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Formulas

Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 5% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Bupivacaine Hydrochloride
Diclofenac Sodium
Baclofen

This formulation is a semisolid, gel-like compound containing Baclofen 2%, Bupivacaine HCl 1%, and Diclofenac Sodium 5%. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The active ingredients in this formulation are designed to target and treat specific disease states.

Baclofen is a muscle relaxant and antispastic agent, used to alleviate symptoms associated with muscle spasms, stiffness, and pain. Bupivacaine HCl is a local anesthetic, providing temporary numbness or loss of sensation in the area where applied. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation.

Together, these ingredients work synergistically to provide relief from conditions such as muscle pain, inflammation, and localized discomfort.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Bupivacaine Hydrochloride
Diclofenac Sodium
Baclofen
Topical Gel
6536ecc80b645e7c67a1bd33
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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This formulation combines Baclofen, Bupivacaine HCl, and Diclofenac Sodium in a topical gel format. Baclofen is a muscle relaxant and antispastic agent, Bupivacaine HCl is a local anesthetic, and Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). Together, these three active ingredients work synergistically to provide pain relief, reduce inflammation, and relax muscles.

The gel is dispensed through a pump mechanism, which allows for easy and precise application. This is particularly beneficial for patients who need targeted treatment, as the gel can be applied directly to the affected area. The semisolid formulation ensures that the active ingredients are absorbed through the skin, providing localized relief without the systemic side effects that can occur with oral medications.

This formulation is used to treat a variety of disease states. Baclofen can help with conditions such as multiple sclerosis and spinal cord injury, where muscle spasms can cause significant discomfort. Bupivacaine HCl is often used in post-surgical pain management, and can also be beneficial for patients with chronic pain conditions. By combining these three medications in one topical gel, patients can receive comprehensive pain management in a convenient and easy-to-use format.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Side effects can include skin irritation at the application site, and more serious side effects can occur if the medication is used more frequently or at a higher dose than recommended. If you have any questions about this formulation, or if you experience any side effects, please reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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This formulation contains three active ingredients: Baclofen, Bupivacaine HCl, and Diclofenac Sodium. Each of these drugs has its own potential interactions, which can be exacerbated when used in combination. It's important to note that this formulation is intended for topical use only, which can reduce the risk of systemic interactions but does not eliminate it entirely.

Baclofen is a muscle relaxant and antispasmodic agent. It may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. Concurrent use with antihypertensive drugs may lead to additive hypotensive effects.

Bupivacaine HCl is a local anesthetic. It can interact with other local anesthetics and Class I antiarrhythmic drugs, potentially leading to additive systemic toxicity. It may also interact with drugs that can cause methemoglobinemia, such as sulfonamides, nitrites, and certain antimalarial drugs.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). It may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of bleeding. Concurrent use with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers may reduce their antihypertensive effects. Diclofenac may also interact with lithium and methotrexate, potentially increasing their toxicity.

This formulation is used to treat various disease states, primarily those involving pain and inflammation. Baclofen can help to relieve muscle spasms and spasticity, Bupivacaine HCl can provide local anesthesia, and Diclofenac Sodium can reduce inflammation and pain. However, the combined use of these drugs in a single formulation requires careful monitoring to avoid potential interactions and adverse effects.

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter drugs, and herbal supplements. They should also avoid alcohol and be cautious when driving or operating machinery until they know how this formulation affects them.

Prescribers should consider the potential interactions of this formulation with other drugs the patient is taking. They should monitor the patient for signs of adverse effects and adjust the treatment plan as necessary. They should also educate the patient about the potential risks and benefits of this formulation, and advise them to seek medical attention if they experience any unusual symptoms.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to help ensure the safe and appropriate use of this medication.

How Does it Work

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This formulation combines three active ingredients: Baclofen, Bupivacaine HCl, and Diclofenac Sodium. Each of these ingredients plays a unique role in managing pain and inflammation.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. This makes it particularly useful in conditions where muscle spasms are a key symptom, such as multiple sclerosis or spinal cord injuries.

Bupivacaine HCl is a local anesthetic. It works by blocking nerve impulses in the body, which helps to numb the area and reduce pain. This can be particularly beneficial for localized pain relief, such as post-surgical pain or pain associated with nerve damage.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause pain and inflammation.

The gel formulation allows for targeted application of these active ingredients. By applying the gel directly to the affected area, patients can experience relief where they need it most. The semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application. This can help to ensure that the correct dose is applied each time, and can also reduce the risk of side effects associated with systemic absorption of these medications.

It's important to note that while this formulation can provide significant relief for many patients, it's not suitable for everyone. Patients with certain medical conditions or who are taking certain other medications may not be able to use this formulation. Always consult with a healthcare provider before starting any new medication.

If you have any questions about this formulation, or if you'd like to know more about how it could benefit you or your patients, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is the content of this compounded formulation?

The compounded formulation contains Baclofen 2%, Bupivacaine HCl 1%, and Diclofenac Sodium 5%. All of these active ingredients are present in a gel-like consistency and they are dispensed through a pump mechanism.

How should I apply this compounded formulation?

This compounded formulation is designed to be applied topically on the skin. Using the pump mechanism, you can easily dispense the required amount of product for application.

Will this medication be absorbed into my skin?

Yes, the active ingredients of this medication are absorbed by your skin for targeted treatment.

Can I use this medication for any area of my skin?

Your healthcare provider will advise you on specific areas of your skin where this medication is to be used. Always follow the instructions provided by your healthcare provider.

What does a semisolid formulation mean?

A semisolid formulation refers to the physical state of the medication. It is not completely solid, rather it maintains a gel-like consistency that can be easily spread onto the skin.

What is the function of the pump mechanism in this medication?

The pump mechanism in this medication's container allows easy and precise dispensing of the medication. It helps to dispense the right amount of product for each use.

How is this medication stored?

Generally, this compounded formulation should be stored in a cool, dry place, away from heat and direct sunlight. The exact storage instructions can be found on the medication package or advised by your healthcare provider.

Can this medication be used for children?

Whether this formulation is suitable for use in children depends on their health and age. It is best to consult with a healthcare provider for advice tailored to the individual’s health history and needs.

Can I use this medication if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult with your healthcare provider before using this medication to consider potential risks and benefits.

Are there any side effects associated with this medication?

All medications can have potential side effects, which may include skin irritation or sensitivity at the site of application. If you notice any discomfort or adverse effects, stop using the formulation and consult with your healthcare provider immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily