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The Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream is a semisolid preparation that combines the antifungal properties of Nystatin with the protective and soothing action of Zinc Oxide. This cream is specifically formulated to treat cutaneous fungal infections, such as diaper rash complicated by yeast infection (Candidiasis), and to provide a barrier to prevent further irritation and moisture accumulation. The inclusion of Zinc Oxide also helps in treating and preventing minor skin irritations and abrasions. The cream is dispensed in a pump mechanism, which allows for convenient, hygienic, and controlled application, ensuring that the affected area of the skin receives an accurate dose with minimal waste. This formulation is designed for topical use only and should be applied as directed by a healthcare professional.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream is a specially compounded medication designed to provide targeted relief and treatment for certain skin conditions. It works by binding to sterols in the fungal cell membrane, altering the permeability, and causing leakage of cell contents. This concentration of 3000 IU is intended to deliver a potent dose to the affected area, thereby reducing the fungal load and alleviating symptoms such as itching, redness, and discomfort.
Zinc oxide, on the other hand, is a skin protectant with mild astringent and antiseptic properties. At a concentration of 0.75%, it forms a protective barrier on the skin, which helps to soothe irritation and promote healing. It is particularly useful in treating diaper rash, minor burns, severely chapped skin, or other minor skin irritations. The combination of nystatin and zinc oxide in this cream provides a comprehensive treatment approach, addressing both the infection and the skin's protective barrier.
The cream is formulated as a semisolid preparation, which allows for a smooth and even application to the skin. The use of a pump mechanism for dispensing the cream ensures that the medication is delivered in a controlled manner, reducing waste and contamination, and enhancing the ease of use for patients. This is especially beneficial for those with limited dexterity or for caregivers administering the medication to others.
This formulation is indicated for the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species and for the protection and healing of irritated or chafed skin.
Patients and prescribers considering the use of Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream should be aware of the potential side effects, which may include skin irritation, burning, or rash. If any severe reactions or signs of allergic response occur, use of the medication should be discontinued, and medical advice should be sought. As with all medications, it is crucial to use this cream as directed by a healthcare professional and to adhere to the prescribed treatment regimen.
For further information, questions, or to discuss the suitability of this formulation for specific patients, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and is ready to assist with any inquiries regarding this or other compounded medications.
Nystatin is an antifungal medication that works by binding to sterols in the membranes of susceptible fungi, altering the permeability of the cell membrane and resulting in the leakage of cellular contents. It is commonly used to treat cutaneous or mucocutaneous mycotic infections caused by Candida species. Zinc oxide, on the other hand, is a skin protectant with mild astringent and antiseptic properties. It is often used to treat and prevent diaper rash and other minor skin irritations by forming a protective barrier on the skin to help seal out wetness.
When considering the drug interactions for a topical cream containing Nystatin and Zinc Oxide, it is important to note that systemic absorption of these agents is minimal. However, certain interactions may still be relevant. For instance, the concomitant use of other topical preparations on the same area of skin should be approached with caution. The presence of other products may alter the absorption or effectiveness of Nystatin and Zinc Oxide. Patients should be advised to allow adequate time between the application of different products.
While Nystatin is not known to interact significantly with systemic medications, it is always prudent to consider the potential for local interactions with other topical agents. For example, the use of occlusive dressings over the site of application can increase the absorption of topical drugs and may increase the risk of systemic side effects, although this is unlikely with Nystatin and Zinc Oxide. Additionally, the use of other topical antifungals or corticosteroids in the same area should be done under the guidance of a healthcare provider to avoid potential additive effects or alteration in efficacy.
Zinc oxide may interact with other topical preparations that contain irritants or other astringent compounds, potentially leading to increased irritation or drying of the skin. Patients should avoid using other topical products that contain these types of ingredients unless directed by a healthcare provider. Furthermore, the application of Zinc Oxide on deep or puncture wounds, animal bites, or serious burns should be avoided unless under medical supervision, as it may interfere with the healing process.
It is also important to consider the potential for allergic reactions or sensitivities to either Nystatin, Zinc Oxide, or any of the excipients in the formulation. Patients with known hypersensitivities should not use this product. If a patient experiences signs of an allergic reaction, such as rash, itching, or swelling, they should discontinue use and seek medical attention.
In summary, while the risk of systemic drug interactions with Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream is low, caution should be exercised when using other topical products concurrently. Patients should be advised to follow the prescribed directions for use and to consult with a healthcare provider before combining this medication with other topical therapies. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.
The Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream is a specially designed formulation that combines the antifungal properties of Nystatin with the protective and soothing effects of Zinc Oxide. This cream is intended for topical application on the skin, where it works by targeting specific disease states such as cutaneous candidiasis, diaper rash, and other minor skin irritations where a yeast infection may be present.
Nystatin is an antifungal antibiotic that binds to sterols in the cell membranes of susceptible fungi, particularly Candida species. This binding disrupts the cell membrane, causing leakage of cellular contents and ultimately the death of the fungal cell. With a concentration of 3000 IU per application, Nystatin in this cream is potent enough to effectively reduce the fungal load on the skin, alleviating symptoms such as itching, redness, and discomfort associated with yeast infections.
Zinc Oxide, on the other hand, serves a dual purpose. As a skin protectant, it forms a barrier on the skin's surface, shielding it from moisture, irritants, and other external factors that can exacerbate skin conditions. This barrier effect is particularly beneficial in the treatment of diaper rash, as it can help prevent further irritation from urine and feces. Additionally, Zinc Oxide has mild astringent properties, which means it can help to dry out weeping or oozing skin irritations, promoting a healthier skin environment for recovery.
The cream is formulated as a semisolid preparation, which allows for the active ingredients to be evenly distributed and easily absorbed by the skin. The pump mechanism of the container is designed to dispense a controlled amount of the cream with each use, ensuring consistent dosing and minimizing waste. This method of application is not only convenient but also helps to maintain the sterility of the product, reducing the risk of contamination that can occur with jar packaging.
For patients and prescribers considering the use of this formulation, it is important to note that the cream should be applied to the affected area as directed, usually several times a day, depending on the severity of the condition. The area should be clean and dry before application. It is also crucial to continue using the cream for the full course of treatment, even if symptoms begin to improve, to prevent the recurrence of infection.
If you have any questions about the Nystatin 3000 IU/Zinc Oxide 0.75% Topical Cream or its use in treating specific skin conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your health or the health of your patients.
This topical cream is used to treat skin conditions that may benefit from the antifungal properties of nystatin and the protective barrier provided by zinc oxide.
Apply a thin layer of the cream to the affected area as directed by your healthcare provider. It is usually applied several times a day; make sure to follow the specific instructions provided with your prescription.
Yes, the pump mechanism is designed to dispense a controlled amount of cream with each use, ensuring a consistent dose is applied each time. It also helps maintain the product's sterility and prevents contamination.
No, this cream is intended only for external use on the skin. Do not apply it to internal areas or mucous membranes. If you have an internal infection, consult your healthcare provider for appropriate treatment options.
While the Nystatin/Zinc Oxide Topical Cream can be used in pediatric patients, it is important to have a pediatrician's recommendation and supervision. Dosage and frequency can vary based on the child's age and medical condition.
Side effects may include skin irritation, rash, or an allergic reaction at the site of application. If you notice any severe side effects or signs of an allergic reaction (such as hives, difficulty breathing, or swelling), seek medical attention immediately.
You should consult with your healthcare provider before using this cream with other topical medications. There may be a risk of interactions, or one medication may alter the effectiveness of the other.
Store the cream at room temperature, away from direct sunlight and heat. Do not freeze the cream, and keep the container tightly closed when not in use. Also, keep it out of reach of children and pets.
If you miss a dose of the cream, apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and proceed with your regular dosing schedule. Do not double up on applications to make up for a missed dose.
No, avoid using the cream on open wounds or severely damaged skin, unless specifically directed by your healthcare provider. The product is meant for intact skin infections and irritations.
The time it takes for the cream to show improvement in symptoms can vary depending on the severity and type of skin condition being treated. Some individuals may notice improvement within a few days, while for others it may take longer. Follow your healthcare provider's guidance and complete the full course of treatment even if symptoms improve before the medication is finished.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
