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Papaverine HCl 0.1%/Arginine 6% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Papaverine Hydrochloride

Papaverine HCl 0.1%/Arginine 6% Topical Cream is a specially compounded semisolid preparation, dispensed via a pump mechanism for easy and controlled application. It is designed for localized treatment on the skin, facilitating the absorption of active ingredients. This medication is used to manage conditions such as erectile dysfunction, Peyronie's disease, priapism, Raynaud's syndrome, and vascular insufficiency.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Papaverine Hydrochloride
Topical Cream
6427079ea643243f05518fb0

Formula Information

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This compounded formulation of Papaverine HCl 0.1% and Arginine 6% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is specifically formulated for localized treatment or absorption of active ingredients. This topical cream is used to treat a variety of conditions, including Erectile Dysfunction, Peyronie's Disease, Priapism, Raynaud's Syndrome, and Hyperhidrosis.

Papaverine HCl is a vasodilator that works by relaxing the smooth muscles of the penis, thereby allowing for increased blood flow and improved erectile function. On the other hand, Arginine is an amino acid that aids in increasing nitric oxide production, which helps to improve blood flow and reduce inflammation. The synergistic action of these two ingredients helps to improve erectile function and alleviate symptoms associated with the aforementioned conditions.

The cream is easy to use and can be applied directly to the affected area. It is crucial to adhere to the instructions provided by your healthcare provider when using this product. It is also important to note that this product should not be used in combination with other medications or supplements without consulting your healthcare provider, as this could lead to adverse reactions.

If you have any questions about this formulation or how it can help treat your condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with your healthcare needs. Please note that while we strive to provide the most accurate and up-to-date information, we encourage you to consult with your healthcare provider for personalized medical advice.

Drug Interactions

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This compounded formulation of Papaverine HCl 0.1%/Arginine 6% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is specifically formulated for localized treatment or absorption of active ingredients. The cream is indicated for the treatment of various conditions including Erectile Dysfunction, Peyronie's Disease, Priapism, Raynaud's Syndrome, and Hyperhidrosis.

Papaverine HCl, a key ingredient in this formulation, is a smooth muscle relaxant that plays a crucial role in relaxing the muscles of the penis. This action facilitates increased blood flow and improved erectile function. Arginine, on the other hand, is an amino acid that aids in the increase of nitric oxide production. This process helps to relax the blood vessels and improve blood flow.

The combination of these ingredients in this topical cream formulation works synergistically to improve erectile function, reduce pain associated with Peyronie's Disease, and decrease the duration of Priapism episodes. Additionally, it may help to alleviate the symptoms of Raynaud's Syndrome, such as coldness and numbness in the extremities. The cream may also be beneficial in reducing excessive sweating associated with Hyperhidrosis.

If you have any questions about this formulation or its application, please do not hesitate to reach out for further information.

How Does it Work

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This compounded formulation of Papaverine HCl 0.1%/Arginine 6% Topical Cream is a semisolid preparation designed for convenient and controlled application on the skin. It is dispensed in a pump mechanism, ensuring precise dosage and ease of use. The cream is intended for localized treatment, allowing for the absorption of active ingredients directly into the affected area.

The cream combines the vasodilating properties of Papaverine HCl and the nitric oxide boosting effects of Arginine. Papaverine HCl is a potent vasodilator that relaxes the smooth muscles of the blood vessels, promoting increased blood flow. Arginine, an essential amino acid, aids in the production of nitric oxide, a compound that further relaxes blood vessels. Together, these ingredients work synergistically to enhance blood flow to the targeted area.

For Erectile Dysfunction, the cream can be applied directly to the penis, where it works by increasing blood flow to improve erectile function. In the case of Peyronie's Disease, the cream can be applied to the affected area to help reduce penile curvature. For Priapism, the cream can help reduce the duration and severity of the condition when applied to the affected area. For Raynaud's Syndrome, the cream can help reduce the frequency and severity of the condition when applied to the affected area. For Hyperhidrosis, the cream can be applied to the affected area to help reduce excessive sweating.

It is crucial to note that this topical cream should not be used in conjunction with other medications or treatments for the aforementioned conditions without consulting a healthcare professional. If you have any questions or concerns about using this formulation, please consult your healthcare provider.

Other Uses

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This compounded formulation of Papaverine HCl 0.1%/Arginine 6% Topical Cream is a versatile treatment option with a wide range of potential applications. It may be used to treat conditions such as chronic venous insufficiency, varicose veins, and thrombophlebitis, helping to improve blood flow and reduce inflammation in these areas. The cream may also be beneficial for those experiencing muscle spasms, cramps, and spasticity, providing relief from pain and discomfort. Furthermore, it may be used to reduce the risk of thrombosis and improve circulation in the extremities, potentially reducing the risk of stroke and heart attack. This formulation may also be beneficial in reducing the risk of developing deep vein thrombosis. If you have any questions about the use of this formulation, please do not hesitate to reach out for further information.

Frequently Asked Questions

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What is Papaverine HCl 0.1%/Arginine 6% Topical Cream?

This is a compounded formulation of two active ingredients, Papaverine HCl and Arginine, designed to be applied topically on the skin. It is dispensed in a pump mechanism for convenient and controlled application.

What is the purpose of the pump mechanism?

The pump mechanism is designed to provide a convenient and controlled application of the cream. It ensures that the right amount of cream is dispensed each time, reducing the risk of overuse or underuse.

How does Papaverine HCl 0.1%/Arginine 6% Topical Cream work?

The cream works by delivering the active ingredients, Papaverine HCl and Arginine, directly to the area of the skin where they are needed. This allows for localized treatment and absorption.

What are the active ingredients in this cream?

The active ingredients in this cream are Papaverine HCl at a concentration of 0.1% and Arginine at a concentration of 6%.

How should I store this cream?

Store this cream at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children.

How often should I apply this cream?

The frequency of application will depend on your specific condition and the instructions provided by your healthcare provider. Always follow the directions given to you by your healthcare provider.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Can I use this cream on broken or irritated skin?

No, this cream should not be used on broken or irritated skin unless directed by your healthcare provider. It is designed for application on healthy skin for localized treatment.

What should I do if I experience any side effects?

If you experience any side effects, such as skin irritation or allergic reactions, stop using the cream and contact your healthcare provider immediately.

Can I use this cream if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should consult your healthcare provider before using this cream. The effects of the active ingredients on unborn babies or nursing infants are not fully known.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Papaverine HCl 0.1%/Arginine 6% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)

Apply topically to affected area(s) 2-3 times daily.