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This formulation is a Bupivacaine HCl 0.5%/Ketamine HCl 1%/Ketoprofen 10% Transdermal Gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients. This formulation is designed to treat a variety of disease states, providing relief from symptoms and improving patient outcomes.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation is a compounded transdermal gel containing Bupivacaine HCl 0.5%, Ketamine HCl 1%, and Ketoprofen 10%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.
Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses, thereby reducing pain and discomfort in the applied area. Ketamine HCl, on the other hand, is a potent analgesic that provides pain relief by blocking certain receptors in the brain. Lastly, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of certain substances in the body that cause inflammation.
It can be used to treat conditions such as neuropathic pain, musculoskeletal pain, and inflammation. The localized application ensures that the medication acts directly on the affected area, reducing systemic side effects and providing targeted relief.
Patients using this formulation should apply it as directed by their healthcare provider. It is important to clean and dry the skin before application to ensure optimal absorption. The gel should not be applied to broken or irritated skin, and patients should avoid contact with eyes and mucous membranes. Any adverse reactions or side effects should be reported to the healthcare provider immediately.
Prescribers should consider the patient's overall health status, other medications, and potential drug interactions when prescribing this formulation. Regular monitoring may be necessary to assess the patient's response to treatment and adjust the dosage if necessary. As with all compounded medications, this formulation should be used under the supervision of a healthcare provider.
If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.
The combination of Bupivacaine HCl 0.5%, Ketamine HCl 1%, and Ketoprofen 10% in a transdermal gel formulation is designed to provide targeted pain relief. Bupivacaine is a local anesthetic that works by blocking nerve impulses, thereby reducing pain and discomfort. Ketamine is a general anesthetic that works on the central nervous system to produce pain relief. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain.
However, as with any medication, there are potential drug interactions that patients and prescribers should be aware of. Bupivacaine, Ketamine, and Ketoprofen can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions.
Bupivacaine may interact with certain heart medications, such as beta-blockers or calcium channel blockers, potentially leading to serious heart problems. It can also interact with other local anesthetics or sedatives, potentially increasing the risk of serious side effects such as slow or irregular heartbeat, severe drowsiness, or respiratory problems.
Ketamine may interact with central nervous system depressants, including alcohol, benzodiazepines, opioids, and barbiturates, potentially leading to increased sedation and respiratory depression. It can also interact with certain antidepressants, potentially increasing the risk of serious side effects such as high blood pressure, increased heart rate, and seizures.
Ketoprofen may interact with blood thinners, such as warfarin, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, or alcohol, potentially increasing the risk of stomach ulcers or bleeding. Furthermore, Ketoprofen may interact with certain blood pressure medications or diuretics, potentially reducing their effectiveness.
Patients should inform their healthcare provider of all medications they are currently taking, including prescription and over-the-counter medications, vitamins, and herbal supplements, to avoid potential drug interactions. They should also avoid consuming alcohol while using this medication, as it can increase the risk of stomach bleeding and other side effects.
Prescribers should carefully consider the potential drug interactions when prescribing this medication and monitor their patients closely for any signs of adverse reactions. They should also educate their patients about the potential risks and benefits of this medication, and advise them to seek immediate medical attention if they experience any unusual symptoms.
If you have any questions about this medication or its potential drug interactions, please do not hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.
The Bupivacaine HCl 0.5%/Ketamine HCl 1%/Ketoprofen 10% Transdermal Gel is a unique formulation that combines the analgesic properties of Bupivacaine, Ketamine, and Ketoprofen in a transdermal gel form. This formulation is designed to be applied topically to the skin, where it is absorbed into the body to provide targeted pain relief.
Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses in your body, thereby reducing pain and discomfort. It is often used in surgical procedures or to provide relief from chronic pain conditions. In this formulation, Bupivacaine HCl provides a local anesthetic effect, numbing the area where the gel is applied.
Ketamine HCl is a powerful analgesic that works by blocking certain receptors in the brain that are responsible for transmitting pain signals. It is often used in the management of chronic pain conditions, particularly those that have not responded to other treatments. In this formulation, Ketamine HCl enhances the pain-relieving effects of Bupivacaine HCl, providing additional relief from pain.
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is often used to relieve pain, reduce inflammation, and lower fever. In this formulation, Ketoprofen provides anti-inflammatory effects, helping to reduce swelling and inflammation in the area where the gel is applied.
The transdermal gel formulation allows for the active ingredients to be absorbed through the skin and into the body, providing targeted relief from pain and inflammation. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This makes it an ideal treatment option for patients who have difficulty swallowing pills or who prefer a non-invasive method of medication administration.
This formulation can be used to treat a variety of disease states, including chronic pain conditions, post-surgical pain, and inflammatory conditions. It provides a targeted, localized treatment option that can be tailored to the individual patient's needs.
If you have any questions about this formulation, or if you would like more information on how it can be used to treat specific conditions, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.
This is a semi-solid formulation of Bupivacaine, Ketamine, and Ketoprofen with respective concentrations. They are dispensed through a pump mechanism and applied on the skin where they are absorbed into the body.
The pump mechanism allows for an easy and precise application of the medication on the skin. It dispenses a consistent amount of the gel each time, ensuring that you are getting an accurate dose.
The gel-like consistency aids in ease of application and allows for optimum absorption of the active ingredients. It adheres well to the skin covering the target area effectively.
This gel should be stored at room temperature, away from heat, moisture, and direct light. Keep all medicine out of the reach of children.
While it can alleviate various types of pain, it is recommended to use Bupivacaine HCl 0.5%/Ketamine HCl 1%/Ketoprofen 10% Transdermal Gel under professional medical advice for targeted treatment.
Apply the missed dose as soon as you remember. However, if it's almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule.
In case of accidental ingestion, seek medical help immediately. Do not try to vomit unless directed to do so by a healthcare professional.
Like all medications, this gel can have side effects. Though not everyone gets them, it's important to seek medical advice if you notice any unusual symptoms.
If you are pregnant or breastfeeding, it's important that you seek medical advice before using Bupivacaine HCl 0.5%/Ketamine HCl 1%/Ketoprofen 10% Transdermal Gel. Your healthcare provider will guide you based on your specific needs and conditions.
Apply a thin layer of the gel to the affected area as often as directed by your healthcare provider. Do not apply more or less of it or apply it more often than prescribed by your doctor.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
