Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Dapsone
Spironolactone
Niacinamide

Bayview Pharmacy's Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel is a semisolid formulation dispensed through a pump mechanism. This allows for easy and precise application on the skin, targeting conditions such as Acne Vulgaris, Rosacea, Seborrheic Dermatitis, Melasma, and Hyperpigmentation.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Dapsone
Spironolactone
Niacinamide
Topical Gel
6427079ea64324db60518952

Formula Information

A small arrow pointing down

Bayview Pharmacy is pleased to present a specialized topical gel formulation that combines Dapsone 8.5%, Spironolactone 5%, and Niacinamide 2%. This unique blend of medications is designed to address various skin conditions such as acne, rosacea, and seborrheic dermatitis. The gel is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin for targeted treatment or absorption of active ingredients.

Dapsone, an antibacterial agent, works to alleviate inflammation and redness. Spironolactone, an anti-androgen, aids in reducing oil production. Niacinamide contributes to the reduction of inflammation and enhances skin barrier function. Together, these ingredients form a potent treatment for acne, rosacea, and seborrheic dermatitis, helping to reduce inflammation, redness, and oil production, while also improving the skin's barrier function.

Patients may experience mild irritation or dryness when using this formulation. However, these side effects are typically mild and temporary. It is important to note that this formulation is not recommended for use in pregnant or breastfeeding women, as it may potentially harm the fetus or infant. Additionally, this formulation should not be used in patients with a known hypersensitivity to any of the ingredients.

If you have any questions about this formulation or its use in treating acne, rosacea, or seborrheic dermatitis, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is equipped with the knowledge and expertise to assist you.

Drug Interactions

A small arrow pointing down

This compounded formulation of Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel is a semisolid formulation dispensed through a pump mechanism, facilitating easy and precise application on the skin. It is specifically designed for targeted treatment or absorption of active ingredients in a gel-like consistency. The formulation is primarily indicated for the treatment of acne vulgaris, rosacea, and seborrheic dermatitis.

Dapsone acts as an antibacterial agent, reducing the number of Propionibacterium acnes, a bacteria associated with acne. Spironolactone, an anti-androgen, aids in reducing sebum production and inflammation. Niacinamide, an anti-inflammatory agent, assists in reducing redness and irritation.

It is crucial to be aware that this formulation may cause skin irritation, dryness, and redness. Patients are advised to use a mild cleanser and moisturizer to help mitigate these side effects. Additionally, the use of a sunscreen with an SPF of 30 or higher is recommended when using this formulation.

Patients should be closely monitored for signs of hyperkalemia, which can occur with the use of Spironolactone. Similarly, signs of anemia should be watched for, as this can occur with the use of Dapsone. If you have any questions about this formulation or its use, please do not hesitate to reach out.

How Does it Work

A small arrow pointing down

Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel is a unique compounded formulation designed to address various skin conditions. This semisolid formulation is dispensed through a pump mechanism, ensuring easy and precise application on the skin. The gel-like consistency allows for targeted treatment and efficient absorption of the active ingredients.

The formulation combines three potent active ingredients: Dapsone, Spironolactone, and Niacinamide. Dapsone, an antibiotic, works to reduce inflammation and redness. Spironolactone, an anti-androgen, aids in reducing oil production. Niacinamide, a form of Vitamin B3, contributes to the reduction of wrinkles and fine lines. Together, these ingredients work synergistically to alleviate symptoms of acne, rosacea, and other inflammatory skin conditions.

Upon application, the Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel works to reduce inflammation, redness, and oil production, while also minimizing the appearance of wrinkles and fine lines. The gel should be applied to the affected area twice daily, or as directed by your healthcare provider. It is crucial to adhere to the prescribed usage and not exceed the recommended dosage.

Generally, the Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel is well tolerated with rare side effects. However, some individuals may experience skin irritation, redness, or dryness. If any of these side effects occur, it is important to discontinue use and contact your healthcare provider immediately.

If you have any questions about the Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel or how it can help treat your skin condition, please do not hesitate to reach out. We are committed to helping you find the best treatment option tailored to your individual needs.

Other Uses

A small arrow pointing down

This compounded formulation of Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel is a versatile treatment option for a variety of skin conditions. The formulation also offers cosmetic benefits, such as reducing the appearance of wrinkles and fine lines, improving skin texture and tone, and diminishing age spots, sun spots, and other forms of hyperpigmentation. It is also beneficial in reducing the visibility of acne scars, other forms of scarring, and stretch marks. The semisolid formulation is dispensed through a pump mechanism, allowing for easy and precise application on the skin for targeted treatment. If you have any questions about how to use this formulation for any of these conditions, please reach out for further guidance.

Frequently Asked Questions

A small arrow pointing down

What is the Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel?

This is a compounded formulation of three active ingredients: Dapsone, Spironolactone, and Niacinamide. It is a semisolid formulation that is dispensed through a pump mechanism for easy and precise application on the skin.

What is the purpose of the pump mechanism in this formulation?

The pump mechanism facilitates easy and precise application of the gel on the skin.

What is the consistency of this topical gel?

The Dapsone/Spironolactone/Niacinamide topical gel has a gel-like consistency. This makes it easy to apply and allows for targeted treatment or absorption of the active ingredients.

How should I apply this topical gel?

Apply the gel to the affected area as directed by your healthcare provider. The pump mechanism allows for easy and precise application.

What are the active ingredients in this topical gel?

The active ingredients in this topical gel are Dapsone (8.5%), Spironolactone (5%), and Niacinamide (2%).

What is the role of each active ingredient in this formulation?

Dapsone is an antibiotic that is used to treat certain skin conditions. Spironolactone is a medication that can treat fluid retention and hormonal acne, and Niacinamide is a form of Vitamin B3 that can improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness.

Can I use this topical gel for any skin condition?

This topical gel is formulated for specific skin conditions as prescribed by a healthcare provider. It is not intended for use on all skin conditions. Always consult with your healthcare provider before using any new medication.

Are there any side effects associated with this topical gel?

As with any medication, there may be potential side effects. These can include dryness, peeling, redness, or itching at the application site. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

How should I store this topical gel?

Store this topical gel at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Dapsone 8.5%/Spironolactone 5%/Niacinamide 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)