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Amantadine HCl 5%/Gabapentin 5%/Lidocaine HCl 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Amantadine Hydrochloride
Gabapentin
Lidocaine Hydrochloride

This formulation is a combination of Amantadine HCl 5%, Gabapentin 5%, and Lidocaine HCl 2% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Amantadine HCl component is an antiviral medication that also has properties for treating Parkinson's disease and certain conditions caused by a virus. Gabapentin is an anticonvulsant and nerve pain medication used to treat seizures and pain caused by shingles. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. Together, these ingredients work to treat a variety of disease states, providing relief from symptoms and improving patient comfort and quality of life.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amantadine Hydrochloride
Gabapentin
Lidocaine Hydrochloride
Topical Gel
652f0973be694de78632eeaa

Formula Information

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This formulation combines three active ingredients: Amantadine HCl, Gabapentin, and Lidocaine HCl, each at different concentrations. Amantadine HCl is an antiviral medication that also has properties to relieve pain, particularly nerve pain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat seizures and pain caused by shingles. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. When these three medications are combined in a topical gel, they can provide significant relief from various types of pain.

The gel is a semisolid formulation that is dispensed through a pump mechanism. This allows for easy and precise application on the skin, ensuring that the medication is delivered exactly where it is needed. The gel-like consistency also aids in the absorption of the active ingredients, allowing them to penetrate the skin and provide targeted treatment.

This formulation can be used to treat a variety of disease states. It can be used to manage nerve pain, such as that caused by shingles or other nerve disorders. It can also be used to treat pain associated with conditions like fibromyalgia or multiple sclerosis. Additionally, it can be used to manage pain in patients with certain types of arthritis or other chronic pain conditions.

It's important to note that while this formulation can provide significant relief from pain, it is not a cure for the underlying conditions causing the pain. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

As with any medication, there may be potential side effects, and it's important to discuss these with your healthcare provider. These may include skin irritation at the application site, dizziness, or drowsiness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Remember, this formulation is for topical use only and should not be ingested or applied to the eyes or mucous membranes. Always use this medication as directed by your healthcare provider, and do not use more than the recommended dose.

If you have any questions about this formulation, or if you need further information, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your healthcare.

Drug Interactions

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This formulation combines three active ingredients: Amantadine HCl, Gabapentin, and Lidocaine HCl. Each of these medications has its own potential for drug interactions, which can be amplified when used in combination. It's important to note that while this is a topical formulation, systemic absorption can still occur, especially with prolonged use or application to large areas of skin.

Amantadine HCl is an antiviral medication that also has properties for treating Parkinson's disease and certain types of pain. It can interact with several types of medications, including anticholinergic drugs, CNS stimulants, and live vaccines. Concurrent use with anticholinergic drugs can increase the risk of side effects such as dry mouth, constipation, and urinary retention. CNS stimulants can increase the risk of seizures, while live vaccines may have reduced effectiveness.

Gabapentin is an anticonvulsant and nerve pain medication. It can interact with antacids, morphine, and hydrocodone. Antacids can reduce the absorption of gabapentin, reducing its effectiveness. Morphine and hydrocodone can increase the levels of gabapentin in the body, potentially leading to increased side effects.

Lidocaine HCl is a local anesthetic. It can interact with other local anesthetics and certain heart medications. Using multiple local anesthetics at the same time can increase the risk of systemic toxicity. Certain heart medications, such as beta-blockers and cimetidine, can increase the levels of lidocaine in the body, potentially leading to increased side effects.

This formulation is used to treat various disease states, including neuropathic pain, post-herpetic neuralgia, and certain types of chronic pain. The combination of these three medications can provide both immediate and long-term relief from pain. Lidocaine provides immediate numbing of the area, while gabapentin and amantadine work to reduce nerve pain over time.

It's important to discuss all medications, supplements, and over-the-counter products you are currently using with your healthcare provider before starting this treatment. This will help to minimize the risk of potential drug interactions. If you experience any unusual side effects while using this formulation, contact your healthcare provider immediately.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need.

How Does it Work

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The Amantadine HCl 5%/Gabapentin 5%/Lidocaine HCl 2% Topical Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from various disease states. This semisolid formulation is dispensed through a pump mechanism, allowing for easy and precise application on the skin.

Amantadine HCl is an antiviral medication that also has properties as an antiparkinsonian drug. It works by blocking the action of certain chemicals in the brain that may contribute to the symptoms of Parkinson's disease. In this formulation, it is used for its potential analgesic effects, although the exact mechanism is not fully understood.

Gabapentin is a medication primarily used to treat seizures and neuropathic pain. It works by affecting the way the body senses pain. Gabapentin is thought to reduce the release of substances that transmit pain signals in the brain and spinal cord, thereby reducing the perception of pain.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. When applied topically, it causes a temporary loss of feeling in the skin and surrounding area. It is used to relieve pain and discomfort from a wide range of skin conditions, or to numb the skin before certain procedures.

When these three medications are combined in a topical gel, they work together to provide targeted relief from pain and discomfort. The gel formulation allows for direct application to the affected area, ensuring that the active ingredients are delivered where they are needed most.

This formulation is particularly useful in treating conditions such as neuropathic pain, post-herpetic neuralgia, and certain types of chronic pain. It may also be used in the management of symptoms associated with conditions like Parkinson's disease. However, it's important to note that the effectiveness of this formulation can vary between individuals, and it should be used under the guidance of a healthcare professional.

If you have any questions about this formulation, or if you would like more information on how it can be used in your specific situation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Amantadine HCl, Gabapentin, and Lidocaine HCl combined in a topical gel formulation have been used effectively to alleviate the symptoms of various pain syndromes. However, this potent combination can be utilized in other therapeutic scenarios. For instance, one off-label use of this formulation could be to alleviate chronic neuropathic pain conditions. These might include diabetic peripheral neuropathy, postherpetic neuralgia, or fibromyalgia. In these disorders, patients often suffer from persistent pain, and this topical formulation has the potential to provide local and systematic relief.

Furthermore, this formulation has potential to mitigate symptoms of certain types of localized skin irritation. For example, patients who may experience dermatoses or pruritus may find relief with this formulation. It's also significant to note that this preparation could be used to provide post-surgical pain relief on the surface of the healed surgical area, providing a non-invasive alternative to systemic analgesic medications.

In relation to neurologic disorders, it has been noted that Amantadine HCl can contribute to the relief of certain symptoms associated with Parkinson's disease, a progressive nervous system disorder that affects movement. While the topical application of this medication does not offer the same systemic benefits, it can certainly provide localized relief for muscle stiffness and cramping that can be a significant problem for these patients.

Despite the numerous potential uses of this formulation, it should be used judiciously and under the supervision of a qualified healthcare provider. It is crucial to remember that while this formulation carries fewer risks of systemic side effects than oral medications, local side effects can still occur. Patients should be instructed to apply this gel as directed by their healthcare provider, and to immediately report any adverse reactions such as rash, blistering, or progressively worsening pain.

If you are a patient or a prescriber and you have further questions regarding this formulation, its uses, or its potential side effects, do not hesitate to reach out to our knowledgeable team of compounding pharmacists at Bayview Pharmacy. We are always on hand to provide expert advice and support.

Frequently Asked Questions

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What is Amantadine HCl 5%/Gabapentin 5%/Lidocaine HCl 2% Topical Gel?

It's a compounded formulation of amantadine, gabapentin, and lidocaine in a semisolid format. It is dispensed through a pump for easy and precise application on the skin. The active compounds are delivered through a gel-like consistency for targeted treatment.

How do I apply the product?

Use the pump mechanism to dispense the formulation onto your skin and rub it in gently, targeting the area in need of treatment. Strictly follow the dosage instructions given by your healthcare provider.

Can I use this on open wounds or damaged skin?

No. This product is meant for topical use on normal, intact skin. Avoid application on open wounds or damaged skin unless specifically instructed by a healthcare professional.

What is the purpose of the three ingredients in the formulation?

Amantadine, Gabapentin, and Lidocaine each play distinct roles. Amantadine helps to alleviate pain, Gabapentin assists in nerve pain relief, and Lidocaine works as a local anesthetic, providing numbness to the area where the gel is applied.

Can this formulation treat all types of pain?

It is primarily designed to treat nerve pain and offer local anesthesia. However, the effectiveness of this formulation may vary depending on the individual's condition and response to treatment. Always use under the supervision of a healthcare provider.

Is this formulation safe for pregnant or breastfeeding women?

Always consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

What is the texture of this product? Can I wear it under clothing?

This product has a gel-like consistency, which allows for smooth application and absorption into the skin. It should not pose a problem when worn under clothing, but avoid tight or restrictive garments over the area to prevent irritation.

Does the product have a scent?

Typically, such formulations are made with minimal or no added fragrance to avoid potential sensitivities or allergenic reactions. However, you may notice a faint medicinal smell.

Can children use this product?

This is a specialized medication and should only be used on children if prescribed by a healthcare provider. Always follow your doctor's instructions when using this formulation on children.

Can I use other topical products while using this gel?

Before using other topical products, consult with your healthcare provider to ensure that there will not be any interactions or potentially harmful effects.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amantadine HCl 5%/Gabapentin 5%/Lidocaine HCl 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)