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The Lidocaine 5%/Prilocaine 5% Topical Cream is a compounded semisolid preparation that combines two local anesthetics for potent synergistic effects. This cream is specifically formulated for topical use and is dispensed in a pump mechanism container, which allows for convenient, controlled, and hygienic application directly to the skin. The dual-action formula is designed to provide localized relief from pain and discomfort associated with various dermatological procedures and conditions.
This topical anesthetic cream is commonly used to numb the skin before minor surgical procedures, such as needle insertions, superficial skin surgeries, and laser treatments. Additionally, it can be used to alleviate discomfort from minor burns, insect bites, and other minor skin irritations.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Lidocaine 5%/Prilocaine 5% Topical Cream is a compounded medication that combines two local anesthetics, lidocaine and prilocaine, each at a concentration of 5%. This cream is formulated to provide topical anesthesia by temporarily numbing the surface of the skin. The mechanism of action for both lidocaine and prilocaine involves blocking sodium channels, which are necessary for the initiation and conduction of neuronal impulses. When applied to the skin, this cream can prevent the generation and transmission of nerve impulses, leading to a loss of sensation in the area of application.
The semisolid preparation of this cream is specifically designed to be dispensed in a pump mechanism. This delivery system allows for convenient, hygienic, and controlled application, ensuring that the correct dose is administered each time. The pump mechanism also helps to prevent contamination of the product, which is particularly important for maintaining the integrity of the active ingredients.
This formulation is commonly used for a variety of dermatological procedures and conditions that require localized anesthesia. Additionally, it can be used to alleviate pain from conditions like chronic neuropathic pain, post-herpetic neuralgia, and other painful skin disorders. The cream's onset of action typically occurs within 30 to 60 minutes after application, with a duration of action that can last for 1 to 2 hours, depending on the site of application and individual patient factors.
Patients and prescribers should be aware that the use of Lidocaine 5%/Prilocaine 5% Topical Cream may be contraindicated in individuals with a known hypersensitivity to local anesthetics of the amide type or to any other component of the product. Caution is also advised in patients with certain medical conditions such as methemoglobinemia, severe hepatic disease, or in those taking certain medications that may interact with local anesthetics. It is important to apply the cream as directed, avoiding application to broken or inflamed skin, and to adhere to the recommended dosage and duration of use to minimize the risk of systemic toxicity.
For any questions regarding the use of Lidocaine 5%/Prilocaine 5% Topical Cream, or to discuss individual patient needs and considerations, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and is available to support both patients and prescribers with expert advice and information on this and other compounded medications.
Lidocaine and prilocaine, the active ingredients in this topical cream, are both local anesthetics that work by blocking nerve signals in your body. When applied to the skin, this combination can provide localized pain relief by numbing the area. This formulation is commonly used for procedures that may cause discomfort on the skin, such as needle insertions, minor surgical procedures, or other dermatological treatments. It is also used to treat conditions like neuropathic pain or as part of a pain management regimen for certain chronic conditions.
When considering the use of this lidocaine/prilocaine topical cream, it is important to be aware of potential drug interactions. Since both lidocaine and prilocaine are metabolized in the liver, drugs that affect liver enzymes, particularly those that inhibit cytochrome P450 isoenzymes, may potentially increase the levels of lidocaine and prilocaine, leading to an increased risk of systemic toxicity. Examples of such drugs include cimetidine, beta-blockers like propranolol, and certain antifungal agents like ketoconazole.
Concomitant use of other local anesthetics or medications with a similar mechanism of action should be approached with caution, as the systemic toxic effects may be additive. This is particularly important in patients receiving multiple local anesthetic procedures or those applying the cream over a large surface area of the skin.
Patients who are on class III antiarrhythmic drugs, such as amiodarone, should also be monitored closely, as the risk of additive cardiac effects could be significant. Methemoglobinemia is a rare but serious condition associated with both lidocaine and prilocaine. Drugs that induce methemoglobinemia, such as sulfonamides, acetaminophen, and nitrates, may increase this risk when used concurrently with this topical cream.
It is also important to consider the physical interactions between the cream and other topical agents. The formulation of this cream may alter the absorption of other concurrently applied topical medicines, which could either increase their absorption and potential toxicity or decrease their efficacy.
Patients should be advised to inform their healthcare provider of all medications they are taking, including prescription drugs, over-the-counter medications, and herbal supplements, before starting treatment with lidocaine/prilocaine cream. Additionally, patients should be instructed to use the cream as directed and to avoid applying it to larger areas or for longer durations than prescribed, as this may increase the risk of systemic absorption and potential drug interactions.
If you have any questions or concerns regarding the use of this lidocaine/prilocaine topical cream or its potential interactions with other medications, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and guidance you need to ensure appropriate treatment.
Lidocaine 5%/Prilocaine 5% Topical Cream is a compounded medication that combines two local anesthetics, lidocaine and prilocaine, each at a concentration of 5%. This cream is designed to provide localized pain relief by numbing the skin and the tissues just beneath the skin. When applied to the affected area, the active ingredients work by blocking the sodium channels in the neuronal cell membranes. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing effect and reducing the sensation of pain.
The formulation is presented in a semisolid state, which allows for easy application and adherence to the skin surface. The cream is dispensed from a pump mechanism, which offers several advantages. Firstly, it ensures a controlled and consistent dose with each application, which is crucial for maintaining the efficacy and safety of the medication. Secondly, the pump design minimizes the risk of contamination, as it prevents direct contact with the contents of the container. Lastly, the pump mechanism provides convenience for the patient, allowing for easy self-administration without the need for additional tools or assistance.
This topical cream is particularly useful in treating various disease states that involve localized pain or the need for superficial anesthesia. It is commonly used for procedures such as needle insertions, minor surgical interventions, and the treatment of conditions like chronic neuropathic pain or inflammatory skin disorders.
The cream should be applied as directed by a healthcare professional, and the area of application should be limited to the recommended size to avoid systemic absorption, which could lead to adverse effects. Additionally, patients should be advised not to apply the cream to broken or inflamed skin unless directed by a healthcare provider, as this could increase systemic absorption.
For any questions regarding the use of Lidocaine 5%/Prilocaine 5% Topical Cream, or to discuss the suitability of this formulation for a specific patient or condition, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.
Lidocaine 5%/Prilocaine 5% Topical Cream is used to provide localized relief from pain by numbing specific areas of the skin. It is often applied before minor skin procedures, such as needle insertions, to reduce discomfort.
Apply the cream as directed by your doctor or pharmacist. Use the pump mechanism to dispense the cream onto the skin and spread it evenly over the treatment area.
The frequency of application will depend on your physician’s instructions. Do not exceed the recommended dose or frequency to avoid possible side effects.
No, you should not apply Lidocaine 5%/Prilocaine 5% Topical Cream to open wounds or damaged skin. It is intended for use only on intact skin.
Possible side effects include mild skin reactions such as redness or slight burning at the application site. If you experience any severe reactions or signs of an allergic reaction, such as swelling or difficulty breathing, seek medical attention immediately.
It typically takes about 30 to 60 minutes for the numbing effect to begin after application. Consult with your healthcare provider regarding the onset of action for your specific treatment.
Food intake does not affect the action of Lidocaine 5%/Prilocaine 5% Topical Cream. You can apply it before or after meals, according to the timing suggested by your healthcare provider.
Use in children should be under the supervision of a physician. Dosage and application will be determined based on the child’s age, weight, and the treatment area.
If you miss a scheduled application, apply the cream as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
You may be advised to cover the treatment area with an occlusive dressing to enhance absorption, but this should only be done under the direction of a healthcare professional. Uncovered application is generally sufficient for most patients.
Store the cream at room temperature, away from direct heat and light. Keep the container closed when not in use, and keep it out of reach of children and pets.
Always consult with your healthcare provider before using any medications, including Lidocaine 5%/Prilocaine 5% Topical Cream, if you are pregnant or breastfeeding to ensure safety for you and your baby.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
