reach out to us at Bayview Pharmacy. We are here to help.

Drug Interactions

A small arrow pointing down

Acetaminophen, also known as paracetamol, is a common over-the-counter medication used to relieve pain and reduce fever. It is available in various forms, including oral tablets, liquids, and rectal suppositories. The rectal suppository form is often used when oral administration is not possible or desirable, such as in cases of nausea and vomiting, or in patients who have difficulty swallowing.

While generally safe and effective when used as directed, acetaminophen can interact with certain other medications, potentially altering their effects or increasing the risk of side effects. It is important for patients and prescribers to be aware of these potential interactions.

Acetaminophen may interact with certain anticoagulants, such as warfarin. This interaction can increase the risk of bleeding. If you are taking an anticoagulant, your doctor may need to monitor your blood clotting time more closely while you are using acetaminophen.

Some anticonvulsant medications, such as phenytoin, carbamazepine, and barbiturates, can increase the liver's ability to metabolize acetaminophen, potentially reducing its effectiveness. If you are taking an anticonvulsant, your doctor may need to adjust your dose of acetaminophen or monitor you more closely for signs of pain or fever.

Acetaminophen can also interact with certain antibiotics, such as isoniazid, increasing the risk of liver damage. If you are taking isoniazid, you should use acetaminophen only under the close supervision of your doctor.

Alcohol can increase the risk of liver damage from acetaminophen. If you regularly consume three or more alcoholic drinks per day, you should talk to your doctor before using acetaminophen.

These are not all the possible drug interactions with acetaminophen. It is important to tell your doctor and pharmacist about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, so they can check for any potential interactions.

Acetaminophen rectal suppositories are used to treat mild to moderate pain and to reduce fever. They work by changing the way the body senses pain and by cooling the body. They can be used to treat a variety of conditions, including headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

If you have any questions about acetaminophen rectal suppositories or their potential interactions with other medications, please reach out to us. We are here to help.

How Does it Work

A small arrow pointing down

Acetaminophen 300 mg Rectal Suppository is a solid dosage form that is designed to be inserted into the rectum, where it dissolves or melts to release the medication. The active ingredient in this formulation is Acetaminophen, a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).

Once the suppository is inserted into the rectum, it begins to dissolve due to the body's natural heat. As it dissolves, the Acetaminophen is released and absorbed through the rectal tissue into the bloodstream. This method of administration bypasses the digestive system, which can be beneficial for patients who have difficulty swallowing pills, are vomiting, or for whom oral administration is otherwise contraindicated.

Acetaminophen works by inhibiting the synthesis of prostaglandins, substances in the body that cause pain and inflammation. It also acts on the heat-regulating center of the brain to reduce fever. However, unlike other common analgesics like ibuprofen and aspirin, Acetaminophen does not reduce inflammation.

This formulation can be used to treat various disease states that involve pain and/or fever. These include but are not limited to headaches, muscle aches, arthritis, backache, toothaches, colds, and fevers. It is important to note that while Acetaminophen can help manage these symptoms, it does not treat the underlying cause of the symptoms.

As with any medication, it is crucial to use Acetaminophen as directed by a healthcare provider. Overuse or misuse of Acetaminophen can lead to serious liver damage. If you have any questions about this formulation or its appropriate use, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Other Uses

A small arrow pointing down

Acetaminophen 300 mg Rectal Suppositories are typically formulated to provide systemic relief from moderate to severe pain, fever, or the symptoms of cold and flu. However, beyond its conventional uses, this formulation can also be effective in certain medical situations where oral administration may not be feasible. This drug is commonly used as an analgesic (pain reliever) and an antipyretic (fever reducer). If oral ingestion is not possible, for instance in patients with difficulty swallowing, severe nausea or vomiting, or when oral intake is restricted prior to or after surgical procedures, the rectal route can be an alternative to ensure that the drug is still administered and absorption occurs.

Additionally, acetaminophen suppositories may also be used for pain control in patients who have been placed on medication restrictions pertaining to their upper gastrointestinal system. These might be patients with gastric ulcers or those at risk of bleeding from the stomach. For these patients, a rectal suppository can bypass the stomach and not exacerbate these conditions. Acetaminophen suppositories can also assist in pain management for patients with chronic pain conditions and offer a preferable alternative for those who have trouble with oral medications.

Doctors may also use this formulation, especially for relieving postoperative pain or for controlling fever in hospitalized patients. For those with chronic conditions that might evolve over time, such as those with dementia or cognitive impairment who may resist oral intake, it might be easier to administer medication rectally.

An important point to highlight is that while this formulation offers versatility in the usage of Acetaminophen, it should not be used without appropriate consultation with a healthcare provider. The dose, frequency, and duration of acetaminophen treatment need to conform to individual medical needs and physical conditions, thereby mandating professional advice before initiation of this form of administration.

If you have more questions or require additional guidance on the application of Acetaminophen 300 mg Rectal Suppositories, please reach out to us. Our team of compounding pharmacists at Bayview Pharmacy are always on hand to help.

Frequently Asked Questions

A small arrow pointing down

What is the Acetaminophen 300 mg Rectal Suppository?

This is a solid dosage form of the drug Acetaminophen, designed to be inserted into a body cavity, typically the rectum. Once inserted, it dissolves or melts to release the medication, which can then be absorbed by the body either for local effect or for systemic absorption.

What is this medication used for?

Acetaminophen is used to relieve pain and reduce fever. If you are unsure why you are using this medication, please contact your healthcare provider.

How should this medication be stored?

Store the suppository in a cool, dry place, away from direct sunlight. Keep it out of the reach of children.

How often should I use this product?

The frequency of use of this Acetaminophen rectal suppository will be determined by your healthcare provider, based on your symptoms and condition.

Is this Acetaminophen suppository safe for children?

Yes, it can be used in children but only under the supervision of a healthcare provider. The dosage must be adjusted according to the child's weight and age.

What will happen if I miss a dose?

If you miss a dose, use it as soon as you remember. But if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not use double the dose to make up for the missed one.

Are there any side effects to this medication?

As with any medication, Acetaminophen suppository can cause side effects, although not everyone experiences them. Possible side effects include constipation, dry mouth, and dizziness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I use this product while pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. Your healthcare provider will be able to advise you on the benefits and potential risks associated with the use of this medication during pregnancy or breastfeeding.

How should I dispose of unused suppositories?

If you have unused suppositories, don’t flush them down the toilet. Consult your pharmacist or local waste disposal company about how to properly dispose of them.

Should I use this suppository if I have liver problems?

If you have existing liver problems or disease, it's important to consult your healthcare provider before using Acetaminophen as it may affect your liver function.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.