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Clindamycin 1%/Tretinoin 0.025% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Tretinoin
Clindamycin Hydrochloride

Clindamycin 1%/Tretinoin 0.025% Topical Cream is a compounded medication designed to treat various skin conditions including Acne Vulgaris, Rosacea, Seborrheic Dermatitis, Perioral Dermatitis, and Melasma. This semisolid preparation, dispensed via a pump mechanism, combines two active ingredients to effectively reduce inflammation and clear up skin conditions. Its design ensures convenient and controlled application for localized treatment.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Tretinoin
Clindamycin Hydrochloride
Topical Cream
6427079ea64324023f51889d

Formula Information

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Clindamycin 1%/Tretinoin 0.025% Topical Cream is a compounded formulation designed to treat a variety of skin conditions. This medication combines the potent effects of two active ingredients, clindamycin and tretinoin. Clindamycin is an antibiotic that works by reducing the number of bacteria on the skin, while tretinoin is a retinoid that aids in reducing inflammation and promoting skin cell turnover.

The cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of the active ingredients, ensuring that the medication is applied directly to the affected area. It is typically used once or twice daily, or as directed by your healthcare provider.

While using Clindamycin 1%/Tretinoin 0.025% Topical Cream, some common side effects may include dryness, redness, and irritation of the skin. These are generally mild and temporary, but if you experience any severe side effects, it is crucial to contact your healthcare provider immediately. Always follow the instructions provided by your healthcare provider when using this medication to ensure its effectiveness and your safety.

However, it is important to remember that every individual's skin is unique, and results may vary. If you have any questions or concerns about this medication, or if you need further information, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to assist you with your healthcare needs.

Drug Interactions

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Clindamycin 1%/Tretinoin 0.025% Topical Cream is a compounded formulation designed for the treatment of acne vulgaris. This semisolid preparation is dispensed in a pump mechanism, ensuring a convenient and controlled application on the skin for localized treatment. The cream is a combination of two active ingredients, clindamycin and tretinoin, which work synergistically to reduce inflammation and the number of acne lesions.

Clindamycin, an antibiotic, works by inhibiting the growth of bacteria that contribute to acne. Tretinoin, on the other hand, helps to reduce the production of sebum, an oily substance that can clog pores and lead to acne. Together, these ingredients effectively reduce the number of acne lesions and improve the overall appearance of the skin.

Patients should be aware that this formulation may cause skin irritation, redness, and dryness. To mitigate these side effects, it is recommended to use a mild cleanser and moisturizer. Additionally, patients should avoid using other topical medications or products that may cause further irritation.

Increased sensitivity to the sun is another potential side effect of this combination of antibiotics. Therefore, patients are advised to use a sunscreen with an SPF of at least 30 and wear protective clothing when outdoors.

Prescribers should be aware of potential interactions between this topical cream and other medications, including oral antibiotics, antifungals, and other topical medications. Additionally, certain foods and beverages, such as dairy products, citrus fruits, and alcohol, may interact with this combination of antibiotics.

If you have any questions or concerns about the use of Clindamycin 1%/Tretinoin 0.025% Topical Cream, please do not hesitate to reach out for further information.

How Does it Work

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Clindamycin 1%/Tretinoin 0.025% Topical Cream is a compounded formulation designed to combat acne. This dual-action medication works by eliminating acne-causing bacteria and reducing the production of natural oils that can clog pores. Clindamycin, an antibiotic, halts the growth of bacteria, while Tretinoin, a derivative of vitamin A, aids in reducing inflammation and unclogging pores. The combined effect of these two active ingredients helps to decrease the number and severity of acne lesions.

The cream is dispensed in a pump mechanism, which is designed for convenient and controlled application on the skin. This ensures that the active ingredients are localized to the area of treatment, enhancing their effectiveness. It is crucial to follow the instructions provided by your healthcare provider when using this medication. Typically, the cream should be applied to the affected area once or twice daily, depending on the severity of the acne. Prior to application, cleanse the area with a mild cleanser. After applying the cream, wait at least 20 minutes before using any other topical medications or cosmetics.

While Clindamycin 1%/Tretinoin 0.025% Topical Cream is generally well-tolerated, it may cause skin irritation, redness, or dryness in some individuals. If you experience these or any other side effects, it is important to contact your healthcare provider. Additionally, while using this medication, it is advisable to avoid excessive sun exposure as it can increase the risk of sunburn.

If you have any questions or concerns about Clindamycin 1%/Tretinoin 0.025% Topical Cream, please do not hesitate to reach out to your healthcare provider or pharmacist.

Other Uses

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Clindamycin 1%/Tretinoin 0.025% Topical Cream is a compounded formulation that has been utilized off-label for the management of various skin conditions. These include actinic keratosis, a precancerous skin condition caused by excessive sun exposure; folliculitis, an inflammation of the hair follicles; and psoriasis, a chronic skin disease characterized by red, itchy, and scaly patches. This formulation has also been employed to address hyperpigmentation issues such as melasma, post-inflammatory hyperpigmentation, and lentigines, which are small tan, brown, or black spots on the skin. Furthermore, it has been used in the treatment of skin infections like impetigo, a highly contagious skin infection that causes sores and blisters. The cream has also been applied to reduce the appearance of wrinkles and fine lines, contributing to a more youthful appearance. It is crucial to understand that this formulation is not FDA-approved for any of these off-label uses. For any queries regarding the use of this formulation for any of these conditions, it is recommended to consult with a healthcare professional.

Frequently Asked Questions

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What is Clindamycin 1%/Tretinoin 0.025% Topical Cream?

This is a compounded formulation of two active ingredients, Clindamycin and Tretinoin, designed for topical application. Clindamycin is an antibiotic that prevents bacteria from growing on the skin, while Tretinoin is a form of vitamin A that helps the skin renew itself.

How is this cream dispensed?

The cream is dispensed in a pump mechanism, which allows for convenient and controlled application on the skin.

How should I use this cream?

Apply a thin layer of the cream to the affected area of the skin, usually once daily at bedtime or as directed by your doctor. Use a pea-sized amount for each application and gently rub it into the skin.

What is the purpose of the semisolid preparation?

The semisolid preparation is designed to facilitate localized treatment or absorption of the active ingredients into the skin. It ensures that the medication stays where it is applied and does not spread to other areas.

What conditions does this cream treat?

Clindamycin and Tretinoin topical cream is commonly used to treat acne. It may also be used to treat other skin conditions as determined by your healthcare provider.

What are the potential side effects of this cream?

Common side effects may include dryness, redness, peeling, or itching at the application site. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Can I use this cream if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. Tretinoin may be absorbed through the skin and could harm an unborn baby. It is not known whether Clindamycin and Tretinoin pass into breast milk.

Can I use other skincare products while using this cream?

Yes, but it's recommended to wait at least 20-30 minutes after applying the cream before applying other skincare products. This allows the medication to be fully absorbed into the skin.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Apply your next dose at the regular time. Do not double the dose to catch up.

How should I store this cream?

Store this medication at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clindamycin 1%/Tretinoin 0.025% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)