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Acyclovir 50 mg/mL/Lidocaine HCl 20 mg/mL Topical Gel is a semisolid formulation designed for the treatment of herpes simplex virus infections, including cold sores and genital herpes. This gel is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures targeted treatment and effective absorption of active ingredients, providing antiviral and analgesic effects to alleviate symptoms and promote healing.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Acyclovir 50 mg/mL/Lidocaine HCl 20 mg/mL Topical Gel is a compounded formulation designed for the treatment of viral skin infections, such as herpes simplex virus (HSV) infections, and to provide localized pain relief. Acyclovir is an antiviral agent that works by inhibiting the replication of viral DNA, thereby reducing the severity and duration of outbreaks. Lidocaine HCl is a local anesthetic that provides pain relief by blocking nerve signals in the body. This combination allows for both antiviral action and symptomatic relief in a single application.
When considering the use of Acyclovir 50 mg/mL/Lidocaine HCl 20 mg/mL Topical Gel, it is important to be aware of potential drug interactions. Although topical formulations generally have a lower risk of systemic interactions compared to oral medications, there are still important considerations. Acyclovir, when used systemically, can interact with other nephrotoxic drugs, potentially increasing the risk of renal impairment. While the systemic absorption of acyclovir from topical application is minimal, caution is advised in patients with pre-existing renal conditions or those taking other nephrotoxic agents.
Lidocaine, when absorbed systemically, can interact with antiarrhythmic drugs, such as amiodarone, beta-blockers, and other local anesthetics, potentially leading to additive cardiac effects. Although systemic absorption from topical application is typically low, patients with severe hepatic disease or those on medications affecting cardiac conduction should use this formulation with caution. Additionally, lidocaine may enhance the effects of other central nervous system depressants, such as benzodiazepines and opioids, which could lead to increased sedation or respiratory depression.
Patients should inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to assess the risk of potential interactions. Prescribers should evaluate the patient's overall medication regimen and health status to ensure the safe use of this topical gel. If any adverse reactions or unexpected symptoms occur, patients should contact their healthcare provider promptly.
For both patients and prescribers, it is crucial to understand that while the risk of systemic interactions is lower with topical formulations, vigilance is necessary, especially in patients with complex medical histories or those on multiple medications. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. We are here to assist you with any concerns or inquiries you may have regarding the safe and appropriate use of this medication.
The Acyclovir 50 mg/mL/Lidocaine HCl 20 mg/mL Topical Gel is a compounded formulation designed to deliver targeted treatment for viral skin infections, such as herpes simplex virus (HSV) outbreaks, while simultaneously providing localized pain relief. This semisolid gel is dispensed through a convenient pump mechanism, allowing for easy and precise application directly onto the affected skin areas. The gel-like consistency ensures that the active ingredients are absorbed efficiently, maximizing therapeutic effects while minimizing systemic exposure.
Acyclovir, an antiviral agent, works by inhibiting the replication of viral DNA. It specifically targets the viral DNA polymerase enzyme, which is essential for the virus to multiply and spread. By interfering with this process, acyclovir effectively reduces the viral load, shortens the duration of outbreaks, and helps in the healing of lesions. This action is particularly beneficial in managing conditions like herpes simplex, where rapid viral replication can lead to painful and recurrent outbreaks.
Lidocaine HCl, a local anesthetic, complements the antiviral action of acyclovir by providing immediate pain relief. It works by blocking sodium channels in the neuronal cell membrane, which inhibits the initiation and conduction of nerve impulses. This results in a numbing effect on the skin, alleviating the discomfort and pain associated with viral lesions. The combination of acyclovir and lidocaine in a single formulation offers a dual-action approach, addressing both the cause and the symptoms of the infection.
The topical gel formulation is particularly advantageous for patients who require localized treatment. The pump mechanism ensures that the correct dose is delivered with each application, reducing the risk of overuse or underuse. The gel's consistency allows it to adhere well to the skin, providing a protective barrier that enhances the absorption of the active ingredients while also preventing further irritation or infection of the affected area.
For prescribers, this compounded formulation offers a customizable treatment option that can be tailored to the specific needs of the patient. The concentration of active ingredients can be adjusted based on the severity of the condition and the patient's response to treatment. This flexibility is particularly useful in managing chronic or recurrent conditions where standard treatments may not be sufficient.
If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure the best possible outcomes for your patients.
This topical gel is used for the treatment of viral skin infections, such as cold sores, and provides pain relief due to its lidocaine content. The acyclovir helps to reduce the viral activity, while lidocaine offers local anesthetic effects to alleviate discomfort.
Apply a small amount of the gel to the affected area using the pump mechanism. Ensure the skin is clean and dry before application. Gently rub the gel into the skin until it is evenly distributed. Follow your healthcare provider's instructions regarding the frequency and duration of use.
No, you should not apply this gel to open wounds or broken skin. It is intended for use on intact skin only. If you have any concerns about your skin condition, consult your healthcare provider before use.
Some users may experience mild side effects such as skin irritation, redness, or a burning sensation at the application site. If you experience severe reactions or symptoms persist, discontinue use and consult your healthcare provider.
The pump mechanism is designed to dispense a precise amount of gel with each use, ensuring easy and accurate application. Simply press the pump to release the gel onto your fingertip or directly onto the affected area.
If you are pregnant or breastfeeding, consult your healthcare provider before using this gel. They will assess the potential risks and benefits to determine if it is appropriate for your situation.
Store the gel at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not freeze the gel, as this may affect its consistency and effectiveness.
The use of this gel in children should be determined by a healthcare provider. They will consider the child's age, weight, and medical condition before recommending its use.
Before using other topical medications in conjunction with this gel, consult your healthcare provider. They will advise you on potential interactions and the best course of action for your treatment plan.
If you miss a dose, apply it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra gel to make up for a missed dose.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
