The Cyclobenzaprine HCl 1%/Ibuprofen 20% Transdermal Gel is a semisolid formulation dispensed through a pump mechanism. This formulation is designed to facilitate easy and precise application on the skin, allowing for targeted treatment or absorption of the active ingredients. The gel-like consistency ensures a smooth application process.
This formulation combines the muscle relaxant properties of Cyclobenzaprine HCl and the anti-inflammatory and pain-relieving effects of Ibuprofen. It is primarily used to treat conditions such as muscle spasms, inflammation, and pain associated with various disease states. The transdermal delivery allows for direct application to the affected area, providing localized relief while minimizing systemic side effects.

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This formulation combines two active ingredients, Cyclobenzaprine HCl at 1% and Ibuprofen at 20%, in a transdermal gel. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is commonly used to treat skeletal muscle conditions such as pain or injury. On the other hand, Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It is used to reduce pain, inflammation, and stiffness caused by many conditions, including arthritis, bursitis, and gout attacks.
The transdermal gel formulation allows for targeted treatment, as it can be applied directly to the area of discomfort. This is particularly beneficial for patients who may have difficulty swallowing tablets or those who prefer not to take medication orally. The gel is dispensed through a pump mechanism, which allows for easy and precise application. The semisolid consistency of the gel ensures that it stays on the skin, allowing for optimal absorption of the active ingredients.
It's important to note that while this formulation can provide significant relief for muscle pain and inflammation, it should be used as part of a comprehensive treatment plan that may include rest, physical therapy, or other pain relief measures. As with any medication, it's crucial to use this formulation as directed by a healthcare provider to ensure its safety and effectiveness. Side effects can occur, including skin irritation at the application site, so it's important to monitor for any adverse reactions.
For prescribers, this formulation offers a versatile treatment option that can be tailored to the individual needs of each patient. It can be particularly useful for patients who have localized pain or inflammation, or those who have difficulty with oral medications. As always, it's important to consider the overall health status of the patient, including any other medications they may be taking, when prescribing this formulation.
If you have any questions about this formulation, whether you're a patient or a healthcare provider, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
The formulation of Cyclobenzaprine HCl 1%/Ibuprofen 20% Transdermal Gel is designed to provide targeted treatment for muscle spasms and inflammation. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Together, they provide a potent combination for the treatment of muscle spasms and inflammation.
However, it's important to be aware of potential drug interactions. Cyclobenzaprine HCl can interact with other medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants, and certain anticholinergic drugs. These interactions can increase the risk of serotonin syndrome, a potentially life-threatening condition. If you are taking any of these medications, please consult with your healthcare provider before using this formulation.
Ibuprofen can also interact with certain medications. These include blood thinners, other NSAIDs, corticosteroids, certain antidepressants, certain heart medications, and certain high blood pressure medications. These interactions can increase the risk of serious gastrointestinal (GI) side effects, including bleeding, ulceration, and perforation of the stomach or intestines. If you are taking any of these medications, please consult with your healthcare provider before using this formulation.
It's also important to note that both Cyclobenzaprine HCl and Ibuprofen can interact with alcohol, which can increase the risk of drowsiness and stomach bleeding, respectively. Therefore, it's recommended to avoid or limit alcohol consumption while using this formulation.
Lastly, this formulation is intended for topical use only and should not be ingested or applied to broken skin or open wounds. It should also be kept out of reach of children and pets to prevent accidental ingestion or exposure.
If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to help ensure that you can use this formulation safely and effectively.
The Cyclobenzaprine HCl 1%/Ibuprofen 20% Transdermal Gel is a unique formulation that combines the muscle relaxant properties of Cyclobenzaprine HCl and the anti-inflammatory and analgesic effects of Ibuprofen. This formulation is designed to be applied topically, directly to the skin, where it is absorbed into the underlying tissues to provide targeted relief from pain and inflammation.
Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. When applied topically in a gel form, Cyclobenzaprine HCl can provide targeted relief to specific areas of the body, reducing the systemic side effects often associated with oral administration.
Ibuprofen, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. The topical application allows for the medication to be absorbed directly into the affected area, providing faster and more targeted relief.
The gel is dispensed through a pump mechanism, which allows for easy and precise application. This is particularly beneficial for patients who may have difficulty swallowing pills or who prefer not to take medication orally. The gel-like consistency also makes it easy to apply and allows for the medication to be absorbed quickly and effectively.
By reducing inflammation and relaxing the muscles, it can help to alleviate pain and improve mobility. However, it's important to note that while this formulation can help to manage the symptoms of these conditions, it does not cure them.
If you have any questions about the Cyclobenzaprine HCl 1%/Ibuprofen 20% Transdermal Gel, or if you would like more information about how it works, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy are always here to help.
Cyclobenzaprine HCl 1%/Ibuprofen 20% Transdermal Gel is primarily designed for localized, targeted action on a variety of musculoskeletal conditions. Its key ingredients, Cyclobenzaprine HCl and Ibuprofen, offer both analgesic and muscle relaxing properties making it predominantly used for the management of conditions like muscle sprains, strains, and associated pain. However, there are other potential applications for this formulation that may be considered in certain scenarios.
An illustrative alternate use for the cyclobenzaprine HCl/ibuprofen gel could be for the symptomatic relief of fibromyalgia. Cyclobenzaprine is acknowledged in some studies for its benefits in the management of fibromyalgia symptoms when used systemically, and this topical formulation might provide a localized application alternative. However, clinical evidence supporting this use is limited, and it should be considered only in consultation with a healthcare provider.
This formulation might also be useful in instances of localized inflammatory conditions such as arthritis due to the anti-inflammatory property of ibuprofen. Furthermore, because of the muscle-relaxant effects of cyclobenzaprine, the gel could potentially offer relief with some types of muscular tension headaches, although its use would be off-label and on the advice of a healthcare provider.
For those suffering from certain nerve pain conditions like neuralgias, topical cyclobenzaprine and ibuprofen gel might help manage pain and inflammation on a localized level. The same principle may apply to those who have experienced a shingles outbreak, where postherpetic neuralgia can result in persistent pain long after the initial rash has subsided.
It's important to remember these alternate uses remain largely unproven, and more extensive clinical studies are required to substantiate these claims. This medication like any other should only be used with the guidance of a healthcare professional or a pharmacist trained in compounding. Please consult with your healthcare provider to evaluate if this product is suitable for your unique medical needs.
Should there be any questions or queries about the potential uses or how to use this formulation appropriately, please do not hesitate to reach out to us here at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists are available and ready to assist you with personalized patient care.
The dosage is a semisolid formulation that is dispensed through a pump mechanism. This allows for an easy and precise application of the gel on the skin for the targeted treatment or absorption of the active ingredients.
Transdermal refers to the method of delivery that occurs through the skin. The active ingredients in the gel are absorbed through the skin and into the bloodstream.
The pump mechanism ensures that each dose is measured correctly, helping to avoid under-dosing or overdosing. It also makes the application easier and cleaner, without the need to touch the gel with hands.
The consistency of the gel is semisolid, which is more substantial than a lotion but not as heavy as a cream.
Yes, this formulation provides targeted treatment. By applying it topically to a specific location on the body, the active ingredients can directly affect that area.
The active ingredients in this compounded formulation are Cyclobenzaprine HCl at 1% concentration and Ibuprofen at 20% concentration.
Cyclobenzaprine HCl and Ibuprofen transdermal gel is typically used to relieve pain and inflammation in a specific area of the body such as sore muscles or joints.
Always follow your healthcare professional's instructions when using this gel. Avoid contact with eyes, nose, mouth, and other sensitive areas. Do not apply it to broken, damaged or irritated skin.
Most transdermal gels, including this formulation, have minimal or no odor as they are designed for comfortable daily use without any disturbance.
Store the gel at room temperature, away from heat and direct sunlight. Keep it out of the reach of children and pets. Do not freeze. If the gel changes color, consistency, or develops an odor over time, contact your pharmacist.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)