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Active pharmaceutical ingredient

Sodium Valproate

Sodium Valproate is a widely utilized active pharmaceutical ingredient known for its efficacy in managing neurological conditions, particularly epilepsy and bipolar disorder.

Compounded to order
Prescription required

About this ingredient

Sodium Valproate is a widely utilized active pharmaceutical ingredient known for its efficacy in managing a variety of neurological and psychiatric conditions. As a derivative of valproic acid, it primarily functions as an anticonvulsant and mood-stabilizing agent, making it a cornerstone in the treatment of epilepsy, bipolar disorder, and migraine prophylaxis.

Its mechanism of action involves increasing the levels of gamma-aminobutyric acid (GABA) in the brain, which helps to stabilize neuronal activity and prevent seizures. Additionally, Sodium Valproate is believed to modulate the function of sodium channels and inhibit repetitive neuronal firing, further contributing to its therapeutic effects.

Prescribers often choose Sodium Valproate for its broad-spectrum efficacy, particularly in patients with mixed seizure types or those who have not responded to other treatments. It is important to monitor patients for potential side effects, which can include gastrointestinal disturbances, weight gain, and, in rare cases, hepatotoxicity or pancreatitis.

Regular blood tests are recommended to ensure therapeutic levels are maintained and to monitor liver function. Sodium Valproate is contraindicated in pregnant women due to the risk of teratogenic effects, and alternative treatments should be considered for women of childbearing potential.

In the context of compounded formulations, Sodium Valproate can be tailored to meet specific patient needs, offering flexibility in dosing and delivery methods. This customization can enhance patient adherence and optimize therapeutic outcomes, particularly in populations with unique medical requirements.

Sources and further reading

Compounded at Bayview

How we prepare this ingredient

Patient guides for the preparations we make most often. Each one is compounded to order and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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For prescribers

Full formulary with this ingredient

Every preparation in our formulary that contains this ingredient. Strength, base and dose form are set by the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.