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Aloe Vera 0.5%/Clindamycin 1%/Hydrocortisone 1%/Spironolactone 5%/Vitamin E Acetate 5% Topical Cream

This formulation is a semisolid preparation, dispensed in a pump mechanism for easy and controlled application on the skin. It contains Aloe Vera 0.5%, Clindamycin 1%, Hydrocortisone 1%, Spironolactone 5%, and Vitamin E Acetate 5%. The cream is designed for localized treatment or absorption of these active ingredients.

Aloe Vera is known for its soothing and healing properties, while Clindamycin is an antibiotic that fights bacteria in the body. Hydrocortisone is a steroid that reduces inflammation, redness, and swelling. Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. Vitamin E Acetate is a form of Vitamin E that's often found in skin care products due to its antioxidant properties.

This topical cream is used to treat a variety of disease states. The combination of these ingredients can help manage conditions such as acne, dermatitis, rosacea, and other skin inflammations. It can also be used to treat hormonal acne, thanks to the inclusion of Spironolactone. The Vitamin E Acetate and Aloe Vera in the formulation provide additional skin healing and soothing benefits.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clindamycin Hydrochloride
Hydrocortisone
Spironolactone
Vitamin E Acetate
Aloe Barbadensis Leaf Extract
Topical Cream
652fe59d91379c7faac4aff8

Formula Information

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This formulation is a unique blend of Aloe Vera 0.5%, Clindamycin 1%, Hydrocortisone 1%, Spironolactone 5%, and Vitamin E Acetate 5% in a topical cream. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

Aloe Vera, known for its soothing and healing properties, helps to reduce skin inflammation and promote healing of wounds. Clindamycin, an antibiotic, works by stopping the growth of bacteria that cause skin infections. Hydrocortisone, a corticosteroid, reduces swelling, itching, and redness that can occur in various skin conditions. Spironolactone, a potassium-sparing diuretic, is used off-label in dermatology for its anti-androgen effects. Vitamin E Acetate, a powerful antioxidant, helps to nourish and protect the skin from damage caused by free radicals.

This formulation is used to treat a variety of skin conditions, including acne, dermatitis, eczema, and other inflammatory skin conditions. It works by reducing inflammation, killing bacteria, and promoting skin healing. The combination of these active ingredients provides a comprehensive approach to skin care, addressing not only the symptoms but also the underlying causes of these conditions.

For patients, it is important to apply this cream as directed by your healthcare provider, usually to the affected skin area twice daily or as directed. Avoid contact with the eyes, nose, mouth, or open wounds. Wash your hands before and after applying this medication. If your condition does not improve or if it worsens, contact your healthcare provider.

For prescribers, it is important to note that this formulation may not be suitable for all patients, particularly those with known hypersensitivity to any of the ingredients, pregnant or breastfeeding women, or those with severe kidney disease due to the presence of spironolactone. Regular monitoring of the patient's condition is recommended to assess the effectiveness of the treatment and to detect any potential side effects.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains a combination of Aloe Vera, Clindamycin, Hydrocortisone, Spironolactone, and Vitamin E Acetate. Each of these ingredients has its own potential interactions, which can be amplified when used in combination. It's important to be aware of these potential interactions and to discuss them with your healthcare provider.

Aloe Vera is generally considered safe for topical use, but it may interact with certain medications if absorbed through the skin. These include insulin, diuretics, and corticosteroids. If you are taking any of these medications, consult your healthcare provider before using this formulation.

Clindamycin is an antibiotic that can interact with other antibiotics, particularly those in the same class. It can also interact with certain neuromuscular blocking agents, which are often used during surgery. If you are scheduled for surgery or are taking other antibiotics, inform your healthcare provider.

Hydrocortisone is a corticosteroid that can interact with other corticosteroids, as well as certain medications for diabetes, blood thinners, and medications that suppress the immune system. If you are taking any of these medications, consult your healthcare provider before using this formulation.

Spironolactone is a diuretic that can interact with other diuretics, as well as certain blood pressure medications, lithium, and certain muscle relaxants. If you are taking any of these medications, consult your healthcare provider before using this formulation.

Vitamin E Acetate is generally considered safe for topical use, but it may interact with certain medications if absorbed through the skin. These include blood thinners, cholesterol medications, and certain cancer treatments. If you are taking any of these medications, consult your healthcare provider before using this formulation.

This formulation is designed to treat a variety of skin conditions. Aloe Vera and Vitamin E Acetate provide soothing and healing properties, while Clindamycin treats bacterial infections. Hydrocortisone reduces inflammation and itching, and Spironolactone can help with hormonal acne. However, the effectiveness of this formulation can vary depending on the individual and the specific condition being treated.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to help ensure that you can use this formulation safely and effectively.

How Does it Work

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This topical cream formulation combines the therapeutic benefits of Aloe Vera, Clindamycin, Hydrocortisone, Spironolactone, and Vitamin E Acetate. Each of these ingredients plays a unique role in treating various skin conditions.

Aloe Vera, known for its soothing and healing properties, helps to reduce skin inflammation and promote healing of wounds. It also provides a cooling effect on the skin, which can help to alleviate discomfort associated with skin irritations.

Clindamycin is an antibiotic that works by stopping the growth of bacteria. It is used to treat a wide variety of bacterial skin infections. By applying it topically, it directly targets the area of infection, reducing the likelihood of systemic side effects.

Hydrocortisone is a corticosteroid that works by reducing the swelling, redness, and itching that can occur with various skin conditions. It is a common ingredient in many topical treatments for conditions such as eczema, dermatitis, allergies, and rash.

Spironolactone is a potassium-sparing diuretic that is often used orally to treat conditions like high blood pressure and heart failure. However, in this topical formulation, it is used for its anti-androgen effects, which can help to treat skin conditions like acne and hirsutism (excessive hair growth).

Vitamin E Acetate is a form of Vitamin E that is often used in skin care products for its antioxidant properties. It helps to protect the skin from damage caused by free radicals and can also help to moisturize and soothe the skin.

This formulation is dispensed in a pump mechanism, which allows for convenient and controlled application on the skin. The cream is designed to be absorbed into the skin, providing localized treatment for the affected area.

As with any medication, it may not be suitable for everyone and may cause side effects. Always consult with your healthcare provider or pharmacist before starting any new medication.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This formulation of Aloe Vera 0.5%/Clindamycin 1%/Hydrocortisone 1%/Spironolactone 5%/Vitamin E Acetate 5% Topical Cream has been primarily used for treatment of various skin conditions. However, it can also be utilized for additional purposes, thanks to its unique combination of ingredients.

For instance, clindamycin is an antibacterial that can help combat acne and decrease the number of acne lesions, while hydrocortisone is an anti-inflammatory and anti-pruritic agent used to alleviate redness, itching, and swelling. This combination could potentially be promising for individuals who experience skin irritation, inflammatory responses, or other minor dermatological discomforts.

The addition of spironolactone in the formulation might provide potential benefits to those with hormonal acne, as this medication is known for its anti-androgenic properties. Aloe vera, recognized for its soothing properties, and Vitamin E, well-known for its antioxidant and skin-nourishing benefits, can also add to the overall skin health benefits.

Although not explicitly designed as such, the formulation could potentially cater to individuals seeking a comprehensive, multi-purpose skincare product. However, it’s essential to note that this formulation should not be used as a self-prescribed remedy for skin issues that haven’t been evaluated by a healthcare provider. Overuse or misuse of corticosteroids like hydrocortisone can lead to skin thinning and other adverse effects. Similarly, overuse of antibiotics like clindamycin can lead to bacterial resistance.

Therefore, always consult your healthcare provider or a pharmacist before using this formulation for any of the mentioned alternative uses. Also, it is crucial to strictly follow the dosing regimen your healthcare provider or pharmacist recommends if prescribed this cream for off-label uses to ensure optimal efficacy and safety. Any questions or concerns about this formulation can be directed to us at Bayview Pharmacy.

Frequently Asked Questions

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What is the purpose of this topical cream?

This cream is a compounded formulation designed for convenient and controlled application on the skin. It contains Aloe Vera, Clindamycin, Hydrocortisone, Spironolactone, and Vitamin E Acetate, and it is for localized treatment or absorption of these active ingredients.

How do I apply this cream?

This cream comes in a pump mechanism. You should clean and dry the affected area first, then apply a small amount and gently rub it in. Always wash your hands after use unless the hands are the area being treated.

What are the potential side effects of this cream?

As with any medication, side effects may occur. Potential side effects of this cream can include skin irritation where the cream has been applied. If you notice any significant side effects or reactions, contact your healthcare provider immediately.

Will this cream interact with my other medications?

As this cream is applied topically, it is less likely to interact with medications taken orally. However, it is always recommended to inform your healthcare provider of all medications you're currently taking to avoid any possible interactions.

Can this cream be used by children?

You should consult your healthcare provider before using this cream on children. The safety and effectiveness of this cream in pediatric patients are currently not established.

Are the ingredients in this cream safe for sensitive skin?

While the ingredients in this cream have been chosen for their beneficial properties, everyone's skin is unique. If you have sensitive skin, it's always a good idea to spot-test new products to ensure you do not have a negative reaction. If irritation occurs, stop using the cream and consult a healthcare provider.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not apply extra to make up for a missed dose.

Can I use this cream if I am pregnant or nursing?

Consult your healthcare provider before using this cream if you are pregnant or nursing. The safety of its use during pregnancy or breastfeeding is not yet established.

Can this cream be used on all skin types?

This cream is designed to be versatile and generally suitable for all skin types. However, individual reactions may vary. Always consult with your healthcare provider if you have concerns about your skin's reaction to this cream.

How should I store this cream?

Store this cream at room temperature. Avoid exposure to extreme heat or cold. Keep the container cap tightly closed when not in use to protect the cream's effectiveness and longevity.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Aloe Vera 0.5%/Clindamycin 1%/Hydrocortisone 1%/Spironolactone 5%/Vitamin E Acetate 5% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)