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Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 3%/Gabapentin 6% Topical Gel

This formulation is a semisolid compound, Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 3%/Gabapentin 6% Topical Gel, dispensed through a pump mechanism for easy and precise application. The gel-like consistency allows for targeted treatment or absorption of the active ingredients directly through the skin.

The combination of Baclofen, Bupivacaine HCl, Diclofenac Sodium, and Gabapentin in this formulation is designed to treat a variety of disease states. Baclofen is a muscle relaxer and an antispastic agent, Bupivacaine HCl is a local anesthetic, Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), and Gabapentin is an anticonvulsant and nerve pain medication. Together, these ingredients work to alleviate symptoms associated with conditions such as muscle spasms, nerve pain, inflammation, and localized pain.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Bupivacaine Hydrochloride
Diclofenac Sodium
Gabapentin
Baclofen
Topical Gel
6537e6feaa0913a0b4b6881d

Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Bupivacaine HCl 1%, Diclofenac Sodium 3%, and Gabapentin 6%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses, thereby reducing pain and discomfort. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body. Gabapentin is an anticonvulsant and nerve pain medication that is used to treat nerve pain and discomfort.

It can be used to manage conditions such as neuropathic pain, musculoskeletal pain, inflammation, and spasticity. The topical application allows for targeted treatment, reducing systemic side effects and providing relief directly to the affected area.

Patients using this formulation should apply it as directed by their healthcare provider, typically to the affected area 3-4 times daily. It is important to wash hands before and after application and to avoid contact with eyes, mouth, and other mucous membranes. As with any medication, potential side effects may include skin irritation or allergic reactions. Patients should report any unusual symptoms to their healthcare provider immediately.

Prescribers considering this formulation for their patients should be aware of the individual components and their potential interactions with other medications. It is also important to consider the patient's overall health status, including any kidney or liver conditions, as these may affect the metabolism and excretion of the active ingredients. Regular monitoring may be necessary to ensure the effectiveness and safety of the treatment.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Drug Interactions

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This topical gel formulation contains four active ingredients: Baclofen, Bupivacaine HCl, Diclofenac Sodium, and Gabapentin. Each of these ingredients has a specific role in managing pain and inflammation, often associated with conditions such as neuropathic pain, musculoskeletal pain, and post-surgical pain. However, it's important to be aware of potential drug interactions when using this formulation.

Baclofen is a muscle relaxant and antispasmodic agent. It may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. It's crucial to avoid or limit the use of alcohol while using this medication.

Bupivacaine HCl is a local anesthetic. It can interact with other local anesthetics and certain antiarrhythmic drugs (like lidocaine and mexiletine), potentially causing additive systemic toxicity. Patients should inform their healthcare provider about all the medications they are currently taking, including over-the-counter drugs and supplements.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). It may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of bleeding. It can also interact with certain blood pressure medications and diuretics, potentially reducing their effectiveness. Patients with a history of peptic ulcer disease or poor kidney function should use this medication with caution.

Gabapentin is an anticonvulsant and nerve pain medication. It may interact with antacids containing magnesium or aluminum, potentially reducing the absorption of gabapentin. It's recommended to take gabapentin at least 2 hours after taking an antacid. Gabapentin may also interact with central nervous system depressants, leading to increased sedation.

It's important to note that while this formulation is designed for topical use, systemic absorption can still occur, especially with prolonged use or application to large surface areas. Therefore, the potential for these drug interactions should not be overlooked.

Patients should always inform their healthcare provider about all the medications they are currently taking, including prescription drugs, over-the-counter drugs, and dietary supplements. They should also report any adverse effects they experience while using this medication. If you have any questions or concerns about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

How Does it Work

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This formulation is a combination of four active ingredients: Baclofen, Bupivacaine HCl, Diclofenac Sodium, and Gabapentin. Each of these ingredients plays a unique role in managing pain and inflammation.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. This makes it particularly useful for conditions such as multiple sclerosis and spinal cord injuries.

Bupivacaine HCl is a local anesthetic. It works by blocking nerve impulses in the body, which can help to numb the area and reduce pain. This makes it particularly useful for post-surgical pain or other conditions where local anesthesia is beneficial.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause pain and inflammation. This makes it particularly useful for conditions such as arthritis, where inflammation is a key factor in pain.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. This makes it particularly useful for conditions such as neuropathic pain, where nerve damage is a key factor in pain.

The semisolid formulation dispensed through a pump mechanism allows for easy and precise application on the skin. This targeted treatment allows for the active ingredients to be absorbed directly into the affected area, providing localized relief without the systemic side effects that can occur with oral medications.

This formulation can be used to treat a variety of disease states, including but not limited to: multiple sclerosis, spinal cord injuries, post-surgical pain, arthritis, and neuropathic pain. As with any medication, it is important to use this formulation as directed by a healthcare provider, and to discuss any potential side effects or interactions with other medications.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Other Uses

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Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 3%/Gabapentin 6% Topical Gel is primarily formulated for treating conditions that involve pain and inflammation, particularly neuropathic pain. However, the diverse active ingredients give it potential uses in managing a variety of other conditions.

Baclofen is a muscle relaxant and anti-spastic agent, while bupivacaine is a local anesthetic. This makes the formulation potentially useful in treating conditions involving muscle spasms and localized pain. Compounding pharmacists might consider its potential benefits in managing symptoms associated with spasticity like Multiple Sclerosis or stiff person syndrome. Furthermore, bupivacaine's anesthetic effects lend this formulation for uses involving temporary relief of local discomfort, such as postoperative pain or for procedural pain management in a variety of dermatological procedures.

The inclusion of diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID), extends the potential uses of this gel to conditions involving inflammation. Acute symptoms of osteoarthritis, rheumatoid arthritis, and other inflammatory joint disorders might benefit from this localized form of diclofenac. Moreover, diclofenac’s anti-inflammatory effect might also prove beneficial in treating certain types of dermatitis or skin inflammation.

Gabapentin within the formula is an anticonvulsant with neuropathic pain relieving properties. This could provide potential benefits in managing diverse neuropathic pain conditions like diabetic neuropathy, postherpetic neuralgia or fibromyalgia. It can also contribute to minimizing discomfort in conditions like restless legs syndrome or certain atypical facial pains.

It's essential to note that while Baclofen/Bupivacaine/Diclofenac/Gabapentin gel might be useful in managing these conditions, it should only be used under the guidance of a healthcare professional. Patients should always discuss potential off-label uses with their prescriber and pharmacist to assess the potential benefits and risks, as well as to ensure appropriate monitoring. Please reach out to us at Bayview Pharmacy with any further questions or for additional details about this versatile formulation.

Frequently Asked Questions

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What exactly is this compounded formulation of Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 3%/Gabapentin 6% Topical Gel?

This is a compounded medication that combines the drugs Baclofen, Bupivacaine HCl, Diclofenac Sodium, and Gabapentin in a topical gel form. It's a semisolid formulation that can be precisely applied to the skin using a pump mechanism. The active ingredients are absorbed through the skin to provide targeted treatment.

How should I apply this compounded formulation?

This formulation comes in a pump dispenser that facilitates easy application. It should be applied directly to the area of the skin as indicated by your doctor, ensuring an even cover. Always wash your hands before and after application.

What are the ingredients contained in this formulation?

This formulation includes Baclofen, Bupivacaine HCl, Diclofenac Sodium, and Gabapentin.

What conditions can this formulation treat?

This gel is often used for pain relief in patients with conditions such as neuropathic pain, and musculoskeletal problems. The precise conditions it treats will depend on the individual patient and their doctor's recommendation.

Can it be applied to broken skin?

Generally, this medication should not be applied to broken skin or open wounds. If there's a specific need, do consult with your healthcare provider before application.

Are there any side effects of using this topical gel?

Just like any other medications, it may cause side effects, although not everyone experiences them. These might include skin irritation at the site of application. More serious side effects are not common but can occur. Always seek medical advice if you notice any adverse reactions.

How often should I apply the gel?

The frequency of application will depend on your healthcare provider's instructions. It’s important to follow the prescribed dosage to achieve the desired therapeutic effect.

How long can I use this topical gel?

The duration of use will depend on the nature of your condition, response to treatment, and your healthcare provider's recommendations. Always follow your doctor's instructions.

Is it safe to use during pregnancy or breastfeeding?

If you're pregnant or breastfeeding, it's essential to discuss with your doctor before using this medication, as the active ingredients may impact the baby. Always consult your healthcare provider in such cases.

Can this formulation be used alongside other medications?

It's important to inform your healthcare provider about all other medications you're currently taking. While it's generally safe to use with most other medications, interactions are possible and your doctor will make the most informed decision about compatibility.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Baclofen 2%/Bupivacaine HCl 1%/Diclofenac Sodium 3%/Gabapentin 6% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)