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The Estradiol 0.01%/Hyaluronic Acid 0.2% Vaginal Cream is a specialized semisolid formulation intended for the treatment of atrophic vaginitis and vulvar atrophy, which are common conditions associated with menopause. This cream is compounded to provide a dual-action treatment, with estradiol aiding in the restoration of vaginal tissue health by addressing estrogen deficiency, and hyaluronic acid contributing to hydration and tissue repair. The cream is dispensed in a tube for ease of application, ensuring accurate dosing and targeted relief from the symptoms of vaginal dryness, itching, and irritation. Its formulation is designed to offer a soothing effect while delivering essential medication directly to the affected area.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Estradiol 0.01%/Hyaluronic Acid 0.2% Vaginal Cream is a specially compounded semisolid formulation intended for vaginal administration. This cream is designed to address specific gynecological conditions by delivering a combination of estradiol, a form of estrogen, and hyaluronic acid directly to the vaginal area. The estradiol component is crucial for replenishing estrogen levels, which may be beneficial for postmenopausal women experiencing symptoms of vaginal atrophy, such as dryness, itching, and irritation. By enhancing the estrogenic activity in the vaginal mucosa, this cream can help to restore the thickness and elasticity of the vaginal walls, thereby alleviating discomfort and improving overall vaginal health.
Hyaluronic acid, a naturally occurring polysaccharide, is included in the formulation for its hydrating and viscoelastic properties. It aids in maintaining moisture within the vaginal tissue, which can be particularly helpful for women suffering from vaginal dryness, a common symptom of menopause or other hormonal imbalances. The hyaluronic acid in the cream works synergistically with estradiol to promote tissue repair and provide lubrication, enhancing the comfort and quality of life for the patient.
The cream is dispensed in a tube, allowing for convenient and precise application. This dosage form ensures that the active ingredients are delivered directly to the affected area, maximizing therapeutic effects while minimizing systemic absorption and potential side effects. The formulation is designed to be user-friendly, with the aim of improving patient adherence to the treatment regimen.
For patients and prescribers considering this formulation, it is important to note that the use of hormone therapy, including topical estradiol, should be individualized and based on a thorough evaluation of the potential benefits and risks. Patients with a history of hormone-sensitive cancers, thromboembolic disorders, or unexplained vaginal bleeding should discuss the use of this medication with their healthcare provider. Regular monitoring and follow-up are recommended to assess the efficacy and safety of the treatment.
If you have any questions or require further information about the Estradiol 0.01%/Hyaluronic Acid 0.2% Vaginal Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and support to ensure the best possible outcomes for our patients.
The estradiol 0.01%/hyaluronic acid 0.2% vaginal cream is a compounded medication designed to treat symptoms associated with menopausal changes in the vagina, such as dryness, itching, and burning. Estradiol, a form of estrogen, helps replenish the declining levels of hormones in the body, promoting the maintenance and repair of the vaginal tissues and improving lubrication. Hyaluronic acid is included for its hydrating properties, which can enhance the moisturizing effects of the cream and support tissue healing.
When considering drug interactions, it is important to note that systemic absorption of estradiol from vaginal administration is lower than from oral or transdermal routes, but it can still occur. Therefore, interactions that apply to systemic estrogen therapy should be considered. Estrogens may reduce the metabolism of certain drugs, leading to increased effects or toxicity. These include, but are not limited to, cyclosporine, theophylline, and corticosteroids. Conversely, some drugs can increase the metabolism of estrogens, potentially reducing their effectiveness; these include some anticonvulsants (like phenobarbital and carbamazepine) and some anti-infectives (like rifampicin and rifabutin).
Additionally, estrogens can increase the plasma concentrations of binding proteins, which may affect the levels of other hormones or hormone-based therapies. Patients should be cautious when using other topical products in the vaginal area, as there may be an increased risk of irritation or altered absorption. It is also important to consider the potential for additive effects with other products containing estrogen or those with estrogenic activity, such as certain herbal supplements (e.g., black cohosh, soy isoflavones).
While hyaluronic acid is generally considered safe and has minimal systemic absorption, it is still important to monitor for any signs of local allergic reaction or irritation, especially in patients with a history of sensitivity to hyaluronic acid preparations. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are using to ensure that potential interactions are reviewed and managed appropriately.
For both patients and prescribers, it is crucial to monitor for signs of endometrial hyperplasia or cancer in women with an intact uterus who are using estrogen therapy, as estrogens can increase the risk of these conditions. Progestin therapy should be considered to counteract this risk. Additionally, patients with a history of hormone-sensitive cancers, thromboembolic disorders, or liver disease should use this medication with caution and under close supervision by their healthcare provider.
If you have any questions or require further information regarding potential drug interactions or the appropriate use of this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing you with the necessary guidance to ensure appropriate treatment with this customized medication.
The Estradiol 0.01%/Hyaluronic Acid 0.2% Vaginal Cream is a specialized semisolid formulation that combines two active ingredients, estradiol and hyaluronic acid, to address specific gynecological conditions. This cream is dispensed in a tube, which allows for convenient and precise application to the vaginal area. The formulation is designed to deliver medication directly to the site of action.
Estradiol is a form of estrogen, a hormone that is naturally produced by the ovaries. In this formulation, estradiol works by replenishing estrogen levels in women who are experiencing a deficiency due to menopause or other conditions. This can help alleviate symptoms such as vaginal dryness, itching, and burning, which are often associated with atrophic vaginitis, a condition characterized by thinning and inflammation of the vaginal walls due to decreased estrogen levels. By restoring the estrogen balance, estradiol helps to maintain the health and integrity of the vaginal tissue, promoting comfort and reducing the risk of urinary tract infections and other complications.
Hyaluronic acid is a naturally occurring substance in the body that is known for its hydrating properties and its ability to retain moisture. In the vaginal cream, hyaluronic acid serves as a moisturizing agent, providing additional relief from vaginal dryness. It helps to maintain proper hydration of the vaginal mucosa, which can enhance the natural healing process and provide a protective barrier against irritants and pathogens. The inclusion of hyaluronic acid in this formulation supports the overall health of the vaginal tissue and can improve the elasticity and suppleness of the area, further contributing to comfort during sexual activity and daily life.
The combination of estradiol and hyaluronic acid in this vaginal cream offers a dual approach to treating gynecological conditions related to estrogen deficiency and vaginal dryness. The cream is typically applied according to a prescribed schedule, which may vary depending on the individual needs of the patient. It is important for patients to follow the instructions provided by their healthcare provider to ensure optimal results and to minimize the risk of side effects.
For patients and prescribers considering the use of this formulation, it is essential to understand the specific actions of each ingredient and how they work together to provide relief from symptoms. If you have any questions about the Estradiol 0.01%/Hyaluronic Acid 0.2% Vaginal Cream or its application, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to make informed decisions about your healthcare.
This compounded vaginal cream is primarily used to treat certain symptoms of menopause such as vaginal dryness, itching, and burning. It delivers estradiol, a form of estrogen, directly to the vaginal area to replenish hormone levels, while hyaluronic acid helps to maintain moisture and promote tissue healing.
The cream should be applied as directed by your healthcare provider. Generally, it is applied intravaginally using the applicator provided with the tube. Carefully follow the instructions on the prescription label or as given by your healthcare professional.
Side effects may include vaginal irritation, discharge, or discomfort; headaches; breast tenderness; and bloating. If you experience any severe reactions or side effects, contact your healthcare provider immediately.
It is generally advised to avoid using the cream during menstruation. Wait until your period is finished before resuming use. Consult with your healthcare provider for specific instructions regarding use during your menstrual cycle.
The frequency of use will be prescribed by your healthcare provider and can vary depending on your individual needs and response to the medication.
Improvement in symptoms can occur within a few weeks of consistent use, but it may take longer for full effects to be realized. It is important to continue using the cream as directed, even if symptoms begin to improve.
While the cream can help alleviate vaginal dryness, its primary use is therapeutic rather than as a sexual lubricant. Consult with your healthcare provider if you intend to use it during sexual activity.
The cream should be stored at room temperature, away from moisture and heat. Keep the tube tightly closed when not in use. Follow any specific storage instructions provided by the pharmacy or your healthcare provider.
If you miss a dose, apply the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
This medication should not be used during pregnancy or while breastfeeding unless specifically prescribed by your healthcare provider. If you become pregnant or plan to breastfeed while using the cream, contact your provider for advice.
Before using other vaginal products, check with your healthcare provider or pharmacist. Some products may interfere with the effectiveness of the cream or cause adverse reactions.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert/apply intravaginally
