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Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Estriol
Estradiol

Bayview Pharmacy's Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel is a specially compounded medication. It is dispensed in a pump mechanism for easy and controlled application on the skin. This formulation is designed for localized treatment of conditions such as Vulvovaginal Atrophy, Lichen Sclerosus, Lichen Planus, Genitourinary Syndrome of Menopause, and Dyspareunia.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Estriol
Estradiol
Topical Cream
6427079ea64324177c518ad5

Formula Information

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Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel is a specially compounded medication designed to treat a variety of conditions. This unique formulation combines estriol and estradiol, two hormones naturally produced by the body, in an 80%-20% ratio. The dosage range for this medication is 0.25 - 2.5 mg/Gm.

This topical cream/gel is dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for localized treatment or absorption of active ingredients. Additionally, it can also be used to address skin conditions such as acne, wrinkles, and dryness.

Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel is considered a appropriate treatment option for many patients. However, it is crucial to remember that this formulation should only be used under the supervision of a healthcare provider. Patients are advised to discuss any potential side effects or risks with their healthcare provider before starting this medication.

If you have any questions about Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel or any other compounded medications, please do not hesitate to reach out. We are here to help you find the best treatment option for your individual needs.

Drug Interactions

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This Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel formulation is a semisolid preparation designed for convenient and controlled application on the skin. It is primarily used for the treatment of menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Additionally, it may be prescribed for the treatment of vulvovaginal atrophy, a condition that arises due to decreased estrogen levels in postmenopausal women. This formulation can also be beneficial for premenopausal women suffering from hypoestrogenism, a condition characterized by low levels of estrogen.

It is important to note that this formulation may interact with other medications, including certain antibiotics, antifungals, and anticoagulants. Interactions may also occur with certain herbal supplements, such as black cohosh and red clover. Therefore, it is crucial for patients to inform their healthcare provider of all medications and supplements they are currently taking before starting this treatment.

This formulation is not recommended for use by pregnant or breastfeeding women, or by women who have a history of estrogen-sensitive cancers such as breast cancer or endometrial cancer. Women with a history of blood clots, stroke, or heart attack should also refrain from using this formulation.

Patients are advised to use this formulation strictly as directed by their healthcare provider. In case of any side effects, it is important to contact the healthcare provider immediately. For any further questions or concerns regarding this Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel formulation or its interactions, please consult with your healthcare provider.

How Does it Work

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This compounded formulation of Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel is a semisolid preparation designed for convenient and controlled application on the skin. It is dispensed in a pump mechanism, ensuring precise dosage and ease of use. The cream/gel is primarily used for localized treatment, allowing for direct absorption of the active ingredients into the affected area.

The formulation is a combination of estriol and estradiol, two forms of estrogen, in a ratio of 80%-20%. It is available in strengths of 0.25 - 2.5 mg/gm. This unique blend of hormones is used to treat a variety of conditions, including menopausal symptoms, vaginal atrophy, vulvovaginal atrophy, vulvodynia, lichen sclerosus, and lichen planus.

When applied topically, the cream/gel works by alleviating symptoms such as dryness, itching, burning, and pain. It also helps to reduce inflammation and improve the overall health of the skin. The estriol and estradiol in the formulation help to restore the natural balance of hormones in the body, which can help to reduce symptoms associated with menopause and other conditions.

It is crucial to follow the instructions provided by your healthcare provider when using this formulation. The cream/gel should be applied to the affected area as directed. Avoid contact with the eyes, mouth, and other mucous membranes. If you experience any irritation or other side effects, discontinue use and contact your healthcare provider immediately.

If you have any questions about this formulation or how it works, do not hesitate to reach out. We are here to help you find the best treatment option for your individual needs. Remember, your health and well-being are our top priority.

Other Uses

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This compounded formulation of Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for localized treatment or absorption of active ingredients. This formulation may be used to treat a variety of conditions including vaginal dryness, itching, burning, and irritation. It may also be beneficial in reducing the risk of recurrent urinary tract infections and postmenopausal osteoporosis. Furthermore, it may be used to decrease the risk of endometrial hyperplasia in postmenopausal women who are not taking systemic estrogen. This formulation may also be used to reduce the risk of breast cancer in postmenopausal women and to treat symptoms of premenstrual dysphoric disorder (PMDD). If you have any questions about the use of this formulation for any of these conditions, please reach out for further information.

Frequently Asked Questions

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What is the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

This is a compounded formulation of Estriol and Estradiol, two forms of estrogen, in a semisolid preparation. It is designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

How is the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel dispensed?

The cream/gel is dispensed in a pump mechanism, which allows for easy and controlled application.

How should I apply the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

You should apply the cream/gel to the skin as directed by your healthcare provider. The pump mechanism allows for a controlled amount of the product to be dispensed for each use.

What is the purpose of the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

This product is used for localized treatment or absorption of Estriol and Estradiol, two forms of estrogen. It can be used for various conditions as prescribed by your healthcare provider.

Can I use the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel for any skin condition?

No, this product should only be used as directed by your healthcare provider. It is specifically designed for the treatment or absorption of Estriol and Estradiol.

What are the active ingredients in the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

The active ingredients in this product are Estriol and Estradiol, two forms of estrogen. The formulation contains 80% Estriol and 20% Estradiol.

What should I do if I miss a dose of the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not apply double doses.

Can I use the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel if I am pregnant or breastfeeding?

Consult your healthcare provider before using this product if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this product for these groups has not been fully established.

What should I do if I experience any side effects from the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

If you experience any side effects, contact your healthcare provider immediately. Side effects may include skin irritation, redness, or other reactions at the application site.

How should I store the Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel?

Store this product at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Estriol/Estradiol [80%-20%] 0.25 - 2.5 mg/Gm Topical Cream/Gel
Topical Cream
30 g
controlled

Apply topically to affected area(s)