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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository

FDA-approved generic
Dose form
Suppository
Active ingredients
Morphine Sulfate
Metoclopramide Hydrochloride

The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication. This solid dosage form is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication. It is used for the treatment of chronic pain, nausea, vomiting, gastroparesis, and dyspepsia, providing local or systemic absorption.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Morphine Sulfate
Metoclopramide Hydrochloride
Suppository
6427079ea643246d20518ec1
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication that combines two active ingredients to provide relief from pain and nausea. Morphine Sulfate, an opioid analgesic, works by blocking pain signals from reaching the brain. Metoclopramide, a dopamine antagonist, aids in reducing nausea and vomiting.

This suppository is a solid dosage form that is inserted into a body cavity, typically the rectum, where it dissolves or melts to release the medication for local or systemic absorption. It is easy to administer and provides fast-acting relief. The Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is available in various strengths and can be used in both adults and children. The dosage should be adjusted according to the patient's individual needs.

It is important to note that this medication should not be used for more than five consecutive days. Additionally, it should not be used in combination with other opioid medications due to the risk of potential interactions. Always consult with a healthcare professional before starting any new medication regimen.

If you have any questions about the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository or how it can be used to treat your condition, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to help you find the best treatment option for your needs.

Drug Interactions

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded formulation designed for the management of nausea and vomiting symptoms often associated with chemotherapy, radiation therapy, and postoperative recovery. The suppository is a solid dosage form that is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

The medication combines the effects of Morphine Sulfate, an opioid agonist that acts on the central nervous system to alleviate pain, and Metoclopramide, a dopamine antagonist that enhances gastric motility and reduces nausea and vomiting.

Patients should be aware that this medication may cause side effects such as drowsiness, dizziness, and confusion. It is advised not to drive or operate machinery until the effects of the medication are fully understood. This medication may also cause constipation, hence it is recommended to maintain adequate hydration and a high-fiber diet. Additionally, this medication may cause an increase in blood pressure, thus regular monitoring is advised.

It is important to note that this medication may interact with other medications, including anticholinergics, antihistamines, and other opioids. Patients should inform their healthcare provider of all medications they are currently taking before using this medication.

Healthcare providers should exercise caution when prescribing this medication to patients with a history of substance abuse or mental illness due to the potential side effects of drowsiness, dizziness, and confusion. Regular monitoring of the patient's blood pressure is also recommended due to the potential for increased blood pressure.

If you have any questions about this medication or its interactions, please do not hesitate to reach out for further information.

How Does it Work

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded medication designed to alleviate moderate to severe pain, as well as nausea and vomiting. This combination medication works by utilizing the pain-blocking properties of morphine sulfate, which prevents pain signals from reaching the brain, and the action of metoclopramide, which blocks certain chemicals in the body to reduce nausea and vomiting.

The suppository is administered rectally, where it dissolves or melts to release the medication. The active ingredients are then absorbed into the bloodstream through the walls of the rectum. For optimal results, the suppository should be inserted into the rectum and left in place for at least 15 minutes before being removed.

When using Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository, it is crucial to adhere to the instructions provided by your healthcare provider or pharmacist. This medication should not be used for more than 5 consecutive days due to the risk of serious side effects. If you experience any adverse reactions, such as dizziness, drowsiness, or confusion, it is important to contact your healthcare provider or pharmacist immediately.

If you have any questions or concerns about Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository, or any other medication, please do not hesitate to reach out to us at Bayview Pharmacy. Our team is dedicated to providing you with the information you need to make informed decisions about your health and medications.

Other Uses

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Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is a compounded formulation that serves multiple therapeutic purposes. It is primarily used for the management of severe pain, but it also has other potential uses. This formulation can be used to treat abdominal pain, constipation, and diarrhea. It may also be beneficial in reducing the severity of opioid withdrawal symptoms, providing relief to those undergoing treatment for opioid addiction.

Another significant use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is in the prevention of aspiration in patients with impaired gastric emptying. This can be particularly useful in patients with certain gastrointestinal disorders or those undergoing specific medical procedures. Furthermore, it can be used to mitigate the risk of postoperative nausea and vomiting, a common side effect experienced by many patients after surgery.

Postoperative ileus, a condition characterized by a temporary loss of bowel function after surgery, can also be managed with this formulation. It may also be used to reduce the risk of postoperative pain, providing comfort and facilitating recovery. Additionally, it can be used to prevent postoperative urinary retention and constipation, further enhancing patient comfort and recovery.

Another potential use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository is in the prevention of postoperative respiratory depression, a serious complication that can occur after surgery. This formulation can help ensure the safety and well-being of patients during their postoperative period.

If you have any questions about the use of Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository for any of these conditions, please do not hesitate to reach out for more information.

Frequently Asked Questions

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What is the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository?

This is a compounded formulation of two medications, Morphine Sulfate and Metoclopramide, in a solid dosage form that is inserted into a body cavity, typically the rectum or vagina. It dissolves or melts to release the medication for local or systemic absorption.

How does the Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository work?

Once inserted into the body cavity, the suppository dissolves or melts, releasing the Morphine Sulfate and Metoclopramide. These medications are then absorbed into the body either locally or systemically, depending on the intended treatment.

What is this suppository used for?

The Morphine Sulfate/Metoclopramide suppository is typically used for pain management and to treat conditions like nausea and vomiting. However, the specific use may vary depending on the patient's condition and doctor's prescription.

How should I use this suppository?

This suppository should be used as directed by your healthcare provider. It is typically inserted into the rectum or vagina. Wash your hands before and after use, and try to hold the suppository in for as long as possible to allow the medication to be fully absorbed.

What are the potential side effects of this suppository?

Side effects can vary depending on the individual, but may include constipation, nausea, and dizziness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I use this suppository if I am pregnant or breastfeeding?

Always consult your healthcare provider before using any medication while pregnant or breastfeeding. They will be able to advise you on the potential risks and benefits.

Can I use this suppository with other medications?

Before using this suppository, inform your healthcare provider about any other medications you are currently taking. Some medications may interact with Morphine Sulfate and Metoclopramide, affecting their effectiveness or causing side effects.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use two doses at the same time or extra doses.

How should I store this suppository?

Store this suppository in a cool, dry place, away from direct heat and light. Keep it out of the reach of children and pets. Do not use it if the suppository appears damaged or if the packaging is torn.

What should I do in case of an overdose?

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include severe drowsiness, slow breathing, or loss of consciousness.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Morphine Sulfate 50 mg/Metoclopramide 10 mg Suppository
Suppository
30 suppositories
controlled

Insert 1 unwrapped suppository

Every 4 hours as needed