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The Oxybuprocaine HCl 0.4%/Phenylephrine HCl 2.5%/Tropicamide 1% Ophthalmic Liquid is a compounded sterile preparation designed for ophthalmic use. Oxybuprocaine, a local anesthetic, provides rapid and short-term anesthesia to the ocular surface, making it useful for diagnostic procedures and minor surgical interventions. Phenylephrine HCl, a sympathomimetic agent, acts as a decongestant and mydriatic, dilating the pupil and facilitating intraocular examinations. Tropicamide, an anticholinergic, further enhances mydriasis and induces cycloplegia, temporarily paralyzing the ciliary muscle of the eye. This combination is commonly used to facilitate a comprehensive ophthalmic examination, including fundoscopy, and is also employed in diagnostic procedures that require pupil dilation or ocular anesthesia. Additionally, it may be used in preoperative settings to prepare the eye for surgery.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Oxybuprocaine HCl 0.4%/Phenylephrine HCl 2.5%/Tropicamide 1% Ophthalmic Liquid is a compounded medication specifically formulated for ophthalmic use. This unique combination of active ingredients serves multiple purposes in the management of ocular conditions. Oxybuprocaine, a local anesthetic, provides rapid and short-term numbing of the eye surface, making it useful for procedures that require the reduction of discomfort and reflex blinking. Phenylephrine HCl is a sympathomimetic agent that induces vasoconstriction, thereby reducing redness and swelling; it also serves as a mydriatic, dilating the pupil for better examination of the interior structures of the eye. Tropicamide, an anticholinergic, further facilitates pupil dilation (mydriasis) and temporarily paralyzes the ciliary muscle (cycloplegia), aiding in diagnostic procedures and in the treatment of inflammatory conditions that benefit from reduced lens movement.
This combination is particularly useful in diagnostic procedures such as fundoscopy, where a clear view of the retina is required, and for pre-operative preparation in cataract surgery. It can also be used in the treatment of anterior uveitis, where pupil dilation helps prevent the formation of synechiae and reduces pain associated with ciliary spasm. The formulation is designed for topical ophthalmic use and should be administered as per the prescribing physician's instructions, taking care to avoid contamination of the dropper tip and bottle.
Patients should be counseled on the potential side effects, which may include transient stinging upon instillation, increased light sensitivity, and a temporary blurring of vision. Systemic absorption, although minimal, can lead to side effects such as increased heart rate or blood pressure, particularly with phenylephrine. Therefore, caution is advised in patients with cardiovascular conditions. It is also important to note that the effects of pupil dilation can last for several hours, during which time patients should not drive or operate heavy machinery.
Prescribers should consider the patient's overall medical condition before using this formulation, as certain systemic diseases may contraindicate its use. Additionally, the potential for drug interactions, particularly with other mydriatics or medications affecting the cardiovascular system, should be evaluated. As with all compounded medications, this formulation should be used under the guidance of a healthcare professional familiar with the patient's medical history and current medication regimen.
Bayview Pharmacy is committed to providing high-quality, customized medications to meet the specific needs of patients and healthcare providers. Our team of compounding pharmacists is available to answer any questions and provide additional information about this ophthalmic liquid formulation. If you have any questions or require further assistance, please do not hesitate to reach out to us.
The formulation of Oxybuprocaine HCl 0.4%/Phenylephrine HCl 2.5%/Tropicamide 1% Ophthalmic Liquid is a combination of an anesthetic, a sympathomimetic, and an anticholinergic agent, respectively, used primarily in ophthalmic procedures to facilitate examination and procedures by providing local anesthesia, pupil dilation, and vasoconstriction. Oxybuprocaine is a local anesthetic that temporarily numbs the surface of the eye, Phenylephrine is a decongestant that dilates the pupil and reduces redness by constricting blood vessels, and Tropicamide is a muscarinic antagonist that causes muscles in the eye to relax, resulting in pupil dilation.
When considering drug interactions, it is important to note that although the systemic absorption of ophthalmic solutions is typically low, there is still potential for systemic effects and interactions, particularly in patients with compromised corneal barriers or those receiving the drops over a prolonged period. Oxybuprocaine may interact with other local anesthetics, and caution should be exercised if the patient is using other topical anesthetics concurrently. Phenylephrine may interact with monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and other sympathomimetics, potentially leading to an increase in blood pressure. Caution is advised when using this medication in patients taking antihypertensive drugs, as there may be a reduced efficacy of the antihypertensive treatment. Tropicamide may interact with other anticholinergic drugs, potentially increasing the risk of anticholinergic side effects such as dry mouth, blurred vision, and increased intraocular pressure. Additionally, the use of tropicamide in patients taking drugs that can cause CNS depression (such as benzodiazepines, opiates, and barbiturates) may result in additive effects.
Patients with pre-existing conditions such as glaucoma, hypertension, cardiac disease, or hyperthyroidism should be monitored closely due to the potential for exacerbation of these conditions. It is also important to consider the potential for additive systemic effects when this ophthalmic solution is used in conjunction with other systemic medications that can affect blood pressure, heart rate, or intraocular pressure.
For prescribers, it is crucial to review the patient's current medication list for potential interactions before prescribing this ophthalmic solution. Adjustments to therapy or additional monitoring may be necessary to ensure patient safety. Patients should be advised to inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.
If you have any questions or require further information regarding drug interactions with this ophthalmic formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support to ensure the safe and appropriate use of this medication.
The formulation of Oxybuprocaine HCl 0.4%/Phenylephrine HCl 2.5%/Tropicamide 1% Ophthalmic Solution is a compounded medication designed for use in ophthalmic procedures. This combination of active ingredients works synergistically to provide both diagnostic and therapeutic benefits for certain eye conditions. Each component plays a specific role in the treatment process.
Oxybuprocaine HCl, also known as benoxinate, is a local anesthetic used in ophthalmology. It works by blocking the sodium channels in the neuronal membrane, which inhibits the initiation and conduction of nerve impulses. This results in a temporary loss of sensation in the eye, providing pain relief and comfort during diagnostic procedures or minor surgical interventions.
Phenylephrine HCl is a sympathomimetic agent that acts as a selective alpha-1 adrenergic receptor agonist. When applied topically to the eye, it causes vasoconstriction of the conjunctival blood vessels, leading to decreased redness and swelling. Additionally, phenylephrine is used to dilate the pupil (mydriasis) without affecting the ability to focus (cycloplegia).
Tropicamide is a muscarinic receptor antagonist that induces both mydriasis and cycloplegia by inhibiting the action of acetylcholine within the muscles of the iris and ciliary body. The 1% concentration of tropicamide in this formulation provides rapid and short-acting dilation of the pupil, which is useful for diagnostic purposes such as fundoscopic examination and for pre-surgical preparation.
This combination ophthalmic solution is particularly useful in diagnosing and treating conditions that require a detailed examination of the interior structures of the eye, such as uveitis, glaucoma, and retinal detachment. It is also used in preoperative settings to prepare the eye for surgery by providing adequate mydriasis and anesthesia. The compounded solution ensures that the effects of the individual components are delivered simultaneously, improving patient comfort and procedural efficiency.
It is important for both patients and prescribers to understand the pharmacological actions, potential side effects, and contraindications associated with each component of this formulation. Patients should be monitored for systemic absorption, especially with phenylephrine, which can cause cardiovascular effects in sensitive individuals. As with any ophthalmic solution, sterility is paramount to prevent ocular infections.
If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing you with the necessary support and guidance to ensure the safe and appropriate use of this ophthalmic solution.
This compounded ophthalmic solution is typically used for diagnostic purposes during an eye examination. Oxybuprocaine HCl is an anesthetic used to numb the eye, Phenylephrine HCl is a decongestant that dilates the pupil and improves the doctor's view of the inner eye, and Tropicamide is a mydriatic that also dilates the pupil for better examination and diagnosis.
You should use this medication only as directed by your healthcare provider. Generally, one or two drops are instilled into the affected eye or eyes shortly before the eye examination. Your healthcare provider will give you specific instructions based on your condition and response to treatment.
Yes, as with any medication, there can be side effects. Common side effects include temporary stinging or burning of the eyes immediately after instillation, increased sensitivity to light, and blurred vision. If you experience severe or persistent side effects, you should contact your healthcare provider.
It is generally not recommended to drive immediately after using this medication due to its effects such as pupil dilation and blurred vision. These effects can impair your ability to drive safely. It is important to wait until your vision returns to normal before driving or operating heavy machinery.
This compounded ophthalmic liquid can be used in children as directed by a healthcare provider. However, the dosage may differ from that used in adults, and the child's response to the drug will be closely monitored.
The effects of the medication can vary from person to person, but typically, the pupil dilation (from the Phenylephrine HCl and Tropicamide) can last for several hours, and the numbing effect of Oxybuprocaine HCl typically wears off within a half-hour. Make sure to discuss the duration of effects with your healthcare provider.
If you experience severe discomfort, swelling, redness, or signs of an allergic reaction, such as hives or difficulty breathing, seek immediate medical attention.
No, you should remove your contact lenses before instilling the drops. The chemicals can accumulate on the contact lenses and may cause irritation. Plus, some components of the solution can temporarily change the fit of your contacts. Contacts can be reinserted after a period of time as advised by your healthcare provider.
If you are using other eye medications, you should consult with your healthcare provider for specific instructions. Generally, if you are using more than one type of eye medication, you should wait at least 5 to 10 minutes before instilling the next medication to allow proper absorption.
The compounded solution should be stored at room temperature away from light and moisture. Do not freeze the medication, and keep it out of reach of children and pets. Consult with your healthcare provider or pharmacist for specific storage instructions.
This medication is specifically formulated for diagnostic purposes during eye examinations and should not be used to treat other eye conditions unless specifically directed by your healthcare provider. Using the medication without professional guidance can potentially harm your eyes.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
