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Sodium Citrate 8.8% Oral Liquid

Sodium Citrate 8.8% Oral Liquid is a specially compounded medication designed for oral use, offering a precise and palatable dosage form for patients who may have difficulty swallowing pills or tablets. This aqueous solution is particularly suitable for pediatric and geriatric patients, ensuring ease of administration and accurate dosing. Sodium Citrate Oral Liquid is commonly used in the treatment of conditions that require urinary alkalinization, such as kidney stones (specifically uric acid stones) and certain metabolic acidosis states. It is also employed to relieve discomfort in urinary tract infections by reducing the acidity of urine.

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Oral Liquid
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Formula Information

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Sodium Citrate 8.8% Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This aqueous solution is particularly beneficial for patients who have difficulty swallowing pills, such as young children or elderly individuals. The active ingredient, sodium citrate, works by adjusting the acid-base balance in the body, making it an effective treatment for conditions that require urinary alkalinization. It is often prescribed for the management of certain kidney conditions, including the prevention of kidney stones (renal calculi) that may form in acidic urine. Additionally, sodium citrate is used to treat metabolic acidosis, a condition where there is too much acid in the body fluids, and can be used as a systemic and urinary alkalinizer.

The 8.8% concentration provides a reliable dosage strength, ensuring that patients receive a consistent amount of the active ingredient with each administration. The oral liquid form allows for flexible dosing, which can be adjusted according to the specific needs of the patient, as determined by the prescriber. This is particularly important in pediatric and geriatric populations, where dosing requirements may vary significantly. The liquid formulation also allows for rapid absorption and onset of action, which can be critical in acute treatment scenarios.

For prescribers considering Sodium Citrate 8.8% Oral Liquid, it is important to note that the medication should be used with caution in patients with renal impairment, heart disease, or those on a sodium-restricted diet, due to its sodium content. Monitoring of serum electrolytes and renal function may be necessary during prolonged use. As with all medications, potential interactions with other drugs should be considered, and the patient's complete medical history should be taken into account when prescribing this formulation.

Patients are advised to follow the dosing instructions provided by their healthcare provider and to report any unusual symptoms or side effects. It is also important for patients to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to avoid potential interactions. For optimal results, this medication should be taken as directed and stored at room temperature, away from light and moisture.

If you have any questions or require further information about Sodium Citrate 8.8% Oral Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of expert compounding pharmacists is dedicated to providing the highest quality of care and is available to assist with any inquiries regarding this formulation.

Drug Interactions

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Sodium citrate is an alkalinizing agent that works by neutralizing excess acid in the blood and urine. It is commonly used to treat conditions such as kidney stones, metabolic acidosis, and certain types of poisoning. When considering the use of sodium citrate 8.8% oral liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or lead to adverse effects.

One of the primary concerns with sodium citrate is its interaction with aluminum-containing antacids. When taken concurrently, sodium citrate can increase the absorption of aluminum, potentially leading to aluminum toxicity, especially in patients with impaired renal function. Therefore, it is advisable to separate the administration of sodium citrate and aluminum-containing antacids by at least two hours.

Additionally, sodium citrate can alter the excretion of certain medications by changing urinary pH. Drugs that are weak acids, such as salicylates, barbiturates, and lithium, may have decreased efficacy due to increased urinary excretion in the alkaline environment created by sodium citrate. Conversely, the excretion of weak bases, such as amphetamines and quinidine, may be reduced, leading to higher serum levels and potential toxicity. Careful monitoring and possible dose adjustments may be necessary when these drugs are used concomitantly with sodium citrate.

Patients on potassium-sparing diuretics or angiotensin-converting enzyme (ACE) inhibitors should use sodium citrate with caution, as it may lead to hyperkalemia. The risk is further increased in patients with renal impairment or those on a potassium-rich diet. Regular monitoring of serum potassium levels is recommended in these cases.

For patients on anticoagulant therapy, such as warfarin, the use of sodium citrate may necessitate additional monitoring of prothrombin time or international normalized ratio (INR), as changes in vitamin K absorption may occur due to alterations in intestinal pH.

It is also important to note that sodium citrate can affect the absorption of certain drugs by chelation or by altering gastric pH. Medications such as tetracyclines, fluoroquinolones, and levothyroxine may have reduced absorption when taken with sodium citrate, potentially leading to subtherapeutic effects. To minimize this interaction, it is recommended to administer these medications at least 2 hours before or 4-6 hours after taking sodium citrate.

Lastly, due to its sodium content, sodium citrate should be used with caution in patients with conditions that require sodium restriction, such as heart failure, hypertension, and edema. In such cases, monitoring of blood pressure and fluid balance is advised.

As with any medication, it is crucial to inform healthcare providers of all prescription, over-the-counter medications, and dietary supplements being taken to avoid potential drug interactions. If you have any questions or concerns regarding the use of sodium citrate 8.8% oral liquid, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Sodium Citrate 8.8% Oral Liquid is a specially designed medication that works by adjusting the acid-base balance in the body. Sodium citrate is a salt of citric acid, which has alkalizing properties. When ingested, it is metabolized to bicarbonate, which can then help to neutralize excess stomach acid. This can provide relief from conditions that are caused by too much acid in the bloodstream or urine, such as metabolic acidosis, certain kidney stones, and some types of poisoning.

In the treatment of metabolic acidosis, Sodium Citrate 8.8% Oral Liquid works by increasing the plasma bicarbonate, buffering excess hydrogen ion concentration, and raising blood pH, thereby reversing the clinical manifestations of acidosis. For patients with kidney stones, the alkalizing effect of sodium citrate helps to increase urinary pH and reduce the formation of new stones, particularly uric acid and cystine stones, which are more likely to form in acidic environments.

Additionally, Sodium Citrate 8.8% Oral Liquid can be used as a systemic and urinary alkalinizer in the management of certain intoxications, such as salicylate or phenobarbital overdose. By increasing the urinary pH, sodium citrate promotes the renal excretion of acidic drugs, which are more soluble in alkaline conditions, thus speeding up their elimination from the body.

The oral liquid formulation is particularly beneficial for patients who have difficulty swallowing pills, such as young children, the elderly, or those with esophageal disorders. The liquid form allows for flexible dosing and ensures that the medication can be administered accurately and safely. It is important to follow the prescribed dosage and administration instructions to achieve the desired therapeutic effect.

For patients and prescribers considering the use of Sodium Citrate 8.8% Oral Liquid, it is essential to understand the specific conditions it is intended to treat and to ensure it is appropriate for the individual's medical needs. As with any medication, there may be potential side effects or interactions with other drugs, so it is important to consult with a healthcare professional before starting treatment. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of Sodium Citrate 8.8% Oral Liquid.

Other Uses

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Aside from its common application in the treatment of certain disease states, Sodium Citrate 8.8% Oral Liquid can have several other uses. This formulation is also utilized as a systemic and urinary alkalizer, which means it can help to reduce the acidity of the urine and the blood. Consequently, this property makes it useful for patients who need to manage their urinary pH, such as those with renal tubular acidosis or to prevent certain kinds of kidney stones. Moreover, sodium citrate can be employed during surgery as a part of a prophylactic regimen to prevent acidosis and electrolyte imbalance resulting from blood transfusions or when there is a risk of lactic acid buildup.

Furthermore, because this medication can increase gastric pH, it may be used off-label for relief of discomfort in patients suffering from gastric acidity or gastroesophageal reflux disease (GERD), though it's essential that this application be driven by a healthcare provider's advice. It can also be used as an expectorant, due to its ability to break down mucus, helping patients with productive cough as part of their symptom management. Additionally, sodium citrate has been associated with enhancing physical performance by acting as a buffering agent, potentially decreasing fatigue during intense exercise; however, this is more relevant to sports medicine and should only be pursued under professional guidance.

It's important to highlight that the use of sodium citrate should be based on the evaluation of a healthcare professional, and its administration must consider the patient's clinical condition, potential drug interactions, and possible contraindications. If you are a patient or prescriber with questions about the additional applications of Sodium Citrate 8.8% Oral Liquid or its suitability for an alternative indication, please reach out to us at Bayview Pharmacy for professional advice tailored to your specific needs.

Frequently Asked Questions

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What is Sodium Citrate 8.8% Oral Liquid used for?

Sodium Citrate 8.8% Oral Liquid is commonly used to make the urine less acidic. This helps the kidneys remove uric acid from the body and can prevent certain types of kidney stones and gout conditions. It may also be used for other conditions as determined by a healthcare professional.

How should I take Sodium Citrate 8.8% Oral Liquid?

The liquid should be taken orally as prescribed by your healthcare provider. The dosage is dependent on your medical condition and response to treatment. It is important to follow the specific instructions provided with your prescription for the most effective results.

Can children take this medication?

Yes, the formulation is often suitable for pediatric use, but it must be prescribed by a healthcare professional who will determine the appropriate dosage for the child's weight and medical condition.

Is this formulation suitable for elderly patients?

Yes, Sodium Citrate 8.8% Oral Liquid is often used for geriatric patients, especially for those who have difficulty swallowing solid dosage forms. However, the dose for elderly patients should be carefuly adjusted based on renal function and overall health status.

What should I do if I miss a dose?

If you miss a dose of the medication, take it as soon as you remember. However, if it is near the time of your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Are there any possible side effects?

Side effects may include stomach pain, nausea, diarrhea, and swelling or tingling in the hands or feet. If any of these effects persist or worsen, or if you experience any serious side effects such as muscle weakness or mood changes, contact your doctor promptly.

Can I take this medication with food?

Sodium Citrate 8.8% Oral Liquid can be taken with or without food. However, for best results, take it on an empty stomach or as directed by your healthcare provider.

How should I store Sodium Citrate 8.8% Oral Liquid?

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets, and do not freeze the liquid unless required by the packaging.

Can I mix this medication with other liquids?

It is advisable to take the medication as directed by your healthcare provider. If you have difficulty taking the medication, or for pediatric administration, consult your healthcare provider or pharmacist for guidance on mixing it with other liquids.

What should I avoid while taking Sodium Citrate 8.8% Oral Liquid?

While taking this medication, avoid large amounts of milk or dairy products, as these may decrease its effectiveness. Your healthcare provider may also advise you to avoid certain foods that may interact with the medication.

Do I need to follow any special dietary instructions while taking this medication?

Your healthcare provider may provide you with specific dietary instructions to help prevent kidney stones. This could involve advice on fluid intake, dietary changes, and avoiding certain foods high in calcium or oxalate.

When will I know if the medication is effective?

The effectiveness of the medication can vary based on the individual's condition. Follow up with your healthcare provider as recommended to monitor your progress and discuss any concerns or questions about the effectiveness of the treatment.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.