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Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet)

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Clomipramine Hydrochloride

Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet) is a semisolid formulation dispensed through a pump mechanism. This formulation is designed for easy and precise application on the skin, allowing for targeted treatment or absorption of the active ingredient, Clomipramine HCl, in a gel-like consistency. This veterinary medication is primarily used to treat various disease states in animals, including obsessive-compulsive disorders, separation anxiety, and certain types of aggression.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clomipramine Hydrochloride
Topical Gel
653ea7979167ec8bc024df38
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet) is a specialized formulation designed for easy and precise application on the skin. This semisolid formulation is dispensed through a pump mechanism, which allows for targeted treatment or absorption of the active ingredients. The gel-like consistency ensures that the medication is absorbed slowly and steadily, providing a sustained release of the active ingredient, Clomipramine HCl.

Clomipramine HCl is a tricyclic antidepressant (TCA) that is primarily used in veterinary medicine to manage various behavioral disorders in pets. It works by increasing the levels of certain chemicals in the brain that help reduce feelings of anxiety and obsessive-compulsive behaviors.

Transdermal delivery of Clomipramine HCl offers several advantages over oral administration. It bypasses the gastrointestinal tract, reducing the risk of gastrointestinal side effects. It also allows for a more steady absorption of the drug, which can lead to more consistent therapeutic effects. Furthermore, transdermal application can be a more convenient and less stressful method of administration for pets and their owners.

Some pets may experience side effects such as drowsiness, dry mouth, or urinary retention. It's also contraindicated in pets with certain medical conditions, such as glaucoma or certain heart conditions. Therefore, it's crucial that this medication is used under the guidance of a qualified veterinary professional.

As compounding pharmacists, we are committed to providing high-quality, personalized medications to meet the unique needs of each patient. We are always available to answer any questions or concerns you may have about this formulation. Please don't hesitate to reach out to us if you need any further information.

Drug Interactions

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Clomipramine HCl is a tricyclic antidepressant (TCA) that is primarily used in veterinary medicine to treat behavioral disorders in pets, such as separation anxiety, obsessive-compulsive disorder, and certain types of aggression. It works by increasing the levels of certain chemicals in the brain that help reduce the symptoms of these disorders. However, like all medications, Clomipramine HCl can interact with other drugs, which can affect how it works or increase the risk of side effects.

One of the most significant drug interactions to be aware of is with monoamine oxidase inhibitors (MAOIs), such as selegiline. Combining these two types of medications can lead to a potentially life-threatening condition called serotonin syndrome, characterized by symptoms such as agitation, hallucinations, rapid heartbeat, fever, and loss of coordination. Therefore, it is crucial to avoid using Clomipramine HCl in pets that are currently taking or have recently taken an MAOI.

Clomipramine HCl can also interact with certain anticholinergic drugs, such as atropine or benztropine. These medications can increase the risk of side effects from Clomipramine HCl, including dry mouth, constipation, and difficulty urinating. Additionally, using Clomipramine HCl with other central nervous system depressants, such as sedatives, anesthetics, or opioid pain medications, can increase the risk of severe drowsiness, respiratory depression, and even coma.

Furthermore, Clomipramine HCl can interact with certain heart medications, such as beta-blockers or calcium channel blockers. This interaction can affect the heart's rhythm and function, potentially leading to serious cardiovascular effects. Therefore, it is essential to monitor pets closely if they are taking these medications together.

Lastly, Clomipramine HCl can interact with thyroid medications, potentially reducing their effectiveness. Therefore, if your pet is taking a thyroid medication, their thyroid levels may need to be monitored more closely while they are using Clomipramine HCl.

It's important to note that this is not a complete list of all possible drug interactions. Therefore, it is crucial to inform your veterinarian of all the medications your pet is currently taking, including prescription drugs, over-the-counter medications, and dietary supplements. If you have any questions or concerns about potential drug interactions, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to help ensure the safe and appropriate use of Clomipramine HCl for your pet.

How Does it Work

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Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet) is a specially formulated medication designed for transdermal (through the skin) administration. The active ingredient, Clomipramine HCl, is a tricyclic antidepressant (TCA) that works by affecting the balance of certain natural chemicals (neurotransmitters) in the body. Specifically, it inhibits the reuptake of serotonin and norepinephrine, thereby increasing their levels in the brain and helping to restore normal mood and behavior.

The gel formulation is designed to be easily applied to the skin, where it is absorbed into the bloodstream. This method of administration bypasses the digestive system, reducing the risk of gastrointestinal side effects and improving the bioavailability of the drug. The pump mechanism allows for precise dosing, ensuring that the patient receives the correct amount of medication each time.

Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet) is primarily used in veterinary medicine to treat behavioral disorders in pets, such as separation anxiety and obsessive-compulsive disorder (OCD). It can also be used to treat certain types of pain and to control the symptoms of depression. The medication works by helping to restore the balance of certain natural substances (serotonin, among others) in the brain.

It's important to note that while Clomipramine HCl can help manage symptoms, it is not a cure for these conditions. Long-term use may be necessary, and it may take several weeks to see an improvement in symptoms. As with any medication, it's important to follow the prescribing veterinarian's instructions closely and to monitor the patient for any potential side effects.

If you have any questions about Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet), or if you need further information about its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is always here to help.

Frequently Asked Questions

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What is Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet)?

Clomipramine HCl is a medication in a gel-like consistency form designed for transdermal application in animals. It is dispensed through a pump mechanism for easy and precise application.

How does this specific dose form of Clomipramine HCl work?

This is a semisolid formulation that when applied to the skin allows for targeted treatment or absorption of the active ingredients into the bloodstream through the skin layer.

How do I administer Clomipramine HCl Transdermal Gel to my pet?

It is administered via a pump mechanism directly on the skin. Always follow the vet's instructions and the guidelines provided on the product.

Can this formulation be ingested orally?

No, Clomipramine HCl Transdermal Gel is not for oral ingestion. It is designed specifically for transdermal or skin application.

What are some of the advantages of transdermal gel?

Transdermal gels have several advantages such as easy application, precise dosing, increased compliance, quick onset of action and reduced side effects as it does not go through the digestive system.

What should I do if my pet experiences side effects from this medication?

If your pet experiences any side effects, it is important to contact your vet immediately. Side effects could include skin irritation from the gel application.

What precautions should I take while using Clomipramine HCl Transdermal Gel?

Always ensure the medication is applied on clean, unbroken and dry skin. Avoid getting the formulation into the eyes or mouth of the animal. Always wash your hands thoroughly after handling the medication.

Can I use Clomipramine HCl Transdermal Gel in puppies or kittens?

Whether this medication is suitable for puppies or kittens should be determined by your vet. It is important to follow your vet's instructions about dosage and frequency of medication.

Do I need to refrigerate Clomipramine HCl Transdermal Gel?

No. However, always store it as instructed by your vet or as indicated on the product instructions, ensuring it is kept out of reach from children and animals when not in use.

What if I miss a dose?

If a dose is missed, apply it as soon as remembered. However, if it is close to the next dose, skip the missed dose and revert back to the regular schedule. Do not double the doses unless instructed by your vet.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clomipramine HCl 2 mg/0.1 mL Transdermal Gel (Vet)
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily