Sublingual Semaglutide (generic Ozempic®) now available! Get Started
Dashboard
Formulas

Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 20 mg Oral Capsules

Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 20 mg Oral Capsules are a solid dosage form composed of two gelatin or vegetarian shells that enclose the active ingredients. This formulation is designed for easy swallowing and ensures a precise dosage of Apomorphine HCl, Phentolamine Mesylate, and Tadalafil. These active ingredients are used in the treatment of various disease states, including Parkinson's disease, erectile dysfunction, and hypertension. The combination of these medications in a single capsule provides a convenient and effective treatment option for patients.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Are you a prescriber? Sign Up
Trusted by 60,357 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Capsules
6531658ec9bfff85451220dd
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This formulation combines Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in a solid dosage form, specifically oral capsules. The capsules are composed of two gelatin or vegetarian shells that enclose the medication. This design allows for convenient and easy swallowing, and provides a precise dosage of the active ingredients.

Apomorphine HCl is a non-selective dopamine agonist that is used for the treatment of Parkinson's disease. It works by stimulating dopamine receptors in the brain, which helps to improve motor function. However, in this formulation, it is used for its emetic properties to induce vomiting in cases of poisoning or overdose.

Phentolamine Mesylate is an alpha-adrenergic blocker that is typically used to manage pheochromocytoma, a rare adrenal gland tumor. It works by blocking the action of certain nerve impulses to blood vessels, which relaxes the blood vessels and allows blood to flow more easily. In this formulation, it is used to treat erectile dysfunction.

Tadalafil is a phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). It works by relaxing the muscles and increasing blood flow to particular areas of the body.

This combination of Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in a single oral capsule provides a comprehensive approach to managing erectile dysfunction. The precise dosage of each active ingredient ensures optimal efficacy and minimizes potential side effects.

It is important for patients and prescribers to understand that this formulation should be used under the supervision of a healthcare provider. Patients should inform their healthcare provider of all medications they are currently taking, as well as any medical conditions they have, to ensure this formulation is safe for them to use.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

A small arrow pointing down

This formulation combines Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in a solid dosage form. These active ingredients work together to treat conditions such as erectile dysfunction and Parkinson's disease. Apomorphine HCl is a dopamine agonist that helps to improve motor function in patients with Parkinson's disease. Phentolamine Mesylate is an alpha-adrenergic blocker that helps to relax and widen blood vessels, improving blood flow. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that also helps to increase blood flow, particularly to the penis, aiding in the treatment of erectile dysfunction.

While this formulation can be highly effective, it's important to be aware of potential drug interactions. Apomorphine HCl can interact with certain antiemetics, such as ondansetron, increasing the risk of severe hypotension and loss of consciousness. It can also interact with antihypertensive drugs, leading to an increased risk of hypotension. Alcohol and other CNS depressants can enhance the sedative effects of Apomorphine HCl.

Phentolamine Mesylate can interact with beta-blockers, leading to an increased risk of hypotension and tachycardia. It can also interact with erectile dysfunction drugs, potentially causing priapism, a prolonged and painful erection. Additionally, it can interact with MAO inhibitors, increasing the risk of hypertensive crisis.

Tadalafil can interact with nitrates, leading to a significant drop in blood pressure. It can also interact with alpha-blockers, increasing the risk of hypotension. Other PDE5 inhibitors and HIV protease inhibitors can increase the plasma concentration of Tadalafil, potentially leading to an increase in side effects.

It's crucial for patients to inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This will help to avoid potential drug interactions and ensure the safe and effective use of this formulation.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to help.

How Does it Work

A small arrow pointing down

The Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 20 mg Oral Capsules are a combination medication designed to treat erectile dysfunction. Each of the three active ingredients plays a unique role in managing this condition.

Apomorphine HCl is a dopamine agonist that works by activating dopamine receptors in the brain. This action helps to stimulate the parasympathetic nervous system, which is responsible for causing an erection. It does this by increasing the signals to the penis to enhance blood flow, which can help to facilitate an erection.

Phentolamine Mesylate is an alpha-adrenergic blocker. It works by blocking the alpha-adrenergic nerves. These nerves can constrict the blood vessels, so by blocking them, Phentolamine Mesylate helps to increase blood flow to the penis, aiding in achieving and maintaining an erection.

Tadalafil is a type of medication known as a phosphodiesterase-5 (PDE5) inhibitor. It works by blocking the enzyme phosphodiesterase-5, which can cause the blood vessels in the penis to contract and become narrow. By inhibiting this enzyme, Tadalafil helps to relax and widen these blood vessels, which can increase blood flow to the penis and help to facilitate an erection.

The medication is encapsulated in a solid dosage form composed of two gelatin or vegetarian shells. This design allows for convenient and easy swallowing, and provides a precise dosage of the active ingredients. The capsules are designed to dissolve in the stomach, releasing the medication for absorption into the bloodstream.

It's important to note that this medication does not cause an erection on its own. Sexual stimulation is still necessary to achieve an erection even when taking this medication. The medication simply aids the body's natural processes that allow an erection to occur.

As with any medication, it's important to discuss potential side effects and interactions with your healthcare provider. This medication may not be suitable for everyone, particularly those with certain pre-existing conditions or those taking certain other medications.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

A small arrow pointing down

This Apomorphine HCl, Phentolamine Mesylate, and Tadalafil formulation is primarily utilized for managing erectile dysfunction and other related conditions. It's designed to boost blood flow to the penile area, thereby facilitating an erection in response to sexual stimulation.

Beyond its primary indication, the formulation may have other unorthodox applications. Apomorphine HCl, one ingredient in the formulation, acts as a dopamine agonist and can stimulate dopamine receptors in the body. This could potentially be helpful for situations outside of erectile dysfunction, such as Parkinson's disease. However, it's important to note that the use of this medication for this purpose is still under research and hasn't been widely established.

Tadalafil, another active component of the formula, is also indicated for benign prostatic hyperplasia (BPH), a condition which leads to an enlarged prostate gland. It can alleviate symptoms such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently. Additionally, Tadalafil is also used to treat pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness).

Keep in mind that these potential other uses should only be considered under the direct supervision of a healthcare provider. Patient-specific factors, such as other medication use, comorbid conditions, and overall health, should all be taken into account when considering these other uses.

If you have any further questions about this formulation, whether about its primary uses or potential other uses, don't hesitate to contact us at Bayview Pharmacy. We're here to provide the most accurate and up-to-date information about the medications we compound.

Frequently Asked Questions

A small arrow pointing down

What is Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 20 mg Oral Capsules?

This is a compound medication packaged in either gelatin or vegetarian capsules. Each capsule contains precise doses of three active ingredients: Apomorphine HCl, Phentolamine Mesylate, and Tadalafil. The design of the capsule allows you to swallow the medication easily.

How does this compound medication work?

The active ingredients in this compound medication work together to treat specific health conditions. However, the effectiveness and mechanism of action can vary from person to person, depending on their physiology and the nature of their health condition. Always consult your healthcare provider to understand how this medication is supposed to work for you.

What are the key ingredients in these capsules?

This compound medication contains Apomorphine HCl (1mg), Phentolamine Mesylate (2mg), and Tadalafil (20mg). These are the active ingredients enclosed by either a gelatin or a vegetarian shell to form a solid dosage form.

What is the benefit of these capsules being in a solid dosage form?

Solid dosage forms, like capsules, provide accurate dosages of the active ingredients. They are convenient and easy to swallow, ensuring that patients who have difficulty taking medication find it easier to adhere to their treatment routine.

What is the difference between vegetarian and gelatin shells?

Gelatin shells are derived from animal sources, while vegetarian shells are made from plant sources. This is specially designed to cater to the diverse dietary practices and preferences of patients who need to take this compounded formulation.

Should I swallow the capsule whole or can I open it?

These capsules should be swallowed whole. They are designed as such to ensure that you receive precise dosages of the active ingredients. Opening or breaking them may alter the intended effects of the medication.

How should I store these capsules?

You should typically store these capsules in a cool, dry place away from direct sun exposure. However, always refer to the particular storage instructions provided by your pharmacist or healthcare provider.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Never take two doses at one time.

Can I take these capsules with food?

The necessity to take this medication with or without food depends on the directive of your healthcare provider. Some medications may require food to aid in absorption while others may need to be taken on an empty stomach.

Are there any side effects of this compounded formulation?

All medications can have side effects. The type and severity of side effects may vary from person to person. Always consult with your healthcare provider about the potential side effects and monitor your condition regularly.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
NEW PRESCRIPTION ORDER FORM
1
Circle for steps.
Patient Information
2
Circle for steps.
Prescriber and Prescription Information
3
Circle for steps.
Fax order form to Bayview Pharmacy at 401-284-4506.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.