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Pergolide Mesylate 0.2 mg/ml Oral Liquid is a specially compounded medication designed for oral use, offering a precise and manageable method of drug delivery. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing pills, such as those in pediatric and geriatric groups. The medication is used in the treatment of Parkinson's disease, a neurodegenerative disorder characterized by motor symptoms such as tremors, stiffness, and bradykinesia. It may also be prescribed for other conditions as determined by a healthcare provider.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Pergolide Mesylate 0.2 mg/ml Oral Liquid is a specially compounded medication designed for oral use, providing a precise 0.2 mg of pergolide mesylate per milliliter of liquid. This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as those in pediatric or geriatric populations, or for individuals with conditions that impair their ability to ingest solid dosage forms. The liquid form allows for flexible dosing, which can be easily adjusted according to the specific needs of the patient.
Pergolide mesylate is a dopamine agonist that mimics the action of dopamine in the brain. It is primarily used in the treatment of Parkinson's disease, a neurodegenerative disorder characterized by tremors, stiffness, and bradykinesia (slowness of movement). By stimulating dopamine receptors, pergolide helps to alleviate the motor symptoms associated with the disease, improving the quality of life for those affected. Additionally, pergolide mesylate has been used off-label for the treatment of hyperprolactinemia, a condition where there is an excess of prolactin in the blood, often leading to various symptoms including infertility and bone loss.
It is important for both patients and prescribers to be aware that pergolide mesylate can have side effects, including nausea, dizziness, and orthostatic hypotension, among others. Regular monitoring and dose adjustments may be necessary to minimize these effects. Furthermore, due to the potential for serious heart valve damage, the use of pergolide mesylate should be carefully considered and regularly evaluated by a healthcare professional. Patients should be counseled on the importance of adhering to their prescribed dosing schedule and to report any adverse effects or concerns to their healthcare provider promptly.
At Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the unique needs of our patients. Our team of expert compounding pharmacists is available to answer any questions and provide guidance on the use of Pergolide Mesylate 0.2 mg/ml Oral Liquid. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us.
Pergolide mesylate is a dopamine agonist that is used primarily to treat Parkinson's disease by mimicking the action of dopamine in the brain, which is typically low in individuals with this condition. It can also be used for other conditions as determined by a healthcare provider. When considering the use of pergolide mesylate 0.2 mg/ml oral liquid, it is important to be aware of potential drug interactions that could affect the efficacy of the medication or increase the risk of adverse effects.
One significant interaction is with anti-psychotic medications, such as phenothiazines, butyrophenones, thioxanthenes, or metoclopramide, which can diminish the effectiveness of pergolide by blocking dopamine receptors. Patients taking these medications should consult their healthcare provider before starting pergolide. Additionally, caution is advised when pergolide is co-administered with other central nervous system (CNS) depressants, including alcohol, benzodiazepines, and opioids, as these can exacerbate CNS depression and lead to increased drowsiness or dizziness.
Medications that inhibit CYP3A4, an enzyme responsible for the metabolism of pergolide, such as erythromycin, clarithromycin, and azole antifungals (e.g., ketoconazole, itraconazole), can increase pergolide levels in the blood and may necessitate dosage adjustments. Conversely, CYP3A4 inducers like rifampin, carbamazepine, and phenytoin can decrease pergolide levels and reduce its effectiveness. Blood pressure-lowering medications may have their effects potentiated by pergolide, leading to an increased risk of hypotension, so careful monitoring of blood pressure is recommended when these drugs are used concurrently.
Patients should also be aware that pergolide can interact with other dopamine agonists or antagonists, as these can either enhance or counteract the therapeutic effects of pergolide. Additionally, since pergolide can cause drowsiness, patients should be cautious when taking other medications that can cause sedation, such as antihistamines or sleep medications.
It is crucial for patients to inform their healthcare provider of all medications, supplements, and over-the-counter drugs they are currently taking before starting treatment with pergolide mesylate oral liquid. This will help to identify any potential interactions and allow for proper management. If you have any questions or concerns about drug interactions with pergolide mesylate, please reach out to us at Bayview Pharmacy for further assistance.
Pergolide mesylate is a dopamine agonist that mimics the action of dopamine in the brain. Pergolide mesylate works by stimulating dopamine receptors in the brain, which helps to improve these symptoms. The efficacy of pergolide in treating Parkinson's disease has been well-documented, and it has been a valuable therapeutic option for patients who may not respond adequately to other treatments.
The 0.2 mg/ml oral liquid formulation of pergolide mesylate provides a precise dosage that can be easily adjusted to meet the individual needs of patients. This is particularly beneficial for those who require a tailored approach to their medication regimen, such as patients with fluctuating symptoms or those who experience side effects at higher doses. The liquid form is also advantageous for patients who have difficulty swallowing pills, such as the elderly or those with dysphagia. Additionally, the oral liquid can be more palatable and easier to administer to pediatric patients who may be resistant to taking solid dosage forms.
When administered, the pergolide mesylate oral liquid is absorbed through the gastrointestinal tract and enters the bloodstream, where it is transported to the brain. Once in the brain, it crosses the blood-brain barrier and binds to dopamine receptors, particularly D2 receptors, which are involved in motor control. By activating these receptors, pergolide mesylate helps to restore the balance of dopamine and improve motor function in patients with Parkinson's disease. It may also be used in the treatment of other conditions where dopamine agonist therapy is indicated, such as restless legs syndrome or pituitary gland tumors producing prolactin.
It is important for patients and prescribers to understand that while pergolide mesylate can significantly improve symptoms, it does not cure Parkinson's disease or other related disorders. Long-term management and regular monitoring by a healthcare professional are essential to optimize treatment outcomes and manage any potential side effects. Patients should also be aware that abrupt discontinuation of the medication can lead to withdrawal symptoms and a rapid return of disease symptoms, so any changes to the medication regimen should be made under the guidance of a healthcare provider.
For more detailed information on the use of pergolide mesylate 0.2 mg/ml oral liquid, or if you have any questions regarding this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to both patients and prescribers to ensure the safe and appropriate use of this medication.
Pergolide Mesylate Oral Liquid is prescribed to treat symptoms of Parkinson's disease. It helps to improve symptoms such as shakiness, stiffness, and difficulty moving by mimicking the effects of dopamine in the brain.
This medication should be taken exactly as prescribed by your doctor. The liquid formulation is typically administered using a special measuring device for accurate dosing, and can be taken with or without food. Do not use a household spoon because you may not get the correct dose.
Yes, Pergolide Mesylate Oral Liquid can be taken with or without food, according to your preference or doctor's instructions. Sometimes taking it with food can help to reduce nausea, which is a potential side effect of the medication.
The liquid should be stored at room temperature, away from direct light and moisture. Do not store it in the bathroom, and keep all medications away from children and pets.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Yes, as with any medication, there are potential side effects which may include nausea, vomiting, drowsiness, dizziness, lightheadedness, or constipation. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
It is important to follow your doctor's instructions on how to take this medication. Some liquid medications can be mixed with certain foods or liquids to make them easier to take, but always ask your healthcare provider before altering how you take your medication.
The suitability for children will depend on the specific case and the doctor's judgment. Always follow the pediatrician's or neurologist's guidance regarding dosing and administration to pediatric patients.
Pergolide Mesylate Oral Liquid may cause dizziness or drowsiness, potentially affecting your ability to drive or operate machinery. Do not drive or perform tasks that require alertness until you are sure you can do so safely.
You should avoid alcohol, as it can increase certain side effects such as dizziness and drowsiness. Discuss with your doctor any activities or substances you should steer clear of while taking this medication.
An overdose of any medication is dangerous. If you or someone else has taken too much Pergolide Mesylate Oral Liquid and is experiencing serious symptoms such as passing out or trouble breathing, call emergency medical services or a poison control center immediately.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
