Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Metronidazole 2% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Metronidazole

Metronidazole 2% Topical Cream is a semisolid preparation formulated for direct application to the skin. This cream is dispensed through a pump mechanism, which allows for convenient and controlled dosing. The active ingredient, metronidazole, is utilized for its antimicrobial and anti-inflammatory properties. This formulation is specifically designed to treat a variety of dermatological conditions, including rosacea, which is characterized by redness and pimples on the face, and other inflammatory lesions caused by certain bacteria. The cream's consistency ensures that it is easily spreadable, facilitating targeted treatment and absorption directly at the site of infection or inflammation.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Metronidazole
Topical Cream
65bbf6d03991019e1def2978

Formula Information

A small arrow pointing down

Metronidazole 2% Topical Cream is a specially formulated medication designed to treat a variety of skin conditions. As a semisolid preparation, it is dispensed in a pump mechanism that allows for convenient and controlled application directly to the affected areas of the skin. This delivery system ensures that the medication is applied evenly and reduces the risk of contamination that can occur with jar-based creams.

When applied topically, it is primarily used to treat skin conditions such as rosacea, which is characterized by inflammation and redness. Metronidazole works by inhibiting the growth of certain bacteria and protozoa, thereby reducing inflammation and the number of lesions. It is also used off-label for other dermatological conditions that may benefit from its anti-inflammatory and antimicrobial properties.

For patients, it is important to use Metronidazole 2% Topical Cream as directed by a healthcare provider. The cream should be applied to clean, dry skin, usually in a thin layer. Patients should be advised to avoid contact with the eyes and mouth, and to wash their hands before and after application. It is also important to use the medication for the full prescribed duration, even if symptoms improve before the treatment course is complete, to prevent the recurrence of infection.

Prescribers should consider Metronidazole 2% Topical Cream for patients with rosacea or other indicated skin conditions that may benefit from topical antibiotic therapy. The pump mechanism of this formulation can improve patient adherence to the treatment regimen by providing a simple and hygienic method of application. Additionally, prescribers should monitor patients for potential side effects, such as skin irritation or dryness, and adjust treatment as necessary.

If you have any questions about Metronidazole 2% Topical Cream or its use in treating skin conditions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive information and support to both patients and healthcare providers to ensure the safe and appropriate use of our formulations.

Drug Interactions

A small arrow pointing down

Metronidazole 2% Topical Cream is an antimicrobial agent used for the treatment of certain skin conditions such as rosacea, which is characterized by redness and pimples on the face. When using this topical formulation, it is important to consider potential drug interactions, although systemic absorption is generally low with topical application. However, interactions can still occur, particularly with other topical agents or if the cream is used over large surface areas of the skin for prolonged periods.

Concomitant use of metronidazole with anticoagulants like warfarin may potentiate the anticoagulant effect, leading to an increased risk of bleeding. Patients should be monitored for signs of bleeding and coagulation parameters should be checked more frequently. Additionally, alcohol or products containing propylene glycol should be avoided during and for at least 24 hours after the use of metronidazole due to the possibility of a disulfiram-like reaction, which can include symptoms such as abdominal cramps, nausea, vomiting, headaches, and flushing.

While the use of other topical agents in conjunction with metronidazole 2% Topical Cream is not generally contraindicated, caution is advised. The use of abrasive cleansers, tinctures, astringents, products containing alcohol or acetone, and other irritant or drying agents may lead to increased skin irritation. It is recommended to consult with a healthcare provider before combining such products with metronidazole topical therapy.

Patients should also be advised to avoid exposure to sunlight or ultraviolet light, such as tanning beds, as metronidazole can make the skin more sensitive to UV radiation, increasing the risk of sunburn. If patients require the use of other dermatological medications or have a history of blood dyscrasia, they should inform their healthcare provider before starting treatment with metronidazole 2% Topical Cream.

It is essential for patients to inform their healthcare providers of all medications they are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, to ensure that there are no potential interactions with metronidazole 2% Topical Cream. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

A small arrow pointing down

Metronidazole 2% Topical Cream is a specially formulated medication that is designed to treat certain skin conditions such as rosacea, which is characterized by redness and pimples on the face. The active ingredient, metronidazole, is an antibiotic and antiprotozoal medication that works by targeting the DNA of the bacteria and protozoa causing the infection, disrupting their ability to reproduce and repair themselves. This action helps to reduce inflammation and the number of lesions, leading to an improvement in symptoms.

The cream is compounded into a semisolid preparation that is dispensed from a pump mechanism. This type of delivery system is chosen for its convenience and ability to provide a controlled amount of medication with each use. When the pump is pressed, a measured dose of the cream is released, which can then be applied directly to the affected area of the skin. The base of the cream is designed to ensure that the metronidazole is absorbed into the skin where it can exert its therapeutic effects locally.

For patients, it is important to use the medication as directed by a healthcare provider. The area of application should be clean and dry before the cream is applied. Patients should wash their hands before and after applying the cream to avoid spreading the infection or getting the medication in their eyes or mouth. Consistent use as prescribed is crucial for the effectiveness of the treatment.

It is important to diagnose the condition accurately and consider any potential interactions with other medications the patient may be using. Additionally, prescribers should inform patients about potential side effects, which may include skin irritation, dryness, or a metallic taste in the mouth if the cream is applied near the lips.

At Bayview Pharmacy, we are committed to providing high-quality compounded medications tailored to the needs of our patients. Our team of compounding pharmacists is available to answer any questions or concerns you may have about Metronidazole 2% Topical Cream or any other formulations. Please do not hesitate to reach out to us for further information or guidance.

Other Uses

A small arrow pointing down

While Metronidazole 2% Topical Cream is commonly known for its efficacy in treating certain dermatological conditions such as rosacea, it may have other potential uses that extend beyond this primary indication. As compounding pharmacists, we recognize that, occasionally, such formulations are utilized off-label for similar inflammatory skin disorders where the antimicrobial and anti-inflammatory properties of metronidazole could be beneficial. For instance, patients suffering from perioral dermatitis, which presents with rash and bumps around the mouth, have found relief with the application of metronidazole topical formulations. Additionally, it has been considered for use in wound care, particularly for its antimicrobial effects in preventing or managing bacterial colonization and infection in minor skin wounds.

Moreover, some studies suggest that metronidazole's anti-inflammatory action might assist in the management of mild to moderate acne, although it is not a first-line treatment and should only be considered when traditional treatments are not suitable or have failed. Furthermore, there are anecdotal reports of its use in seborrheic dermatitis due to its anti-inflammatory properties, although this is not a widely accepted practice and more research is needed to support this use. An advantage of this particular formulation being dispensed in a pump mechanism is the ease of application and the ability to deliver a consistent dose, which is particularly important for maintaining the effectiveness of the treatment regimen and minimizing the risk of potential resistance development when treating infectious conditions.

It is critical to note that off-label uses of metronidazole cream should be pursued with caution and under the guidance of a healthcare professional. The effectiveness and safety for uses other than those approved by regulatory bodies have not been established. Prescribers considering this formulation for unapproved indications should monitor patient outcomes closely and adjust treatment as necessary. Patients interested in exploring the potential additional benefits of Metronidazole 2% Topical Cream should do so in consultation with a healthcare provider.

If you have any questions about the potential off-label uses of Metronidazole 2% Topical Cream or need further information, please reach out to us at Bayview Pharmacy. Our team is well-equipped to provide comprehensive information, guidance, and support for both patients and prescribers considering this formulation for alternative uses.

Frequently Asked Questions

A small arrow pointing down

What is Metronidazole 2% Topical Cream used for?

Metronidazole 2% Topical Cream is primarily used to treat certain inflammatory skin conditions such as rosacea. It effectively reduces redness, swelling, and the number of pimples caused by the condition. It may also be prescribed for other skin infections as determined by your healthcare provider.

How should I use Metronidazole 2% Topical Cream?

Apply a thin layer of Metronidazole 2% Topical Cream to the affected area as directed by your healthcare provider. It is typically applied once or twice a day. To use the pump mechanism, simply press down to dispense the cream, and then spread it gently on your skin.

What are the benefits of the pump mechanism?

The pump mechanism provides a convenient and controlled way to dispense the cream, which helps to ensure consistent dosing and minimizes waste. It also helps to maintain the product's hygiene by preventing direct contact with the contents of the container.

Can I use Metronidazole 2% Topical Cream for acne?

Metronidazole 2% Topical Cream is not generally used to treat common acne. It is specifically indicated for skin conditions such as rosacea. Always consult your healthcare provider to determine if this cream is appropriate for your particular skin condition.

Are there any side effects associated with Metronidazole 2% Topical Cream?

Possible side effects include skin irritation, dryness, redness, metallic taste, tingling or numbness of extremities, and nausea. If you experience any severe side effects or signs of an allergic reaction, such as difficulty breathing or swelling of the face, seek medical attention immediately.

How long should I use Metronidazole 2% Topical Cream?

The duration of treatment with Metronidazole 2% Topical Cream will depend on the condition being treated and your response to the medication. Follow your healthcare provider’s instructions precisely. Do not use it for a longer period than prescribed as this can lead to increased side effects without improving the condition.

Can I apply makeup over Metronidazole 2% Topical Cream?

You may apply makeup over the Metronidazole 2% Topical Cream once it is fully absorbed into your skin. However, it is advisable to use non-comedogenic and non-irritating makeup to prevent worsening your skin condition.

Should I avoid any activities or products while using this cream?

While using Metronidazole 2% Topical Cream, you should avoid exposure to sunlight or artificial UV light, such as tanning beds, as metronidazole can make your skin more sensitive to sunlight. Also, avoid using other potentially irritating products on the skin, unless otherwise directed by your healthcare provider.

Will Metronidazole 2% Topical Cream cure my skin condition?

Metronidazole 2% Topical Cream can help manage the symptoms of skin conditions like rosacea by reducing inflammation and redness, but it is not considered a cure. Rosacea is a chronic condition, and long-term management with medication and lifestyle changes is often necessary.

What should I do if I miss a dose?

If you miss a dose of Metronidazole 2% Topical Cream, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular application schedule. Do not apply extra cream to make up for the missed dose.

Is Metronidazole 2% Topical Cream safe to use during pregnancy or breastfeeding?

The safety of Metronidazole 2% Topical Cream during pregnancy or breastfeeding has not been fully established. Consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or are breastfeeding.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Metronidazole 2% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)