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Acetaminophen 300 mg Rectal Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Acetaminophen

The Acetaminophen 300 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the medication for local or systemic absorption. This formulation of Acetaminophen is typically used to treat conditions such as pain and fever, providing relief by reducing the body's production of prostaglandins, which are chemicals that cause inflammation and trigger pain signals.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acetaminophen
Suppository
652f1c8ac61afda2bd78ec54
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Acetaminophen 300 mg Rectal Suppository is a specialized formulation designed for rectal administration. This solid dosage form is inserted into the rectum, where it dissolves or melts to release the medication. The primary active ingredient, Acetaminophen, is then absorbed locally or systemically to exert its therapeutic effects.

Acetaminophen is a well-known analgesic (pain reliever) and antipyretic (fever reducer). It works by changing the way the body senses pain and by cooling the body. These include conditions like headaches, muscle aches, arthritis, backache, toothaches, colds, and fevers. It can also be used post-surgery or in other clinical situations where oral administration is not possible or desirable.

Rectal administration of Acetaminophen has several advantages. It can be used in patients who have difficulty swallowing, are nauseous, vomiting, or unconscious. It also bypasses the first-pass metabolism in the liver, which can lead to a more rapid and efficient absorption of the drug. This can result in quicker relief of symptoms.

However, it's important to note that like all medications, Acetaminophen can cause side effects. These may include constipation, gas, or irritation where the suppository was inserted. Serious side effects are rare but can include a severe allergic reaction. Always inform your healthcare provider of any unusual or bothersome side effects.

As compounding pharmacists, we can customize the dose of Acetaminophen in the suppository to meet individual patient needs. This can be particularly beneficial for pediatric or geriatric patients, or those with unique dosage requirements. We can also add other medications to the suppository if needed, to treat additional symptoms or conditions.

It's crucial to use this medication as directed by your healthcare provider. Do not exceed the recommended dose or frequency of administration. Overdose of Acetaminophen can lead to serious liver damage. If you have any questions about this formulation, its use, or if you would like to discuss customizing a medication to meet your specific needs, please reach out to us at Bayview Pharmacy. We are here to help.

Drug Interactions

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Acetaminophen, also known as paracetamol, is a common over-the-counter medication used to relieve pain and reduce fever. It is available in various forms, including oral tablets, liquids, and rectal suppositories. The rectal suppository form is often used when oral administration is not possible or desirable, such as in cases of nausea and vomiting, or in patients who have difficulty swallowing.

It is important for patients and prescribers to be aware of these potential interactions.

Acetaminophen may interact with certain anticoagulants, such as warfarin. This interaction can increase the risk of bleeding. If you are taking an anticoagulant, your doctor may need to monitor your blood clotting time more closely while you are using acetaminophen.

Some anticonvulsant medications, such as phenytoin, carbamazepine, and barbiturates, can increase the liver's ability to metabolize acetaminophen, potentially reducing its effectiveness. If you are taking an anticonvulsant, your doctor may need to adjust your dose of acetaminophen or monitor you more closely for signs of pain or fever.

Acetaminophen can also interact with certain antibiotics, such as isoniazid, increasing the risk of liver damage. If you are taking isoniazid, you should use acetaminophen only under the close supervision of your doctor.

Alcohol can increase the risk of liver damage from acetaminophen. If you regularly consume three or more alcoholic drinks per day, you should talk to your doctor before using acetaminophen.

These are not all the possible drug interactions with acetaminophen. It is important to tell your doctor and pharmacist about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, so they can check for any potential interactions.

Acetaminophen rectal suppositories are used to treat mild to moderate pain and to reduce fever. They work by changing the way the body senses pain and by cooling the body. They can be used to treat a variety of conditions, including headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

If you have any questions about acetaminophen rectal suppositories or their potential interactions with other medications, please reach out to us. We are here to help.

How Does it Work

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Acetaminophen 300 mg Rectal Suppository is a solid dosage form that is designed to be inserted into the rectum, where it dissolves or melts to release the medication. The active ingredient in this formulation is Acetaminophen, a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).

Once the suppository is inserted into the rectum, it begins to dissolve due to the body's natural heat. As it dissolves, the Acetaminophen is released and absorbed through the rectal tissue into the bloodstream. This method of administration bypasses the digestive system, which can be beneficial for patients who have difficulty swallowing pills, are vomiting, or for whom oral administration is otherwise contraindicated.

Acetaminophen works by inhibiting the synthesis of prostaglandins, substances in the body that cause pain and inflammation. It also acts on the heat-regulating center of the brain to reduce fever. However, unlike other common analgesics like ibuprofen and aspirin, Acetaminophen does not reduce inflammation.

This formulation can be used to treat various disease states that involve pain and/or fever. These include but are not limited to headaches, muscle aches, arthritis, backache, toothaches, colds, and fevers. It is important to note that while Acetaminophen can help manage these symptoms, it does not treat the underlying cause of the symptoms.

As with any medication, it is crucial to use Acetaminophen as directed by a healthcare provider. Overuse or misuse of Acetaminophen can lead to serious liver damage. If you have any questions about this formulation or its appropriate use, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Frequently Asked Questions

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What is the Acetaminophen 300 mg Rectal Suppository?

This is a solid dosage form of the drug Acetaminophen, designed to be inserted into a body cavity, typically the rectum. Once inserted, it dissolves or melts to release the medication, which can then be absorbed by the body either for local effect or for systemic absorption.

What is this medication used for?

Acetaminophen is used to relieve pain and reduce fever. If you are unsure why you are using this medication, please contact your healthcare provider.

How should this medication be stored?

Store the suppository in a cool, dry place, away from direct sunlight. Keep it out of the reach of children.

How often should I use this product?

The frequency of use of this Acetaminophen rectal suppository will be determined by your healthcare provider, based on your symptoms and condition.

Is this Acetaminophen suppository safe for children?

Yes, it can be used in children but only under the supervision of a healthcare provider. The dosage must be adjusted according to the child's weight and age.

What will happen if I miss a dose?

If you miss a dose, use it as soon as you remember. But if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not use double the dose to make up for the missed one.

Are there any side effects to this medication?

As with any medication, Acetaminophen suppository can cause side effects, although not everyone experiences them. Possible side effects include constipation, dry mouth, and dizziness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I use this product while pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. Your healthcare provider will be able to advise you on the benefits and potential risks associated with the use of this medication during pregnancy or breastfeeding.

How should I dispose of unused suppositories?

If you have unused suppositories, don’t flush them down the toilet. Consult your pharmacist or local waste disposal company about how to properly dispose of them.

Should I use this suppository if I have liver problems?

If you have existing liver problems or disease, it's important to consult your healthcare provider before using Acetaminophen as it may affect your liver function.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acetaminophen 300 mg Rectal Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

Every 6 hours as needed