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The Glycolic Acid 20%/Tretinoin 0.1% Topical Cream is a specialized dermatological formulation intended for the treatment of acne, photoaging, and hyperpigmentation. This cream combines the exfoliating properties of glycolic acid with the retinoid activity of tretinoin, promoting skin cell turnover and collagen production. The semisolid preparation is housed in a pump mechanism, ensuring a hygienic, convenient, and controlled application. This delivery system allows for precise dosing and helps to maintain the stability of the active ingredients. The cream is designed for direct application to affected areas of the skin, where it can exert its therapeutic effects locally.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Glycolic Acid 20%/Tretinoin 0.1% Topical Cream is a specially compounded formulation that combines the exfoliating properties of glycolic acid with the retinoid activity of tretinoin. Glycolic acid, an alpha hydroxy acid (AHA), works by gently dissolving the bonds between dead skin cells on the skin's surface, promoting exfoliation and stimulating new cell growth. This action can help to improve skin texture and tone, reduce the appearance of fine lines, and enhance skin brightness. Tretinoin, a derivative of vitamin A, is a potent retinoid that increases cell turnover and collagen production, further aiding in the reduction of wrinkles and improving the overall condition of the skin.
The combination of these two active ingredients in a 20% glycolic acid and 0.1% tretinoin cream provides a powerful treatment for a variety of dermatological conditions. It is particularly beneficial for patients with signs of aging, such as wrinkles and age spots, as well as those with acne-prone skin. The formulation is designed to be used as a localized treatment, with the cream being dispensed from a pump mechanism. This delivery system ensures a controlled application, minimizing waste and ensuring that the correct dose is applied to the skin each time.
Patients should be advised that this formulation may cause skin irritation, especially during the initial phase of treatment. It is important to use sunscreen and limit sun exposure while using this product, as both glycolic acid and tretinoin can increase the skin's sensitivity to the sun. Prescribers should consider the patient's skin type, any existing skin conditions, and their overall treatment goals when recommending this compounded cream. It is also essential to monitor the patient's progress and adjust the treatment regimen as necessary to achieve the best results with minimal side effects.
For optimal outcomes, patients should follow the specific usage instructions provided by their healthcare provider, which typically include applying the cream to clean, dry skin, usually once daily in the evening or as directed. It is important to start with a lower frequency of application to allow the skin to adjust before increasing to daily use. Patients should also be aware that improvements may take several weeks to become noticeable.
If you have any questions or require further information about the Glycolic Acid 20%/Tretinoin 0.1% Topical Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and prescribers to ensure the safe and appropriate use of this formulation.
However, it is important to consider potential drug interactions when using this topical cream formulation. Glycolic acid, an alpha hydroxy acid (AHA), enhances skin exfoliation and may increase the penetration of tretinoin, a retinoid, potentially leading to increased efficacy but also a higher risk of irritation. Patients should be advised to monitor for signs of excessive skin irritation, such as redness, peeling, or discomfort, and to adjust the frequency of application or discontinue use as necessary.
Concurrent use of other topical acne treatments, particularly those with peeling, exfoliating, or drying effects (such as benzoyl peroxide, salicylic acid, or sulfur) may increase the likelihood of skin irritation. It is advisable to avoid using these agents together or to use them at different times of the day. Additionally, products containing alcohol or astringents may exacerbate skin dryness or irritation and should be used with caution.
Patients should also be aware of the potential for increased photosensitivity when using this formulation. Tretinoin can make the skin more susceptible to sunburn. The use of effective sun protection, including broad-spectrum sunscreen and protective clothing, is essential, especially during peak sunlight hours. Concurrent use of medications known to cause photosensitivity, such as certain antibiotics (e.g., tetracyclines, fluoroquinolones), thiazide diuretics, and sulfonylureas, may further increase this risk.
It is important to note that the use of cosmetics or products with a high concentration of alcohol, spices, lime, menthol, or cinnamon should be avoided, as these can cause skin irritation when used with glycolic acid and tretinoin. Patients should also be cautious when using other skin care products that are abrasive or may have drying effects, including medicated or abrasive soaps and cleansers, soaps and cosmetics with a strong drying effect, and products with high concentrations of alcohol, astringents, spices, or lime.
Systemic absorption of tretinoin is minimal; however, if the patient is taking other systemic retinoids (such as isotretinoin for acne), the risk of hypervitaminosis A or retinoid syndrome could theoretically be increased. Although this is unlikely with topical application, it is still important to consider all sources of vitamin A to avoid potential toxicity.
Lastly, caution should be exercised when using this formulation in patients who are pregnant or breastfeeding. Tretinoin is a known teratogen, and while systemic absorption is low with topical application, the safety of its use during pregnancy has not been established. It is recommended to consult with a healthcare provider before using this product if the patient is pregnant, planning to become pregnant, or breastfeeding.
For any further questions or concerns regarding the use of this glycolic acid 20%/tretinoin 0.1% topical cream, or to report any adverse effects or interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure safe and appropriate use of this formulation.
Glycolic Acid 20%/Tretinoin 0.1% Topical Cream is a specially formulated dermatological preparation that combines the exfoliating properties of glycolic acid with the retinoid activity of tretinoin. This cream is designed to be dispensed in a semisolid form through a pump mechanism, which ensures a hygienic, convenient, and controlled application. The pump allows for precise dosing and minimizes the degradation of active ingredients by limiting their exposure to air and light.
Glycolic acid, an alpha hydroxy acid (AHA), works primarily by exfoliating the uppermost layers of the skin. It dissolves the bonds between dead skin cells, allowing them to be sloughed away more easily, revealing fresher, smoother skin beneath. This action helps to unclog pores, reduce the appearance of fine lines, and improve overall skin texture. It also promotes hydration and may help other skincare ingredients penetrate more deeply.
Tretinoin, a derivative of vitamin A, is a potent retinoid that affects the behavior of skin cells. It works by increasing cell turnover, stimulating collagen production, and reducing the cohesiveness of follicular epithelial cells, which helps prevent the formation of comedones (blackheads and whiteheads). Tretinoin at a 0.1% concentration is considered a strong formulation.
When combined, glycolic acid and tretinoin act synergistically to enhance the treatment of various skin conditions, such as acne, photoaging, and hyperpigmentation. The glycolic acid's exfoliating action allows tretinoin to penetrate more effectively, potentially increasing its efficacy. However, this combination can also increase skin sensitivity, so it is important to use it under the guidance of a healthcare professional. Patients should be advised to use sunscreen and limit sun exposure while using this formulation to prevent sun damage.
It is important for both patients and prescribers to understand that this formulation may cause initial skin irritation, redness, or peeling, which typically improves as the skin adjusts to the treatment. The cream should be applied to clean, dry skin, usually once daily in the evening or as directed by a healthcare provider. Patients should start with a lower frequency of application to assess skin tolerance before gradually increasing to daily use if appropriate.
For any questions or concerns regarding the use of Glycolic Acid 20%/Tretinoin 0.1% Topical Cream, or to discuss individual patient needs, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this formulation.
This topical cream is used for the treatment of various skin conditions such as acne, photoaging, hyperpigmentation, and fine wrinkles. It combines glycolic acid, which exfoliates the skin, with tretinoin, which is a form of vitamin A that promotes skin cell turnover.
Apply a small amount of the cream to the affected areas of the skin once daily before bedtime, or as directed by your dermatologist. Use the pump mechanism to dispense the cream, which allows for controlled application. Avoid contact with eyes, mouth, angles of the nose, and mucous membranes. Wash your hands after applying the cream.
It is recommended to use this cream at night due to increased sensitivity of the skin to sunlight after application. If you have to use it during the day, apply a broad-spectrum sunscreen and wear protective clothing to safeguard your skin from sun damage.
Common side effects may include dryness, redness, peeling, or irritation at the site of application. If these symptoms persist or worsen, contact your healthcare provider. More serious side effects are rare but can occur, especially with excessive use or sensitivity to the active ingredients.
The cream should be stored at room temperature away from direct sunlight and heat. Do not freeze it. Keep the container tightly closed, and ensure that the pump is locked to prevent accidental dispensing or contamination.
Yes, you can apply makeup after the cream has been fully absorbed. However, wait for a significant amount of time, usually around 20-30 minutes, before applying any additional products on top of the cream to ensure effectiveness and reduce the potential for interaction.
Improvements may be noticed within a few weeks of consistent use, but it can take several months to see the full benefits. It is important to use the cream regularly and as directed by your physician.
This formulation may not be suitable for every skin type, especially for those with very sensitive or easily irritated skin. It's best to consult with a dermatologist who can advise whether this particular combination of glycolic acid and tretinoin is appropriate for your skin.
Yes, the cream can be applied to the entire face if prescribed for that purpose, but it should be used with caution. Avoid applying near the eyes, mouth, and other mucous membranes. It is also important to start with a small amount to see how your skin reacts and follow the guidance of your healthcare provider.
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Be cautious when using other topical treatments in combination with this cream. Some products may increase irritation or have adverse interactions. Always consult your dermatologist before adding new products to your skin care regimen.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
