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Formulas

Ciclopirox Olamine 8%/Ibuprofen 2%/Terbinafine HCl 1%/Urea 20% Topical Nail Lacquer

FDA-approved generic
Dose form
Nail Solution
Active ingredients
Ciclopirox Olamine
Ibuprofen
Terbinafine Hydrochloride
Urea

This Ciclopirox Olamine 8%/Ibuprofen 2%/Terbinafine HCl 1%/Urea 20% Topical Nail Lacquer is a specially formulated liquid designed for direct application to the nails. It is primarily used to treat various nail conditions such as fungal infections, brittleness, and discoloration. The active ingredients in this formulation work synergistically to combat fungal infections, reduce inflammation, and promote healthy nail growth.

Ciclopirox Olamine and Terbinafine HCl are antifungal agents that work to eradicate nail fungus, a common cause of nail discoloration and brittleness. Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), helps to reduce inflammation and pain associated with these conditions. Urea, a keratolytic, aids in softening and breaking down the damaged nail, promoting the penetration of the antifungal agents and enhancing their efficacy.

By delivering these therapeutic agents directly to the nails, this topical nail lacquer not only treats the underlying conditions but also improves the overall appearance of the nails, promoting healthier and stronger nail growth.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ciclopirox Olamine
Ibuprofen
Terbinafine Hydrochloride
Urea
Nail Solution
65394f5088e3acdffd34b421
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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This formulation is a unique combination of Ciclopirox Olamine 8%, Ibuprofen 2%, Terbinafine HCl 1%, and Urea 20% in a topical nail lacquer. It is specifically designed to treat a variety of nail conditions, including fungal infections, brittleness, and discoloration. The formulation is applied directly to the nails, allowing for targeted treatment and improved nail health.

Ciclopirox Olamine is an antifungal agent that works by inhibiting the growth of fungus on the nails. By applying Ciclopirox Olamine directly to the nail, it can penetrate the nail plate and eradicate the fungal infection at its source.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation, pain, and swelling. In this formulation, it can help to alleviate any discomfort or inflammation associated with nail conditions, making it easier for patients to continue with their daily activities.

Terbinafine HCl is another antifungal medication that works by stopping the growth of fungus. By combining Terbinafine HCl with Ciclopirox Olamine, this formulation provides a broad-spectrum antifungal treatment that can effectively treat a wide range of nail fungal infections.

Urea is a keratolytic agent that works by softening and breaking down the thickened skin on the nail, allowing the other medications in the formulation to penetrate more effectively. It also helps to improve the overall appearance of the nail by reducing brittleness and discoloration.

This formulation is applied directly to the nails, allowing for targeted treatment and improved nail health. It is important to use this medication as directed by your healthcare provider, and to continue using it for the full course of treatment, even if symptoms improve after a few days. This will ensure that the infection is completely treated and help to prevent it from returning.

If you have any questions about this formulation, or if you would like more information about how it can be used to treat your specific nail condition, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Drug Interactions

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The combination of Ciclopirox Olamine, Ibuprofen, Terbinafine HCl, and Urea in this topical nail lacquer formulation is designed to treat a variety of nail conditions. However, it's important to be aware of potential drug interactions that may occur with this formulation.

Ciclopirox Olamine is an antifungal agent that works by inhibiting the growth of fungus on the nails. It is generally well-tolerated with minimal systemic absorption, thus the likelihood of drug interactions is low. However, it's important to avoid using other topical products on the same area without consulting a healthcare provider, as this may alter the absorption and effectiveness of Ciclopirox Olamine.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. While systemic absorption from topical application is minimal, it's still important to consider potential interactions. Patients taking anticoagulants, antiplatelet drugs, or other NSAIDs should use this formulation with caution, as concurrent use may increase the risk of bleeding. Additionally, Ibuprofen may decrease the effectiveness of certain blood pressure medications.

Terbinafine HCl is another antifungal agent that works by stopping the growth of fungus. It's important to note that oral Terbinafine can interact with a wide range of medications, including certain antidepressants, beta-blockers, and antifungal drugs. However, the risk of interactions is significantly lower with topical application. Still, patients should avoid using other topical products on the same area without consulting a healthcare provider.

Urea is a keratolytic agent that helps to soften and remove thick, hard, or dry skin. It is unlikely to interact with other medications. However, it may increase the absorption of other topical medications used on the same area, potentially enhancing their effects and side effects.

Overall, while the risk of drug interactions with this topical nail lacquer formulation is low, it's important for patients to inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter products, and dietary supplements. This will help to ensure safe and appropriate use of this formulation.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

How Does it Work

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The Ciclopirox Olamine 8%/Ibuprofen 2%/Terbinafine HCl 1%/Urea 20% Topical Nail Lacquer is a specially formulated medication designed to treat a variety of nail conditions. This formulation combines four active ingredients, each with a unique mechanism of action, to provide comprehensive treatment.

Ciclopirox Olamine, an antifungal agent, works by inhibiting the growth of fungus on the nails. It interferes with the synthesis of DNA and RNA, which are essential for fungal cell growth and reproduction. This disruption prevents the fungus from spreading, allowing the nail to heal and return to its normal state.

Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), provides pain relief and reduces inflammation. It works by blocking the production of prostaglandins, substances in the body that cause inflammation and pain. This helps to alleviate discomfort and swelling associated with nail infections.

Terbinafine HCl is another antifungal medication that works by stopping the growth of fungus. It specifically inhibits a fungal enzyme called squalene epoxidase, disrupting the production of ergosterol, a vital component of the fungal cell membrane. This causes the cell membrane to weaken and leads to the death of the fungal cells, thereby treating the infection.

Urea, a keratolytic, helps to soften and break down the thickened, damaged, or diseased parts of the nail. It works by increasing the amount of water in the skin, which helps to loosen and shed hard, scaly, or crusty skin. This allows the other active ingredients in the formulation to penetrate more effectively into the nail, enhancing their therapeutic effects.

Together, these four ingredients work synergistically to treat nail conditions such as fungal infections, brittleness, or discoloration. They provide targeted treatment, delivering medication directly to the nails to promote healthy nail growth and improve overall nail appearance.

If you have any questions about this formulation or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is this compounded formulation made of?

This compounded formulation consists of Ciclopirox Olamine 8%, Ibuprofen 2%, Terbinafine HCl 1%, and Urea 20%.

How is this formulation meant to be used?

This is a liquid formulation that is specifically designed for topical application to the nails.

What conditions does this formulation treat?

We formulated this product to treat nail conditions such as fungal infections, brittleness, or discoloration. It is designed to deliver medication directly to the nails to promote healthy nail growth and improve overall nail appearance.

How does this formulation work?

This formulation works by delivering therapeutic agents directly to the nails to treat various nail conditions, improve the overall nail growth, and appearance.

What are the benefits of this formulation over others on the market?

This formulation provides targeted treatment to the nails, combining multiple active ingredients to manage various symptoms in a single application. It is capable of treating a wide spectrum of nail conditions effectively.

How frequently should I use this nail lacquer formulation?

The recommended frequency of use will depend on the severity of your condition. Please consult your healthcare provider for an accurate treatment plan.

Can I use other topical products while using this formulation?

You should discuss this with your healthcare provider before doing so to avoid any potential interactions that could decrease the effectiveness of any of the products you are using.

What are the potential side effects of this formulation?

While side effects vary from person to person, if you experience any discomfort or allergic reactions after using the product, you should immediately stop using it and contact your healthcare provider.

Can pregnant or breastfeeding women use this formulation?

Pregnant or breastfeeding women should consult their healthcare professional before starting any new medication, including this nail lacquer formulation.

How should I store this nail lacquer formulation?

Store the product in a cool, dry place away from direct sunlight. Keep it away from children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ciclopirox Olamine 8%/Ibuprofen 2%/Terbinafine HCl 1%/Urea 20% Topical Nail Lacquer
Nail Solution
15 mL
controlled

Apply topically to affected area(s)

Once daily