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Sulfasalazine 250 mg Suppository

Sulfasalazine 250 mg Suppository is a solid dosage form designed for insertion into a body cavity, typically the rectum or vagina. Upon dissolution or melting, it releases the medication for local or systemic absorption. This formulation is commonly used in the treatment of conditions such as Ulcerative Colitis, Crohn's Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis.

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Formula Information

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Sulfasalazine 250 mg Suppository is a prescription medication specifically formulated to treat various inflammatory diseases such as ulcerative colitis, Crohn's disease, and rheumatoid arthritis. This medication is administered rectally, designed to slowly and steadily release the active ingredient, sulfasalazine, over a period of time. This method of administration allows for a more consistent therapeutic effect compared to oral formulations.

Sulfasalazine is an anti-inflammatory drug that functions by inhibiting the production of certain inflammatory mediators. It is believed to reduce inflammation by blocking the production of leukotrienes and prostaglandins, both of which play a significant role in the inflammatory process.

The suppository formulation of sulfasalazine has proven to be an effective treatment for inflammatory diseases. It has been shown to alleviate symptoms and enhance the quality of life for patients suffering from ulcerative colitis, Crohn's disease, and rheumatoid arthritis. This medication is generally well-tolerated, with the most common side effects being mild gastrointestinal upset and skin rash.

If you have any questions or concerns regarding the use of Sulfasalazine 250 mg Suppository, please do not hesitate to contact us at Bayview Pharmacy. Our team of experienced compounding pharmacists is here to assist you in making the best decisions for your health.

Drug Interactions

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Sulfasalazine 250 mg suppository is a solid dosage form designed for insertion into a body cavity, typically the rectum or vagina. Once inserted, it dissolves or melts to release the medication for local or systemic absorption. This formulation is primarily used in the treatment of ulcerative colitis, Crohn's disease, and rheumatoid arthritis.

It is crucial to note that sulfasalazine suppositories should not be used by patients with a known hypersensitivity to sulfonamides. Special caution should be exercised when administering sulfasalazine suppositories to patients with renal or hepatic impairment, as well as those with a history of blood dyscrasias.

Patients using sulfasalazine suppositories should be closely monitored for signs and symptoms of adverse reactions. These may include nausea, vomiting, abdominal pain, rash, and fever. Additionally, signs of hematologic toxicity such as anemia, leukopenia, thrombocytopenia, and neutropenia should be vigilantly observed.

Patients are advised to promptly report any signs or symptoms of adverse reactions to their healthcare provider. This ensures timely intervention and management of potential complications. It is always recommended to consult with a healthcare provider before starting any new medication, including sulfasalazine suppositories.

How Does it Work

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Sulfasalazine 250 mg Suppository is a potent medication primarily used in the management of various inflammatory diseases such as ulcerative colitis, Crohn's disease, and rheumatoid arthritis. It functions by mitigating inflammation within the body and suppressing the activity of the immune system. This suppository form of sulfasalazine is designed to be inserted into the rectum, where it dissolves or melts, allowing the medication to be absorbed into the bloodstream and distributed throughout the body. This form is often utilized when other forms of the medication are not well-tolerated or prove ineffective.

Typically, Sulfasalazine 250 mg Suppository is used in conjunction with other medications to effectively treat inflammatory diseases. It is crucial to adhere to the medication regimen as prescribed by your healthcare provider and to follow all instructions provided on the label. If you are pregnant or breastfeeding, it is essential to inform your doctor, as sulfasalazine may not be safe for use in these circumstances.

Like most medications, Sulfasalazine 250 mg Suppository may cause side effects, which can include nausea, vomiting, diarrhea, and abdominal pain. In some cases, it may also trigger an allergic reaction, symptoms of which can include a rash, itching, and difficulty breathing. If you experience any of these side effects, it is important to contact your healthcare provider immediately.

If you have any queries or concerns about Sulfasalazine 250 mg Suppository or its mechanism of action, please do not hesitate to reach out for further information. It is our goal to ensure you are fully informed about your medication and its effects.

Other Uses

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Sulfasalazine 250 mg suppository is a solid dosage form designed for insertion into a body cavity, typically the rectum or vagina. Once inserted, it dissolves or melts to release the medication for local or systemic absorption. This formulation is primarily used to treat a variety of inflammatory conditions such as proctitis, proctosigmoiditis, and enteritis. It is also effective in managing other conditions including ulcerative colitis, Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis.

However, it is crucial to note that sulfasalazine suppositories should not be used in patients with a known hypersensitivity to sulfonamides. It is also contraindicated in patients with a history of renal impairment or severe hepatic impairment. Regular monitoring for signs of adverse reactions is necessary when using this medication. These reactions may include nausea, vomiting, abdominal pain, and rash. If any of these symptoms occur, patients are advised to immediately contact their healthcare provider.

It is always important to use this medication under the guidance of a healthcare provider. If you have any questions or concerns about the use of sulfasalazine suppositories, do not hesitate to seek professional advice. Remember, your health and safety are of utmost importance.

Frequently Asked Questions

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What is a Sulfasalazine 250 mg Suppository?

A Sulfasalazine 250 mg Suppository is a solid dosage form of medication that is inserted into a body cavity, typically the rectum or vagina. It dissolves or melts in the body to release the medication for local or systemic absorption.

How does a Sulfasalazine 250 mg Suppository work?

The suppository works by dissolving or melting once inserted into the body. The medication is then released and absorbed by the body either locally or systemically, depending on the intended use.

How should I use a Sulfasalazine 250 mg Suppository?

The suppository should be inserted into the rectum or vagina as directed by your healthcare provider. It is typically used once or twice a day, or as directed by your doctor.

What are the potential side effects of a Sulfasalazine 250 mg Suppository?

Side effects can vary depending on the individual and the condition being treated. Common side effects may include mild discomfort or irritation at the site of insertion. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Can I use a Sulfasalazine 250 mg Suppository if I am pregnant or breastfeeding?

Always consult your healthcare provider before using any medication while pregnant or breastfeeding. They will be able to advise you on the potential risks and benefits.

Can I use a Sulfasalazine 250 mg Suppository with other medications?

It's important to inform your healthcare provider about all the medications you are currently taking, as some drugs may interact with Sulfasalazine. Your healthcare provider will be able to advise you on any potential interactions.

What should I do if I miss a dose of Sulfasalazine 250 mg Suppository?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

How should I store Sulfasalazine 250 mg Suppository?

Store the suppositories in a cool, dry place, away from heat and direct light. Do not freeze them unless required by package insert. Keep medicines away from children and pets.

What should I do in case of an overdose?

If you suspect an overdose, seek immediate medical attention or call a poison control center right away.

What conditions does Sulfasalazine 250 mg Suppository treat?

Sulfasalazine is used to treat a certain type of bowel disease called ulcerative colitis. It helps to reduce inflammation, diarrhea, and rectal bleeding. Always consult your healthcare provider for more information.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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