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Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Slow Release Capsules

FDA-approved generic
Dose form
Slow Release Capsules
Active ingredients
Estriol
Estradiol
Estrone
Progesterone
Testosterone

Bayview Pharmacy's Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Slow Release Capsules are formulated with Methocel E4M, a controlled-release polymer. This formulation is designed to gradually release the encapsulated medication over an extended period, providing sustained therapeutic effects and improved patient compliance. These capsules are used to treat conditions such as Polycystic Ovary Syndrome, Menopause, Hypogonadism, Endometriosis, and Uterine Fibroids.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Estriol
Estradiol
Estrone
Progesterone
Testosterone
Slow Release Capsules
6427079ea64324ca54518ad2

Formula Information

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This formulation is a slow-release capsule that contains a combination of estriol, estradiol, and estrone in an 80%-10%-10% ratio, with dosages ranging from 0.625-2.5 mg. It also includes progesterone in amounts between 50-100 mg, and testosterone ranging from 0.125-2 mg. The capsule is designed to gradually release these hormones over an extended period of time, providing sustained therapeutic effects and improved patient compliance.

Estriol, estradiol, and estrone are naturally occurring hormones that play a crucial role in maintaining reproductive health. Estriol, a weak estrogen, helps alleviate menopausal symptoms such as hot flashes and night sweats. Estradiol, a stronger estrogen, not only reduces menopausal symptoms but also aids in maintaining bone density. Estrone, another form of estrogen, also contributes to reducing menopausal symptoms and preserving bone density.

Progesterone, another hormone included in this formulation, helps regulate the menstrual cycle and alleviate menopausal symptoms. Testosterone, a hormone essential for both men and women, helps maintain muscle mass, bone density, and libido.

This formulation is primarily used to treat menopausal symptoms, hypogonadism, and androgen deficiency. Menopausal symptoms can include hot flashes, night sweats, and vaginal dryness. Hypogonadism is a condition characterized by the body's insufficient production of hormones, leading to potential infertility, decreased libido, and reduced muscle mass. Androgen deficiency, a condition where the body does not produce enough testosterone, can also result in infertility, decreased libido, and reduced muscle mass.

However, it is crucial to note that this formulation should only be used under the supervision of a healthcare provider. If you have any questions or concerns about this formulation, please consult with your healthcare provider.

Drug Interactions

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This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Slow Release Capsules is a comprehensive treatment option for a range of conditions. It is primarily used to manage menopausal symptoms, hypogonadism, and postmenopausal osteoporosis. The formulation contains Estriol, Estradiol, and Estrone, all of which are forms of estrogen. These hormones work synergistically to alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness.

The inclusion of Progesterone in the formulation serves to balance the effects of estrogen, thereby reducing the risk of endometrial cancer. Testosterone, on the other hand, is beneficial for men with hypogonadism, as it helps to enhance libido, energy levels, and muscle mass. This formulation is also beneficial for postmenopausal osteoporosis treatment, as it aids in reducing bone loss and increasing bone density.

It is crucial to note that this formulation is not suitable for use in pregnant or breastfeeding women. Regular monitoring for potential adverse effects such as nausea, vomiting, breast tenderness, or mood changes is recommended. This formulation is designed with Methocel E4M, a controlled-release polymer, which ensures the gradual release of the encapsulated medication over an extended period. This feature offers sustained therapeutic effects, reduces dosing frequency, and improves patient compliance, particularly for medications requiring a controlled and prolonged release profile.

How Does it Work

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This compounded formulation combines the hormones estriol, estradiol, estrone, progesterone, and testosterone in slow-release capsules. The estriol, estradiol, and estrone are present in an 80%-10%-10% ratio, respectively. The progesterone and testosterone are present in a range of 0.625-2.5 mg and 0.125-2 mg, respectively. This formulation is designed to treat a variety of conditions, including menopausal symptoms, endometriosis, and hypogonadism.

The slow-release mechanism of these capsules ensures a gradual and consistent release of hormones into the body. Estriol, estradiol, and estrone, all forms of estrogen, work together to alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Progesterone helps regulate the menstrual cycle and alleviate symptoms of endometriosis. Testosterone, on the other hand, aids in increasing libido, muscle mass, and bone density in men with hypogonadism.

For optimal results, it is crucial to take this formulation as directed by your healthcare provider. Consistency is key, so taking the capsules at the same time each day ensures a steady release of hormones. Additionally, taking the capsules with food aids in proper absorption. If you have any questions or concerns about this formulation, please consult with your healthcare provider.

Other Uses

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This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Slow Release Capsules is designed to offer sustained therapeutic effects over an extended period of time. The formulation is encapsulated with Methocel E4M, a controlled-release polymer, which allows for reduced dosing frequency and improved patient compliance. This formulation can be used to treat a variety of conditions.

For women, it can be used to manage premenstrual dysphoric disorder (PMDD), postmenopausal symptoms, and androgen deficiency. Symptoms of androgen deficiency may include low libido, fatigue, and mood changes. For men, this formulation can be used to treat symptoms of androgen deficiency such as low libido, erectile dysfunction, and fatigue.

Additionally, this formulation can be used to treat symptoms of adrenal insufficiency, which may include fatigue, low blood pressure, and low blood sugar. It can also be used to manage symptoms of hypothyroidism, such as fatigue, weight gain, and depression.

Finally, this formulation can be used to treat symptoms of Turner Syndrome, a genetic disorder that affects women and girls and can cause symptoms such as short stature, infertility, and learning disabilities. If you have any questions about how this formulation can be used to treat any of these conditions, please consult with a healthcare professional.

Frequently Asked Questions

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What is the purpose of the Methocel E4M in these capsules?

Methocel E4M is a type of controlled-release polymer. It is designed to release the encapsulated medication or active ingredient gradually over an extended period of time. This offers sustained therapeutic effects, reduces dosing frequency, and improves patient compliance for medications requiring a controlled and prolonged release profile.

What are the benefits of a slow-release formulation?

Slow-release formulations offer several benefits. They provide sustained therapeutic effects over an extended period, reducing the need for frequent dosing. This can improve patient compliance, particularly for medications that require a controlled and prolonged release profile.

What hormones are included in these capsules?

These capsules contain a compounded formulation of Estriol, Estradiol, Estrone, Progesterone, and Testosterone. The proportions are 80% Estriol, 10% Estradiol, 10% Estrone, with varying amounts of Progesterone and Testosterone.

What is the purpose of the different hormones in this formulation?

Each hormone in this formulation plays a different role in the body. Estriol, Estradiol, and Estrone are types of estrogen, which are important for female reproductive health. Progesterone is also crucial for women's health, particularly in regulating the menstrual cycle and pregnancy. Testosterone, while typically associated with male health, also plays important roles in women's health, including maintaining bone and muscle mass.

How often should I take these capsules?

The frequency of dosing will depend on your specific medical condition and your doctor's instructions. However, the slow-release formulation is designed to reduce the need for frequent dosing.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Always consult your doctor or pharmacist if you are not sure what to do.

Are there any side effects associated with these capsules?

As with any medication, these capsules may have potential side effects. These can vary depending on the individual and the dosage. If you experience any unusual symptoms or side effects, you should contact your healthcare provider immediately.

Can I take these capsules if I am pregnant or breastfeeding?

Always consult your healthcare provider before taking any new medication if you are pregnant or breastfeeding. They will be able to advise you on the potential risks and benefits.

Can I take these capsules with other medications?

Before starting any new medication, you should always inform your healthcare provider about any other medications you are currently taking. This includes prescription medications, over-the-counter drugs, and dietary supplements. They can advise you on any potential interactions.

How should I store these capsules?

Store these capsules in a cool, dry place, away from direct sunlight. Keep them out of reach of children. Do not use the capsules past their expiry date.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Slow Release Capsules
Slow Release Capsules
controlled

Take 1 capsule by mouth