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Clotrimazole 2%/Hydrocortisone 2% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Clotrimazole
Hydrocortisone

Clotrimazole 2%/Hydrocortisone 2% Topical Cream is a specially compounded semisolid preparation, dispensed via a pump mechanism for easy and controlled application. This formulation is designed to deliver localized treatment on the skin, ensuring optimal absorption of the active ingredients.

The cream contains two active ingredients: Clotrimazole, an antifungal agent, and Hydrocortisone, a corticosteroid. Clotrimazole works by inhibiting the growth of fungus, while Hydrocortisone reduces inflammation, itching, and redness.

This formulation is primarily used to treat a variety of skin conditions, including fungal infections, eczema, dermatitis, allergies, and rash. The combined action of Clotrimazole and Hydrocortisone effectively manages the symptoms of these disease states, providing relief and promoting healing.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clotrimazole
Hydrocortisone
Topical Cream
653f62464cf12af34ba423e0

Formula Information

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Clotrimazole 2%/Hydrocortisone 2% Topical Cream is a specially compounded medication that combines the antifungal properties of clotrimazole with the anti-inflammatory and immunosuppressive effects of hydrocortisone. This dual-action cream is designed to treat a variety of skin conditions, providing both relief from symptoms and targeting the underlying cause of the condition.

Clotrimazole is an antifungal medication that works by inhibiting the growth of fungus. It is commonly used to treat skin infections such as athlete's foot, jock itch, and ringworm, as well as vaginal yeast infections. By incorporating clotrimazole into this topical cream, we can directly target the site of the infection, reducing the spread of the fungus and relieving symptoms such as itching, burning, and cracking of the skin.

Hydrocortisone, on the other hand, is a corticosteroid that works by reducing inflammation and suppressing the immune response. When combined with clotrimazole in this topical cream, hydrocortisone can help to reduce the redness, swelling, and itching associated with these conditions, providing relief from symptoms while the antifungal medication works to eliminate the infection.

The cream is dispensed in a pump mechanism, which allows for convenient and controlled application. This ensures that the correct amount of medication is applied each time, reducing the risk of overuse or underuse. The semisolid preparation is designed to be easily absorbed by the skin, allowing for localized treatment of the affected area.

As with any medication, it is important to use Clotrimazole 2%/Hydrocortisone 2% Topical Cream as directed by your healthcare provider. Side effects may include burning, stinging, swelling, or irritation at the application site. If these side effects persist or worsen, or if you experience any other side effects, contact your healthcare provider immediately.

At Bayview Pharmacy, we are committed to providing high-quality, personalized care to all of our patients. If you have any questions about Clotrimazole 2%/Hydrocortisone 2% Topical Cream, or if you would like more information about our compounding services, please do not hesitate to reach out to us. We are here to help.

Drug Interactions

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Clotrimazole 2%/Hydrocortisone 2% Topical Cream is a combination medication that is used to treat a variety of skin conditions such as eczema, dermatitis, allergies, and rash. Clotrimazole is an antifungal medication that works by stopping the growth of certain types of fungus, while Hydrocortisone is a mild corticosteroid that reduces the swelling, itching, and redness that can occur in these types of conditions.

It is important to be aware of potential drug interactions when using this medication. While Clotrimazole 2%/Hydrocortisone 2% Topical Cream is applied topically and is therefore less likely to interact with other medications taken orally or injected, there are still some potential interactions to be aware of. For example, using this medication at the same time as other topical medications that contain corticosteroids could increase the risk of side effects.

Additionally, certain medications can affect the way that hydrocortisone is metabolized in the body, potentially leading to increased levels of the drug in the blood. These medications include certain types of antifungal medications, such as ketoconazole and itraconazole, as well as certain types of antibiotics, such as erythromycin and clarithromycin. If you are taking any of these medications, it is important to let your healthcare provider know before starting treatment with Clotrimazole 2%/Hydrocortisone 2% Topical Cream.

It is also important to note that while Clotrimazole 2%/Hydrocortisone 2% Topical Cream is generally safe to use during pregnancy, it should be used only if clearly needed and under the supervision of a healthcare provider. The same applies to breastfeeding mothers, as it is not known whether this medication passes into breast milk.

As always, it is important to use this medication only as directed by your healthcare provider, and to inform them of all other medications and supplements that you are currently taking. This includes prescription and over-the-counter medications, as well as any vitamins, herbal supplements, or other natural health products. If you have any questions about potential drug interactions or other aspects of this medication, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to help.

How Does it Work

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Clotrimazole 2%/Hydrocortisone 2% Topical Cream is a combination medication that works by targeting two key aspects of skin conditions: infection and inflammation.

Clotrimazole, the first active ingredient, is an antifungal medication. It works by inhibiting the growth of fungus by interfering with the production of the fungal cell membrane. The cell membrane is crucial for the survival and growth of the fungus. When clotrimazole disrupts its production, the cell membrane becomes unstable and begins to leak, eventually leading to the death of the fungal cells, thereby treating the infection.

The second active ingredient, hydrocortisone, is a corticosteroid that works by reducing inflammation. It does this by suppressing the immune system's response to injury or irritation. When applied to the skin, hydrocortisone reduces the swelling, itching, and redness that can occur with various skin conditions. This provides relief from symptoms and promotes healing.

The cream is dispensed in a pump mechanism, which allows for convenient and controlled application. This ensures that the right amount of medication is applied to the affected area, maximizing its effectiveness while minimizing potential side effects. The cream is designed to be absorbed through the skin, directly targeting the area of concern.

It can also be used to treat eczema, psoriasis, and other inflammatory skin conditions. The combination of clotrimazole and hydrocortisone provides both immediate relief from symptoms and a long-term solution to the underlying infection or inflammation.

As with any medication, it's important to use this cream as directed by a healthcare provider. Overuse or misuse can lead to side effects and may decrease the effectiveness of the medication. If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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In addition to the common indications for Clotrimazole 2%/Hydrocortisone 2% Topical Cream, there are several other potential uses based on the mechanism of action of the active ingredients. Firstly, the potent antifungal agent clotrimazole, makes this formulation useful in the treatment of various fungal skin infections not limited to tinea pedis, tinea cruris, tinea corporis, and tinea versicolor. Secondly, hydrocortisone, a topical corticosteroid, aids in reducing inflammation and swelling. This property could make it beneficial in managing other dermatological conditions associated with inflammation such as psoriasis, moderate forms of eczema, and lichen planus. Please note that while these uses are scientifically plausible, their effectiveness can vary depending on individuals' specific skin conditions and responses to therapy.

For prescribers considering this formulation for off-label uses besides the ones mentioned above, it's essential to bear in mind the potential side effects of the active ingredients. Long-term use of topical corticosteroids like hydrocortisone may lead to skin atrophy, striae, telangiectasia, and may suppress the hypothalamic-pituitary-adrenal axis if used in large quantities or under occlusion. Clotrimazole, on the other hand, is generally well-tolerated, with skin irritation being the most common side effect.

Patient education is paramount when considering this formulation for off-label uses. Patients should be aware of the potential side effects and be counseled on proper application techniques to minimize the risk of adverse events. Direct patients to apply a thin layer of the cream to the affected area(s) and gently rub in until fully absorbed. Usage should be limited to two weeks. If no improvement is observed after 1-2 weeks or the condition worsens, discontinue use and advise the patient to contact their healthcare provider.

Patient monitoring is necessary. Regular follow-up appointments or telemedicine check-ins can be beneficial, including assessment for improvement in symptoms, signs of adverse effects, and patient's overall satisfaction with treatment.

Should you have any questions or require more information on the other uses of Clotrimazole 2%/Hydrocortisone 2% Topical Cream, please feel free to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always ready to assist you.

Frequently Asked Questions

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What is Clotrimazole 2%/Hydrocortisone 2% Topical Cream?

This is a semisolid preparation that contains two active ingredients, Clotrimazole and Hydrocortisone. Clotrimazole is an antifungal that works by preventing the growth of fungus, while Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness that can occur in various skin problems.

How is the Clotrimazole 2%/Hydrocortisone 2% Topical Cream dispensed?

This cream is dispensed in a pump mechanism, which is designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of active ingredients.

How do I use Clotrimazole 2%/Hydrocortisone 2% Topical Cream?

The cream should be applied to the affected skin area as directed by a healthcare provider. It is intended for external use only, and direct contact with the eyes, mouth, or other mucous membranes should be avoided.

Can I use Clotrimazole 2%/Hydrocortisone 2% Topical Cream Internally?

No, this cream is specifically designed for topical, or external, use only. Do not ingest it or apply it internally.

What conditions is this Clotrimazole 2%/Hydrocortisone 2% Topical Cream used to treat?

Clotrimazole 2%/Hydrocortisone 2% cream is commonly used to treat a variety of skin conditions such as inflammatory skin disorders, fungal skin infections, and others that cause symptoms like redness, itching, and swelling.

Can I use this cream if I have known allergies?

If you have known allergies to either Clotrimazole, Hydrocortisone, or any other ingredient in the cream, you should not use it. Always inform your healthcare provider of any known allergies before starting a new medication.

Can I use the cream with other skin products?

Before applying other skin products with Clotrimazole 2%/Hydrocortisone 2% cream, consult your healthcare provider. In some cases, certain products may interfere with the effectiveness of the cream or increase the risk of skin reactions.

What should I do if I miss a dose?

If you miss a dose, apply the cream as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule.

What are the side effects of Clotrimazole 2%/Hydrocortisone 2% Topical Cream?

Common side effects may include redness, burning, stinging, swelling, or irritation at the application site. If these persist or worsen, or if you experience more serious side effects such as stretch marks, hair growth, or skin color changes, contact your healthcare provider promptly.

What should I do in case of an overdose?

If you suspect an overdose, if the cream has been ingested, or if there is a significant adverse reaction, seek professional help or contact a Poison Control Center immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clotrimazole 2%/Hydrocortisone 2% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)