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Phenytoin 2% Lidocaine 6% Topical Powder

Phenytoin 2% Lidocaine 6% Topical Powder is a compounded treatment from Bayview Pharmacy, designed to help manage nerve pain, diabetic neuropathy, and postherpetic neuralgia.
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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Phenytoin
Lidocaine Hydrochloride
Topical Powder
66fd7b0bdc31c32733aec9f2

Formula Information

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Phenytoin 2% Lidocaine 6% Topical Powder is a compounded formulation designed for external application to the skin, combining the wound-healing properties of phenytoin with the analgesic effects of lidocaine.

Phenytoin, at a concentration of 2%, has been shown to promote wound healing by stimulating fibroblast proliferation, enhancing collagen deposition, and reducing inflammation. This makes it beneficial

Drug Interactions

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Phenytoin 2% Lidocaine 6% Topical Powder is a compounded formulation designed for external application to the skin. It is often used for its soothing properties, moisture absorption, and ability to reduce friction, making it suitable for various dermatological conditions. Phenytoin, an anticonvulsant, is known for its wound-healing properties, while lidocaine is a local anesthetic that provides pain relief. When combined in a topical powder form, they offer a unique therapeutic approach for managing skin conditions that may involve pain, irritation, or the need for enhanced healing.

While topical formulations generally have a lower risk of systemic drug interactions compared to oral medications, it is important to consider potential interactions, especially in patients who may be using other medications or have underlying health conditions. Phenytoin, when absorbed systemically, is known to interact with a wide range of drugs, including those that are metabolized by the cytochrome P450 enzyme system. Although systemic absorption from a topical application is minimal, caution is advised when using this formulation in patients who are on medications such as warfarin, oral contraceptives, or other anticonvulsants, as phenytoin can induce hepatic enzymes and potentially alter the metabolism of these drugs.

Lidocaine, when used topically, is generally well-tolerated and has a low risk of systemic interactions. However, in rare cases where significant absorption occurs, it may interact with antiarrhythmic drugs or other local anesthetics, potentially leading to additive effects on cardiac conduction. Patients with pre-existing cardiac conditions or those taking medications that affect cardiac function should use this formulation with caution and under medical supervision.

For patients and prescribers considering the use of Phenytoin 2% Lidocaine 6% Topical Powder, it is crucial to evaluate the patient's current medication regimen and medical history to identify any potential risks. Monitoring for signs of systemic absorption, such as unusual side effects or changes in the efficacy of other medications, is recommended. If any concerns or questions arise regarding the use of this formulation, please reach out to us for further guidance and support.

How Does it Work

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The Phenytoin 2% Lidocaine 6% Topical Powder is a specialized formulation designed to provide targeted relief and therapeutic benefits for various dermatological conditions. This finely divided dry formulation is intended for external application to the skin and is often packaged in a container with a dispensing mechanism for ease of use. The powder form offers several advantages, including moisture absorption, soothing properties, and the ability to reduce friction, making it an ideal choice for managing skin conditions that require these specific benefits.

Phenytoin, a well-known anticonvulsant, is utilized in this formulation for its wound-healing properties. When applied topically, phenytoin promotes the proliferation of fibroblasts and enhances collagen deposition, which are critical processes in wound healing. This action helps in the repair and regeneration of damaged skin tissues, making it beneficial for conditions that involve skin breakdown or ulceration. Additionally, phenytoin has anti-inflammatory properties that can help reduce local inflammation, further aiding in the healing process.

Lidocaine, a local anesthetic, is included in the formulation to provide immediate pain relief. By blocking sodium channels, lidocaine prevents the initiation and conduction of nerve impulses, effectively numbing the area of application. This action is particularly useful in conditions where pain is a significant symptom, offering patients relief and improving their quality of life. The 6% concentration of lidocaine ensures a potent and rapid onset of action.

The combination of phenytoin and lidocaine in a topical powder form allows for a synergistic effect, where the wound-healing properties of phenytoin complement the analgesic effects of lidocaine. This dual-action approach not only addresses the underlying skin condition but also provides symptomatic relief, making it a comprehensive treatment option. The powder form is especially beneficial for areas prone to moisture accumulation, as it helps keep the skin dry and reduces the risk of further irritation or infection.

For prescribers, this formulation offers a versatile treatment option that can be tailored to the specific needs of patients with dermatological conditions requiring both healing and pain management. It is important to consider the individual patient's condition and response to treatment when prescribing this formulation. Patients should be advised on the proper application technique to maximize the benefits of the powder and to ensure even distribution over the affected area.

If you have any questions or need further information about the Phenytoin 2% Lidocaine 6% Topical Powder, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation or its use in treating specific dermatological conditions.

Other Uses

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Phenytoin 2% Lidocaine 6% Topical Powder is a unique formulation that combines the anticonvulsant properties of phenytoin with the local anesthetic effects of lidocaine, designed for external application to the skin. While primarily used for dermatological conditions, this formulation has potential applications beyond its conventional uses. The powder form offers benefits such as moisture absorption, soothing properties, and friction reduction, making it suitable for a variety of skin-related issues. For patients experiencing discomfort from minor skin irritations, such as those caused by friction or moisture, this formulation can provide relief by creating a protective barrier and reducing irritation. Additionally, the anesthetic properties of lidocaine can help alleviate pain associated with superficial skin injuries, such as minor cuts, abrasions, or insect bites, offering a numbing effect that can enhance comfort during the healing process.

For prescribers, the combination of phenytoin and lidocaine in a topical powder form presents an innovative approach to managing conditions that involve both pain and inflammation. Phenytoin, known for its anti-inflammatory properties, can aid in reducing localized inflammation, while lidocaine provides immediate pain relief. This dual-action can be particularly beneficial in managing conditions like neuropathic pain or localized pain syndromes where both inflammation and pain are present. Furthermore, the powder form allows for easy application and can be particularly advantageous in areas where creams or ointments may not be suitable, such as in intertriginous zones or areas prone to moisture accumulation.

In addition to its dermatological applications, this formulation may also be considered for use in palliative care settings, where managing pain and skin integrity is crucial. The ease of application and the dual-action of pain relief and anti-inflammatory effects can contribute to improved patient comfort and quality of life. As with any compounded medication, it is essential for both patients and prescribers to discuss the specific needs and potential benefits of this formulation, considering individual patient circumstances and treatment goals. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or support you may need.

Frequently Asked Questions

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What is Phenytoin 2% Lidocaine 6% Topical Powder used for?

This topical powder is used for external application to the skin to help manage dermatological conditions. It offers benefits such as moisture absorption, soothing properties, and reducing friction, making it suitable for skincare routines.

How should I apply Phenytoin 2% Lidocaine 6% Topical Powder?

Apply the powder to clean, dry skin. Use the dispensing mechanism to evenly distribute a thin layer over the affected area. Avoid inhaling the powder during application.

Can I use this powder on open wounds?

No, this powder is intended for use on intact skin only. Avoid applying it to open wounds, broken skin, or mucous membranes.

How often can I use Phenytoin 2% Lidocaine 6% Topical Powder?

Follow your healthcare provider's instructions regarding frequency of use. Typically, it can be applied as needed, but do not exceed the recommended usage.

Are there any side effects associated with this topical powder?

Some users may experience mild skin irritation or allergic reactions. If you notice any severe reactions or persistent irritation, discontinue use and consult a healthcare professional.

Is this powder safe for children?

Consult a healthcare provider before using this product on children. They can provide guidance based on the child's specific condition and needs.

Can I use this powder with other topical medications?

Before combining this powder with other topical treatments, consult your healthcare provider to ensure there are no interactions or contraindications.

How should I store Phenytoin 2% Lidocaine 6% Topical Powder?

Store the powder in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I accidentally inhale the powder?

If you accidentally inhale the powder, move to an area with fresh air. If you experience any respiratory discomfort, seek medical attention promptly.

Can I use this powder during pregnancy or while breastfeeding?

Consult your healthcare provider before using this product if you are pregnant or breastfeeding to ensure it is safe for you and your baby.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Related Formulas

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Phenytoin 2% Lidocaine 6% Topical Powder
Topical Powder
238 g
controlled

Apply topically to affected area(s)