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Vitamin K1 10% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Phytonadione

Vitamin K1 10% Topical Cream is a semisolid preparation intended for cutaneous use. It is dispensed in a pump mechanism, which allows for convenient and controlled application. This formulation is designed to deliver a localized treatment of Vitamin K1 directly to the skin, where it may be absorbed for systemic effects. The cream is commonly used in the management of certain skin conditions that may benefit from the pharmacological action of Vitamin K1, such as bruising due to minor trauma, and to aid in the treatment of skin disorders associated with Vitamin K deficiencies. Additionally, it may be used in the care of patients with compromised skin integrity where Vitamin K1 can play a role in supporting the natural healing process.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Phytonadione
Topical Cream
65d8c5e165f57c0ee7ecc546
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Vitamin K1, also known as phytonadione, is an essential nutrient that plays a critical role in the body's blood clotting process. The 10% Vitamin K1 Topical Cream is a specialized formulation designed to deliver a high concentration of Vitamin K1 directly to the skin. This semisolid preparation is dispensed in a pump mechanism, which allows for convenient, hygienic, and controlled application. The pump ensures that each dose is measured accurately, minimizing waste and ensuring consistency in the amount of product applied.

The topical application of Vitamin K1 is beneficial in treating several localized skin conditions. Additionally, Vitamin K1 cream may be used to help improve the appearance of skin affected by spider veins, as it can aid in reducing the visibility of these small, dilated blood vessels on the skin's surface. Moreover, there is evidence to suggest that Vitamin K1 can assist in the management of dark circles under the eyes, a condition often exacerbated by fragile capillaries and poor blood circulation.

For patients with compromised skin integrity, such as those with certain dermatological conditions or post-surgical patients, Vitamin K1 cream can support the skin's healing process. It is important to note that while Vitamin K1 is generally well-tolerated, patients should be advised to use the cream as directed by a healthcare professional. It is also crucial for prescribers to consider the patient's overall medical history, including any medications they are taking that may affect blood clotting, before recommending this topical treatment.

As compounding pharmacists at Bayview Pharmacy, we ensure that each batch of our Vitamin K1 10% Topical Cream is prepared with the highest quality ingredients and compounded according to stringent standards to ensure patient safety and efficacy. If you have any questions about this formulation or its suitability for treating specific disease states, please do not hesitate to reach out to us. We are here to provide comprehensive information and support to both patients and prescribers considering the use of this specialized medication.

Drug Interactions

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Vitamin K1, also known as phytonadione, is a fat-soluble vitamin that plays a critical role in the body's blood clotting process. When formulated as a 10% topical cream, it is primarily used for its potential benefits in treating certain skin conditions, such as bruising, and may aid in the healing of wounds or skin irritations. However, it is important to consider potential drug interactions when using this topical formulation.

Patients should be aware that Vitamin K1 can interact with anticoagulant medications, such as warfarin. These medications work by inhibiting the clotting effects of Vitamin K, and the use of a Vitamin K1 topical cream may reduce the effectiveness of anticoagulants, potentially leading to an increased risk of clotting. It is crucial for patients on anticoagulant therapy to consult with their healthcare provider before using this topical cream.

Additionally, topical Vitamin K1 may theoretically interact with other topical agents that affect blood clotting, such as topical nonsteroidal anti-inflammatory drugs (NSAIDs). While the systemic absorption of Vitamin K1 from a topical formulation is expected to be minimal, caution is advised when used concurrently with other topical preparations that may have an impact on coagulation.

Retinoids and peroxides, commonly found in acne treatments, may also interact with Vitamin K1 cream. These substances can alter the skin barrier and potentially affect the absorption and efficacy of Vitamin K1 when applied topically. Patients using any topical acne medications should discuss the use of Vitamin K1 cream with their healthcare provider to ensure compatibility.

It is also important to note that while Vitamin K1 is involved in the synthesis of certain proteins required for bone metabolism, the use of Vitamin K1 cream for bone health has not been well established. Patients with osteoporosis or other bone-related conditions should follow the advice of their healthcare provider regarding appropriate treatments.

Patients should inform their healthcare provider of all medications, supplements, and topical products they are currently using to avoid potential interactions. This includes over-the-counter medications, herbal supplements, and any other topical treatments. If you experience any unusual symptoms or side effects while using Vitamin K1 topical cream, contact your healthcare provider immediately.

For prescribers, it is essential to review the patient's medication profile for potential interactions with Vitamin K1 topical cream. Monitoring may be necessary when initiating or discontinuing this treatment in patients on anticoagulant therapy. Adjustments to the dosage of the anticoagulant may be required, and the patient's coagulation status should be closely monitored.

If you have any questions or require further information regarding the use of Vitamin K1 10% Topical Cream and its potential drug interactions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing you with the necessary support and guidance to ensure the safe and appropriate use of this formulation.

How Does it Work

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Vitamin K1, also known as phylloquinone, is a fat-soluble vitamin that plays a critical role in the body's blood clotting process. When formulated into a 10% topical cream, Vitamin K1 can be applied directly to the skin, where it may help to address certain conditions related to bruising, spider veins, and potentially to improve the appearance of skin affected by scars or dark circles under the eyes. The mechanism by which Vitamin K1 works involves its essential role in the synthesis of certain proteins required for blood coagulation. By aiding in the activation of these proteins, Vitamin K1 helps to regulate clot formation, which is crucial for the healing of bruises and other skin imperfections.

The semisolid preparation of Vitamin K1 10% Topical Cream is specifically designed for ease of use and precise application. The cream is dispensed from a pump mechanism, which allows for controlled dosing and minimizes the risk of contamination that can occur with jar packaging. This delivery system ensures that a consistent amount of product is applied to the skin with each use. When the cream is applied topically, the Vitamin K1 is absorbed through the skin, directly targeting the affected area. This localized treatment can be beneficial for patients who require the therapeutic effects of Vitamin K1 on specific areas of the skin without systemic exposure.

For patients with bruising, the application of Vitamin K1 cream may accelerate the healing process by facilitating the body's natural clotting pathway. In cases of spider veins, the cream may help to strengthen capillary walls, reducing the appearance of these small, dilated blood vessels. While the evidence for the treatment of dark circles and scars is more anecdotal, some patients may observe an improvement in skin tone and texture with regular use of the cream.

It is important for both patients and prescribers to understand that while Vitamin K1 10% Topical Cream can be beneficial for certain skin conditions, its effectiveness may vary from person to person. Factors such as the severity of the condition, skin type, and the presence of other medical issues can influence the results. Additionally, patients should be advised to use the cream as directed and to discuss any concerns or questions with their healthcare provider. For optimal results, the cream should be applied consistently over a period of time, and patients should follow any specific instructions provided by their prescriber regarding application frequency and duration of use.

If you have any questions or require further information about the Vitamin K1 10% Topical Cream formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide support and guidance to ensure the safe and appropriate use of this product.

Other Uses

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Vitamin K1, also known as phytonadione, is primarily recognized for its essential role in the activation of clotting factors in the blood to aid in the prevention of bleeding. However, when formulated into a 10% topical cream, its utility extends beyond this conventional application. Vitamin K1 topical cream can be beneficial in the management of skin conditions that are characterized by bruising or blood vessel fragility. It has also been utilized cosmetically to help decrease the appearance of dark circles under the eyes, as it may assist in reducing the visibility of blood vessels that contribute to discoloration. Furthermore, Vitamin K1 has been implicated in the healing process of skin; thus it may aid in the repair of skin affected by surgery, cosmetic procedures, or accidental trauma.

In dermatology, this cream could potentially be used off-label to support skin healing in patients with conditions presenting with minor petechiae or ecchymosis due to minor trauma or vascular fragility. The antioxidant properties of Vitamin K may also be of interest in skin care formulations aimed at protecting the skin from oxidative stress. This 10% concentration allows for targeted local application with the pump mechanism ensuring a consistent dose per application, which is particularly useful for ensuring even product distribution and adherence to the recommended dosing regimen.

Any claims of utility in these other uses must be taken with the caveat that evidence may be limited, and not all potential applications have been thoroughly investigated or validated in clinical studies. Therefore, prescribers and patients are encouraged to use this product based on the current available evidence and consider individual patient responses to treatment. It is important to note that while Vitamin K1 can aid in the resolution of bruising, this topical application should not be seen as a replacement for systemic therapy where it is indicated. If you have any questions regarding other possible indications for Vitamin K1 10% Topical Cream or specific concerns about its application in your particular clinical scenario, please reach out to us at Bayview Pharmacy. We are here to provide expert advice and support to ensure the best care for your patients.

Frequently Asked Questions

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What is Vitamin K1 10% Topical Cream used for?

Vitamin K1 10% Topical Cream is used for the localized treatment of certain skin conditions and to promote the absorption of the vitamin K1 through the skin. The active ingredient may help in reducing the appearance of bruising, spider veins, and other similar skin concerns.

How do I use the Vitamin K1 10% Topical Cream?

To use the cream, apply a small amount onto the affected area using the pump mechanism, which provides a controlled dosage. Gently rub the cream into the skin until it is fully absorbed. Follow the dosing instructions provided by your healthcare provider.

Is the cream safe to use on all skin types?

While Vitamin K1 10% Topical Cream is generally safe, individuals with sensitive skin or specific allergies should consult their healthcare provider before use. Always patch-test the cream on a small area first to check for any adverse reactions.

How often should Vitamin K1 10% Topical Cream be applied?

The frequency of application depends on your specific condition and the advice of your healthcare provider. It is important not to exceed the recommended dose to avoid possible side effects.

Can I use this cream on my face?

Vitamin K1 10% Topical Cream may be used on the face unless otherwise advised by your healthcare provider. However, care should be taken to avoid contact with the eyes, nose, and mouth.

What should I do if I miss a dose?

If you miss a dose of the cream, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular application schedule. Do not double the dose to catch up.

Are there any side effects associated with Vitamin K1 10% Topical Cream?

Some individuals may experience side effects such as localized skin irritation, redness, or itching. If you experience any severe side effects or signs of an allergic reaction, discontinue use immediately and consult your healthcare provider.

Can I apply makeup over the cream?

Allow the Vitamin K1 10% Topical Cream to absorb completely before applying makeup. It is advisable to wait a few minutes to ensure that the cream has fully penetrated the skin.

Should I use the cream before or after other skin care products?

Generally, it is best to apply the Vitamin K1 10% Topical Cream to clean skin before using other skin care products. This can help ensure maximum absorption of the active ingredient. Consult with your healthcare provider for specific instructions.

Can I go into the sun after applying this cream?

Exposure to sunlight can affect the efficacy and safety of the product. It is advisable to apply sunscreen or protective clothing over the treated area to protect the skin if you plan to go outdoors.

How should I store the Vitamin K1 10% Topical Cream?

Store the cream at room temperature away from direct sunlight and heat. Keep the pump mechanism tightly closed when not in use to maintain the product's integrity and avoid contamination.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Vitamin K1 10% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)

Twice daily