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This formulation is a semisolid, gel-like compound of Amitriptyline HCl at 2% and Clonidine HCl at 0.232%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients in this topical gel are specifically designed for targeted treatment and absorption.
Amitriptyline HCl is a tricyclic antidepressant that is used to treat various forms of depression. Clonidine HCl is an alpha-2 adrenergic agonist that is commonly used to treat high blood pressure. When combined in this topical gel formulation, they work together to provide relief from certain disease states.
It's important to note that this formulation should be used as directed by a healthcare professional, and patients should always follow the prescribed dosage to ensure the best possible results.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation combines Amitriptyline HCl at a concentration of 2% and Clonidine HCl at a concentration of 0.232% in a topical gel. The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients are absorbed through the skin, providing targeted treatment.
Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. Clonidine HCl, on the other hand, is an alpha-2 adrenergic agonist. It is used in this formulation for its ability to manage neuropathic pain and certain types of inflammatory conditions. It works by blocking pain signals from reaching the brain.
This formulation is particularly useful in treating various disease states that involve chronic pain, such as fibromyalgia, neuropathic pain, and certain types of arthritis. It can also be used to manage pain associated with certain skin conditions. The topical application allows for targeted treatment, reducing systemic side effects often associated with oral administration of these medications.
Patients using this formulation should apply it as directed by their healthcare provider, typically to the affected area(s) once or twice daily. It's important to wash hands immediately after application unless the hands are the area being treated. Avoid contact with eyes, mouth, and other mucous membranes. Side effects may include skin irritation at the application site, drowsiness, dry mouth, and constipation. If these side effects persist or worsen, contact your healthcare provider immediately.
Prescribers should consider the patient's overall health status, other medications being taken, and the specific disease state being treated when deciding to use this formulation. Regular follow-ups should be scheduled to monitor the patient's response to treatment and adjust the dosage if necessary.
If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
Amitriptyline HCl and Clonidine HCl are both medications that can interact with a variety of other drugs. It's important to be aware of these potential interactions to ensure safe and appropriate use of this topical gel formulation.
Amitriptyline HCl, a tricyclic antidepressant, can interact with MAO inhibitors, leading to serious, potentially fatal, interactions. It's recommended to avoid MAO inhibitors for two weeks before, during, and two weeks after treatment with amitriptyline. Other significant interactions can occur with anticholinergic drugs, thyroid medications, antihypertensive drugs, and CNS depressants, including alcohol.
Clonidine HCl, an alpha-2 adrenergic agonist, can interact with beta-blockers, causing a rebound hypertension if either drug is discontinued abruptly. It can also interact with CNS depressants, leading to additive sedative effects. Other significant interactions can occur with antihypertensive drugs, cardiac glycosides, and tricyclic antidepressants.
Both amitriptyline and clonidine can cause additive CNS and respiratory depression if used with other CNS depressants, including alcohol, benzodiazepines, and opioids. Therefore, caution should be exercised when using these medications together.
It's also important to note that the absorption of these medications can be affected by the application site and the presence of skin lesions. Therefore, it's recommended to apply the gel to intact skin and avoid areas with cuts, abrasions, or irritations.
This formulation is used for the management of neuropathic pain, a type of chronic pain that can result from damage to or dysfunction of the nervous system. Amitriptyline works by increasing the levels of certain chemicals in the brain that help improve mood, sleep, and the body's response to pain. Clonidine works by decreasing the levels of certain chemicals in the blood to allow your blood vessels to relax and your heart to beat more slowly and easily.
It's crucial to inform your healthcare provider of all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements, to avoid potential drug interactions. If you have any questions or concerns about this formulation, please don't hesitate to reach out to us.
Amitriptyline HCl 2%/Clonidine HCl 0.232% Topical Gel is a unique formulation that combines two active ingredients, Amitriptyline HCl and Clonidine HCl, in a gel base for topical application. This formulation is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.
Amitriptyline HCl is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help improve mood, relieve anxiety, and treat certain types of chronic pain. When applied topically, Amitriptyline HCl can help to numb the skin and block pain signals, providing relief from conditions such as neuropathic pain, fibromyalgia, and post-herpetic neuralgia.
Clonidine HCl, on the other hand, is a medication that is primarily used to treat high blood pressure. It works by stimulating alpha-2 adrenergic receptors in the brain, which decreases cardiac output and lowers blood pressure. In a topical formulation, Clonidine HCl can help to reduce pain and inflammation by inhibiting the release of certain substances in the body that cause inflammation and pain.
The topical application allows for targeted treatment, reducing the risk of systemic side effects that can occur with oral administration of these medications. This makes the Amitriptyline HCl 2%/Clonidine HCl 0.232% Topical Gel an excellent option for patients who require long-term pain management.
It's important to note that while this formulation can provide significant relief from pain, it does not cure the underlying condition causing the pain. Therefore, it should be used as part of a comprehensive treatment plan under the supervision of a healthcare provider.
If you have any questions about the Amitriptyline HCl 2%/Clonidine HCl 0.232% Topical Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
It is a compounded formulation comprising two active ingredients: Amitriptyline HCl at 2% and Clonidine HCl at 0.232%. It is a semisolid formulation designed to be dispensed as a topical gel for targeted treatment.
The pump mechanism facilitates easy and precise application of the gel to the skin. This allows for consistent dosing and helps to minimize waste or spillage of the product.
It should be applied to the skin as directed by your healthcare professional. The pump dispenser ensures that the correct amount of the product is applied each time.
Yes, when used as directed by a healthcare professional. However, as with any medication, it's important to discuss your medical history and any current medications with your provider to avoid potential interactions or adverse reactions.
This product is designed for targeted treatment, meaning it is applied directly to the area requiring therapy. This can lead to a faster, more localized effect, reducing systemic side effects associated with oral intake of these drugs.
The gel has a semisolid, gel-like consistency. This ensures that it stays in place after application for effective absorption of the active ingredients.
After application, the gel is absorbed through the skin, allowing the active ingredients to perform their therapeutic functions. Always wash your hands after application to avoid unintentional transfer of medication to other parts of the body or to other people.
Before using other pharmacological products, especially other topical treatments, always consult your healthcare provider to avoid possible drug interactions.
No, it's essential to use only the amount prescribed by your healthcare provider. Exceeding the recommended dose does not speed up recovery and may increase the risk of side effects.
Individuals who have had allergic reactions to Amitriptyline HCl, Clonidine HCl, or any of the other ingredients in the gel should avoid using this product. Additionally, if you have certain health conditions or are pregnant, nursing or planning to conceive, consult with your healthcare provider before use.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
