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Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ascorbic Acid
L-Arginine

The Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel is a semisolid formulation designed for easy and precise application on the skin through a convenient pump mechanism. This gel-like consistency ensures targeted treatment and optimal absorption of active ingredients.

This formulation is used to treat various skin conditions, including promoting wound healing, reducing inflammation, and enhancing skin rejuvenation. It is particularly beneficial for patients with compromised skin integrity, aiding in the repair and maintenance of healthy skin.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ascorbic Acid
L-Arginine
Topical Gel
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Ascorbic Acid 12.5 mg/mL and L-arginine 100 mg/mL Topical Gel is a specialized formulation designed to deliver potent active ingredients directly to the skin. Dispensed through a convenient pump mechanism, this semisolid gel ensures precise application, allowing for targeted treatment and optimal absorption.

Ascorbic Acid, commonly known as Vitamin C, is a powerful antioxidant that plays a crucial role in collagen synthesis. By promoting collagen production, it helps in maintaining skin elasticity, reducing the appearance of fine lines and wrinkles, and enhancing overall skin texture. Additionally, its antioxidative properties protect the skin from free radical damage caused by environmental factors such as UV radiation and pollution.

L-arginine is an amino acid that serves as a precursor to nitric oxide, a molecule that supports vasodilation and enhances blood flow. When applied topically, L-arginine may improve microcirculation in the skin, facilitating better nutrient delivery and waste removal at the cellular level. This can contribute to healthier skin appearance and may support the natural healing processes.

The combination of Ascorbic Acid and L-arginine in a gel formulation offers synergistic benefits. While Ascorbic Acid works to rejuvenate and protect the skin, L-arginine enhances blood flow, potentially boosting the efficacy of the Vitamin C component. Together, they may aid in addressing various skin concerns such as uneven skin tone, dullness, and signs of aging.

For patients, this topical gel provides a non-invasive option to support skin health. The pump mechanism ensures that the product is dispensed hygienically and in consistent amounts, making it easy to incorporate into daily skincare routines. It is advisable to apply the gel to clean, dry skin once or twice daily or as directed by a healthcare professional. Patients should monitor their skin for any signs of irritation and consult their healthcare provider if any adverse reactions occur.

Prescribers may consider this formulation for patients seeking targeted skin therapies involving antioxidant support and enhanced microcirculation. The gel's composition allows for effective penetration of active ingredients, potentially improving clinical outcomes in skin maintenance and restorative treatments. It is important to assess each patient's medical history and concurrent medications to avoid any contraindications.

If you have any questions, reach out to us.

Drug Interactions

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Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel is a compounded formulation designed for targeted application on the skin, utilizing a pump mechanism for precise dosing. This formulation combines the antioxidant properties of ascorbic acid (vitamin C) with the vasodilatory effects of L-arginine, an amino acid that serves as a precursor to nitric oxide. The gel is intended for conditions where enhanced skin health and improved circulation are desired, potentially benefiting patients with localized skin issues or circulatory concerns.

When considering the use of this topical gel, it is important to be aware of potential drug interactions. Ascorbic acid, being a potent antioxidant, can interact with certain medications. For instance, it may affect the absorption and efficacy of oral anticoagulants like warfarin, potentially altering their anticoagulant effects. Patients on such medications should be monitored closely for changes in INR levels. Additionally, ascorbic acid can increase the absorption of iron, which may be of concern for patients with conditions like hemochromatosis or those taking iron supplements.

L-arginine, on the other hand, may interact with medications that affect blood pressure. As a precursor to nitric oxide, L-arginine can enhance vasodilation, potentially leading to additive hypotensive effects when used alongside antihypertensive drugs such as ACE inhibitors, beta-blockers, or diuretics. Patients using these medications should be monitored for signs of hypotension, such as dizziness or lightheadedness, especially when initiating or adjusting the dose of the topical gel.

Furthermore, L-arginine may interact with medications that influence nitric oxide pathways, such as phosphodiesterase inhibitors (e.g., sildenafil, tadalafil). The concurrent use of these agents may lead to enhanced vasodilatory effects, necessitating careful monitoring and possible dose adjustments to avoid adverse effects like severe hypotension.

Patients with a history of cardiovascular disease, particularly those with a history of myocardial infarction or angina, should use this formulation with caution. L-arginine has been associated with potential cardiovascular effects, and its use in such populations should be guided by a healthcare professional.

It is also important to consider potential allergic reactions or sensitivities to the components of the gel. Patients with known allergies to ascorbic acid or L-arginine should avoid using this formulation. Additionally, the gel base itself may contain excipients that could cause irritation or allergic reactions in sensitive individuals.

For both patients and prescribers, it is crucial to discuss the full medication profile, including over-the-counter drugs and supplements, to assess the risk of interactions. Regular follow-up and monitoring are recommended to ensure the safe and appropriate use of this topical gel. If you have any questions or concerns regarding the use of Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel, please reach out to us at Bayview Pharmacy for further guidance and support.

How Does it Work

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The Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel is a specialized formulation designed to deliver active ingredients directly to the skin, ensuring targeted treatment and optimal absorption. This semisolid gel is dispensed through a convenient pump mechanism, allowing for precise application and dosage control. The gel-like consistency ensures that the formulation spreads easily over the skin, enhancing the penetration of the active compounds into the targeted areas.

Ascorbic acid, commonly known as Vitamin C, is a potent antioxidant that plays a crucial role in skin health. It helps in neutralizing free radicals, which are unstable molecules that can cause oxidative stress and damage to skin cells. By reducing oxidative stress, ascorbic acid aids in preventing premature aging, reducing the appearance of fine lines and wrinkles, and promoting a more youthful complexion. Additionally, ascorbic acid is essential for collagen synthesis, a protein that provides structural support to the skin. Enhanced collagen production can lead to improved skin elasticity and firmness, contributing to overall skin rejuvenation.

L-arginine is an amino acid that serves as a precursor to nitric oxide, a molecule that plays a vital role in various physiological processes, including vasodilation. When applied topically, L-arginine can enhance blood flow to the skin, promoting better nutrient and oxygen delivery to the skin cells. This increased circulation can aid in the healing process of damaged skin, reduce inflammation, and improve overall skin tone and texture. Furthermore, L-arginine's role in protein synthesis supports the repair and regeneration of skin tissues, making it beneficial for conditions that require enhanced skin recovery.

The combination of ascorbic acid and L-arginine in this topical gel formulation provides a synergistic effect, targeting multiple pathways to improve skin health. This formulation is particularly beneficial for individuals seeking to address skin conditions associated with oxidative stress, impaired collagen production, and poor circulation. By delivering these active ingredients directly to the skin, the gel ensures that the therapeutic effects are localized, minimizing systemic exposure and potential side effects.

For patients and prescribers considering this formulation, it is important to understand the specific skin conditions and treatment goals to determine the appropriateness of this therapy. The precise application facilitated by the pump mechanism allows for tailored dosing, which can be adjusted based on the severity of the condition and the patient's response to treatment. As with any topical formulation, it is recommended to perform a patch test to assess skin sensitivity and tolerance before widespread application.

If you have any questions or require further information about the Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation or its use in specific disease states.

Frequently Asked Questions

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What is the purpose of Ascorbic Acid in this topical gel?

Ascorbic Acid, also known as Vitamin C, is included in the formulation for its antioxidant properties. It helps protect the skin from free radical damage, promotes collagen production, and can improve skin texture and tone.

How does L-arginine benefit the skin in this formulation?

L-arginine is an amino acid that supports skin health by promoting wound healing and improving blood flow. It can enhance the delivery of nutrients to the skin, aiding in repair and rejuvenation.

How should I apply this topical gel?

Dispense the gel through the pump mechanism and apply a thin layer to the targeted area of the skin. Gently massage until fully absorbed. Follow the specific instructions provided by your healthcare provider or pharmacist.

Can this gel be used on all skin types?

Yes, this gel is generally suitable for all skin types. However, if you have sensitive skin or specific skin conditions, it is advisable to perform a patch test or consult with a healthcare professional before use.

How often should I use this topical gel?

The frequency of application should be determined by your healthcare provider. Typically, it may be used once or twice daily, but follow the specific guidance provided for your treatment plan.

Are there any side effects associated with this gel?

Some users may experience mild irritation, redness, or a tingling sensation upon application. If you experience severe or persistent side effects, discontinue use and consult a healthcare professional.

Can I use this gel with other skincare products?

Yes, this gel can generally be used alongside other skincare products. However, it is recommended to apply it on clean skin and allow it to absorb fully before applying other products. Consult with a healthcare professional if you have concerns about specific product interactions.

Is this gel safe to use during pregnancy?

While the ingredients in this gel are generally considered safe, it is important to consult with a healthcare provider before using any new skincare products during pregnancy.

How should I store this topical gel?

Store the gel in a cool, dry place away from direct sunlight and heat. Ensure the cap is tightly closed after each use to maintain the product's efficacy and prevent contamination.

What should I do if I miss a dose of this gel?

If you miss an application, apply the gel as soon as you remember. If it is almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply extra gel to make up for a missed dose.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ascorbic Acid 12.5 mg/mL/L-arginine 100 mg/mL Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily