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Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Metformin Hydrochloride
Spironolactone
Progesterone

Bayview Pharmacy's Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel is a semisolid formulation dispensed through a pump mechanism. This allows for easy and precise application on the skin, facilitating targeted treatment or absorption of active ingredients. It is used to treat conditions such as Polycystic Ovary Syndrome, Acne, Hirsutism, Hyperandrogenism, and Menopausal Symptoms.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Metformin Hydrochloride
Spironolactone
Progesterone
Topical Gel
6427079ea643241f82518dcb
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy is pleased to present a specially compounded topical gel formulation of Metformin HCl 5%, Spironolactone 5%, and Progesterone 1%. This unique formulation is specifically designed to address various skin conditions such as acne, rosacea, and seborrheic dermatitis.

Metformin HCl is an antihyperglycemic agent that works by reducing the production of sebum, a key factor in the development of acne. Spironolactone, an antiandrogen, aids in decreasing the production of androgens, hormones that can trigger acne and other skin conditions. Progesterone, a naturally occurring hormone, helps to alleviate inflammation and redness associated with various skin conditions.

It is designed to reduce inflammation, redness, and the production of sebum and androgens. Moreover, it provides a appropriate treatment alternative for patients who are unable to take oral medications.

The gel is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. This targeted treatment facilitates the absorption of active ingredients in a gel-like consistency, ensuring optimal results.

If you have any questions about this unique formulation or how it can help manage your skin condition, please do not hesitate to contact us at Bayview Pharmacy. Our team is committed to helping you find the most suitable treatment option for your specific needs.

Drug Interactions

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Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel is a compounded formulation designed for targeted treatment of acne, hirsutism, and androgenic alopecia. This unique combination of active ingredients is dispensed in a semisolid gel-like consistency through a pump mechanism, ensuring easy and precise application on the skin.

Metformin HCl, an oral antihyperglycemic agent, is typically used to treat type 2 diabetes mellitus. In this formulation, it may help to reduce blood glucose levels, potentially impacting the severity of acne. Spironolactone, an aldosterone antagonist, is commonly used to treat hypertension, edema, and hirsutism. It may help to reduce blood pressure and the severity of hirsutism. Progesterone, a hormone, is used to treat premenstrual syndrome, endometriosis, and menopausal symptoms. It may help to alleviate these conditions when applied topically.

Patients should be aware that potential side effects of Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel may include nausea, vomiting, diarrhea, dizziness, headache, and fatigue. Spironolactone may cause hyperkalemia, and Progesterone may cause breast tenderness, bloating, and mood swings.

Prescribers should be cognizant of potential interactions between Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel and other medications. These may include diuretics, ACE inhibitors, and nonsteroidal anti-inflammatory drugs. Spironolactone may interact with potassium-sparing diuretics, and Progesterone may interact with anticoagulants.

If you have any questions about Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel, please do not hesitate to reach out for further information.

How Does it Work

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Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel is a specially compounded medication designed to address various skin conditions. This unique formulation combines the anti-inflammatory and sebum-reducing properties of Metformin HCl, an anti-diabetic medication, with Spironolactone, an anti-androgen known for its ability to reduce sebum production and acne appearance. Additionally, Progesterone, a hormone, is included for its inflammation-reducing and acne appearance minimizing effects.

When applied topically, this gel works to target and reduce inflammation, sebum production, and acne appearance. However, it is crucial to avoid using this medication on broken or irritated skin. It is also not recommended for use on the face or other sensitive body areas due to the potency of the active ingredients.

For optimal results with Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel, it is essential to adhere to the usage instructions provided by your healthcare provider. Typically, the medication should be applied to the affected skin area twice daily or as directed by your healthcare provider. Care should be taken to avoid contact with the eyes, mouth, and other sensitive body areas during application.

If you have any queries or concerns regarding the use of Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel, please do not hesitate to contact us at Bayview Pharmacy.

Other Uses

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This compounded formulation of Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel is a semisolid preparation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring targeted treatment or absorption of the active ingredients. The gel-like consistency of the formulation enhances its absorption and effectiveness.

Traditionally, this formulation has been used in the treatment of Polycystic Ovary Syndrome, Acne, Hirsutism, Hyperandrogenism, and Menopausal Symptoms. However, its use is not limited to these conditions. It may also be employed in the management of endometriosis, premenstrual dysphoric disorder, and postmenopausal vaginal atrophy.

Furthermore, this formulation may be used as a preventive measure against endometrial hyperplasia, a condition that can lead to endometrial cancer. It may also be used to reduce the risk of breast cancer in postmenopausal women. As with any medication, it is crucial to discuss the potential risks and benefits with your healthcare provider before starting treatment.

If you have any questions about this formulation or any other medication, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to provide you with the information and support you need to make informed decisions about your health.

Frequently Asked Questions

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What is the Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel?

This is a compounded formulation of three active ingredients: Metformin HCl, Spironolactone, and Progesterone. It is a semisolid formulation that is dispensed through a pump mechanism for easy and precise application on the skin.

How does the pump mechanism work?

The pump mechanism allows for easy and precise application of the gel on the skin. It dispenses a controlled amount of the gel, ensuring that you get the right dosage each time.

What is the consistency of this gel?

The gel has a semisolid, gel-like consistency that allows for easy application and absorption into the skin.

How should I apply this gel?

You should apply this gel directly to the skin as directed by your healthcare provider. The pump mechanism allows for easy and precise application.

What are the active ingredients in this gel?

The active ingredients in this gel are Metformin HCl, Spironolactone, and Progesterone. These ingredients are combined in a compounded formulation for targeted treatment.

What is the purpose of each active ingredient in this gel?

Metformin HCl is commonly used to control high blood sugar in people with type 2 diabetes. Spironolactone is used to treat high blood pressure and heart failure, and to diagnose and treat conditions that cause too much aldosterone in the body. Progesterone is used to regulate the menstrual cycle and treat conditions such as abnormal uterine bleeding.

Can I use this gel if I am pregnant or breastfeeding?

Before using this gel, you should discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Some of the active ingredients may have potential risks during pregnancy or breastfeeding.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What are the potential side effects of this gel?

Side effects can vary depending on the individual and the dosage. Common side effects may include skin irritation or rash. If you experience any severe or persistent side effects, you should contact your healthcare provider immediately.

How should I store this gel?

This gel should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Metformin HCl 5%/Spironolactone 5%/Progesterone 1% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Once daily