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Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is a semisolid formulation dispensed through a pump mechanism. This formulation is designed for easy and precise application on the skin, allowing for targeted treatment or absorption of the active ingredients. The gel-like consistency ensures a smooth application process.
The active ingredients, Bupivacaine HCl and Ketoprofen, work together to provide relief from various disease states. Bupivacaine HCl is a local anesthetic that helps to numb the skin and surrounding tissues, reducing pain and discomfort. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation, swelling, and pain.
The transdermal delivery allows for direct application to the affected area, providing targeted relief and minimizing systemic side effects.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation combines Bupivacaine HCl 0.5% and Ketoprofen 10% in a transdermal gel. Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses, thereby reducing pain sensation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain.
The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. This targeted treatment ensures that the active ingredients are absorbed directly into the affected area, providing localized relief from pain and inflammation. The gel-like consistency also ensures that the medication stays in place, reducing the risk of the medication spreading to unaffected areas.
This formulation is particularly useful in treating various disease states that involve pain and inflammation. These include conditions such as arthritis, bursitis, and tendonitis. It can also be used to manage pain following surgical procedures or injuries. The combination of Bupivacaine HCl and Ketoprofen provides both immediate and long-lasting relief from pain and inflammation.
Patients using this formulation should apply it as directed by their healthcare provider. It is important to avoid applying the gel to broken or irritated skin, and it should not be used in conjunction with heat pads or other heating devices, as this could increase the absorption of the medication, potentially leading to unwanted side effects.
Prescribers should consider the patient's overall health status, other medications being taken, and the specific disease state being treated when deciding on the appropriate dose and frequency of application. As with all medications, the lowest effective dose for the shortest duration should be used to minimize the risk of side effects.
If you have any questions about this formulation, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.
Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is a unique formulation designed to provide targeted pain relief. Bupivacaine HCl is a local anesthetic that works by blocking nerve signals in your body, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Together, they provide a potent combination for managing pain and inflammation.
However, like all medications, this formulation can interact with other drugs, potentially altering their effects or increasing the risk of side effects. It's crucial to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.
Specifically, Bupivacaine HCl may interact with certain medications such as other local anesthetics, antiarrhythmics (like amiodarone, mexiletine), cimetidine, and certain beta blockers (like metoprolol). These interactions can affect how Bupivacaine HCl works or increase the risk of serious side effects.
Ketoprofen, on the other hand, can interact with drugs such as aspirin, clopidogrel, corticosteroids (like prednisone), certain blood pressure medications (like ACE inhibitors, ARBs), and other NSAIDs (like ibuprofen, naproxen). These interactions can increase the risk of bleeding or kidney problems, or interfere with the effectiveness of the medications.
Furthermore, this formulation should not be used with other topical products, including creams, lotions, or gels, as they may alter the absorption of Bupivacaine HCl and Ketoprofen, potentially leading to increased side effects.
It's also important to note that alcohol and certain foods may interact with this formulation. Alcohol can increase the risk of stomach bleeding, while certain foods (like grapefruit) can affect the absorption of the medication. Always discuss your diet and alcohol consumption with your healthcare provider when starting a new medication.
Lastly, this formulation may interact with certain medical conditions. For instance, patients with a history of kidney disease, liver disease, stomach/intestinal problems (like bleeding, ulcers), heart disease (like previous heart attack), high blood pressure, stroke, blood disorders (like anemia), asthma, nasal polyps, or certain allergies (like aspirin/NSAID allergy) should use this medication cautiously.
Remember, this is not a complete list of possible drug interactions. Always consult your healthcare provider to ensure the safe and appropriate use of this medication. If you have any questions or concerns, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help!
The Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel is a unique formulation that combines the analgesic and anti-inflammatory properties of Bupivacaine and Ketoprofen, respectively. This formulation is designed to be applied topically, directly to the skin, where it is absorbed into the underlying tissues to provide targeted pain relief and inflammation reduction.
Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses in your body, thereby reducing pain sensation. It is a long-acting anesthetic that provides prolonged pain relief. When applied topically, Bupivacaine HCl numbs the skin and surrounding tissues, reducing pain and discomfort in the treated area.
Ketoprofen, on the other hand, is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, Ketoprofen can reduce inflammation and pain in the specific area of application, without the systemic side effects associated with oral NSAIDs.
The gel formulation allows for easy and precise application of the medication. The active ingredients are suspended in a gel base that facilitates absorption through the skin and into the underlying tissues. The pump mechanism allows for controlled dispensing of the medication, ensuring that the correct dose is applied each time.
This formulation is particularly useful in treating localized pain and inflammation, such as that caused by osteoarthritis, rheumatoid arthritis, bursitis, and tendonitis. It can also be used to manage post-surgical pain or pain associated with injury. By applying the medication directly to the affected area, patients can achieve targeted relief without the systemic side effects associated with oral medications.
As with any medication, it is important to use Bupivacaine HCl 0.5%/Ketoprofen 10% Transdermal Gel as directed by your healthcare provider. Avoid contact with eyes, mucous membranes, or open wounds. If you experience any adverse reactions, discontinue use and contact your healthcare provider immediately.
If you have any questions about this formulation, or if you would like more information on how it can be used to manage your specific condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
This is a compounded formulation consisting of Bupivacaine HCl and Ketoprofen. These active ingredients are combined in a gel-like consistency that's dispensed via a pump for easy application on the skin, offering a targeted treatment solution.
The unique pump design in this product’s container allows for the precisely measured amounts of the gel to be dispensed with each press, reducing the risk of error in dosing and ensuring consistency in treatment.
This transdermal gel should be applied on the skin directly over the area requiring treatment. Ensure that the area is clean and dry before application. Always follow the specific directions provided by your healthcare professional.
'Transdermal' refers to a method of delivering medication through the skin for systemic distribution. In the case of this gel, it means the active ingredients are absorbed through the skin into the body to provide pain relief.
Bupivacaine HCl is a local anesthetic. It is intended to numb the area of skin to which it is applied, thus reducing any associated pain or discomfort in that region.
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It is used to reduce inflammation and to relieve pain by reducing hormones that cause inflammation and pain in the body.
The percentages represent the concentration of each active ingredient in the transdermal gel. The Bupivacaine HCl is present at 0.5% and the Ketoprofen is incorporated at a concentration of 10%.
This product should be safe for most skin types. However, those with sensitive skin or certain skin conditions should consult a healthcare professional before use. If you experience any severe or persistent irritation, discontinue use and seek medical attention.
Before using this transdermal gel with other medications, consult with your healthcare provider to ensure that there are no potential interactions between medications.
The frequency of application depends on the specific treatment plan recommended by your healthcare provider. Always follow their instructions clearly and consult them with any questions or concerns.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
