Check out our most popular compounded medications! Get Started
The Dehydroepiandrosterone 5 mg/Estradiol 0.5 mg/Estriol 2 mg/Progesterone 30 mg/Testosterone 1 mg/g Transdermal Gel is a compounded medication designed for the management of hormone-related conditions. This semisolid formulation is dispensed through a pump mechanism, which ensures easy and precise dosing. The gel is applied topically, allowing for direct absorption of the hormones into the bloodstream through the skin.
This transdermal gel is commonly used in the treatment of menopausal symptoms, such as hot flashes, night sweats, and vaginal dryness. It may also be prescribed for hormone replacement therapy in individuals with hormone deficiencies or imbalances. Additionally, this formulation can be used to address conditions like osteoporosis, certain types of amenorrhea, and to improve overall well-being in patients with low hormone levels.
By combining Dehydroepiandrosterone (DHEA), Estradiol, Estriol, Progesterone, and Testosterone in a single transdermal gel, this formulation provides a balanced approach to hormone therapy, targeting multiple symptoms and conditions with a synergistic effect. The gel consistency allows for a non-invasive and convenient application, making it a preferred choice for patients seeking an alternative to oral or injectable hormone therapies.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
The Dehydroepiandrosterone 5 mg/Estradiol 0.5 mg/Estriol 2 mg/Progesterone 30 mg/Testosterone 1 mg/g Transdermal Gel is a compounded medication designed to deliver a combination of hormones directly through the skin. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose with each use. The gel base allows for the hormones to be absorbed transdermally, offering an alternative route of administration for those who may not tolerate oral hormone therapies or for whom other routes are not recommended.
The combination of hormones in this formulation is often used in hormone replacement therapy (HRT) for individuals experiencing symptoms associated with menopause or andropause, or for those with hormone deficiencies or imbalances. Dehydroepiandrosterone (DHEA) is a precursor to sex hormones and is believed to have a role in improving mood and energy levels. Estradiol and estriol are forms of estrogen, which can alleviate menopausal symptoms such as hot flashes, vaginal dryness, and bone loss. Progesterone is included to counterbalance the effects of estrogen and reduce the risk of endometrial hyperplasia, while testosterone can help improve libido, muscle mass, and strength.
It is important for prescribers to consider the individual needs of the patient, as hormone therapy can be associated with risks and should be tailored to the lowest effective dose for the shortest duration necessary. Monitoring hormone levels and adjusting the dosage may be required to achieve optimal therapeutic outcomes and minimize side effects. Patients should be instructed on the proper application of the gel, which typically involves applying it to clean, dry skin on areas recommended by the healthcare provider, such as the inner arms or thighs, avoiding contact with eyes, and washing hands after application.
For patients and prescribers interested in using this transdermal hormone therapy, it is crucial to have a thorough understanding of the patient's medical history, current medications, and hormone levels. This personalized approach ensures that the therapy is appropriate and safe for the patient. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support and guidance to optimize patient care.
The transdermal gel formulation containing Dehydroepiandrosterone (DHEA), Estradiol, Estriol, Progesterone, and Testosterone is designed to deliver hormones directly through the skin into the bloodstream. This combination of hormones is often used in hormone replacement therapy (HRT) for the management of menopausal symptoms, such as hot flashes, vaginal dryness, and bone loss prevention. It may also be used for other hormone-related conditions as determined by a healthcare provider.
When considering the use of this transdermal gel, it is important to be aware of potential drug interactions. DHEA, Estradiol, Estriol, Progesterone, and Testosterone can interact with a variety of medications and substances, which may alter their effectiveness or increase the risk of adverse effects.
Estradiol and estriol, being estrogens, can interact with thyroid hormone replacement therapy, potentially necessitating an adjustment in the dose of thyroid medication. They may also reduce the clearance of drugs that are metabolized by cytochrome P450 enzymes, such as certain benzodiazepines, opioids, and anticoagulants like warfarin, leading to increased effects or side effects of these drugs. Concurrent use of estrogens with corticosteroids may result in increased corticosteroid effects due to decreased metabolism.
Progesterone can interact with benzodiazepines and other central nervous system depressants, potentially increasing their sedative effects. It may also affect the metabolism of certain cytochrome P450 substrates, including some anticonvulsants and antidepressants.
Testosterone may interact with oral anticoagulants, such as warfarin, increasing the risk of bleeding. It can also affect blood glucose levels, which may necessitate adjustments in antidiabetic medication for patients with diabetes. Additionally, testosterone may alter the effects of other hormones, particularly those used in HRT, such as estrogen and progesterone.
DHEA, as a precursor to testosterone and estrogen, may also interact with medications that affect hormone levels or are metabolized by similar pathways. It is important to monitor for signs of excessive androgenic effects, such as acne or hirsutism, or estrogenic effects, such as breast tenderness or uterine bleeding.
Patients should be advised to inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions. This includes over-the-counter drugs, as they can also interact with hormone therapy. Alcohol and tobacco use may also affect hormone levels and the effectiveness of this transdermal gel.
It is crucial to use this medication under the supervision of a healthcare provider who can monitor hormone levels and adjust the treatment as necessary. Regular follow-up appointments are important to assess the effectiveness of the therapy and to make any necessary adjustments to the treatment regimen.
If you have any questions or require further information regarding this formulation and its interactions with other drugs, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the support and information you need to safely and effectively use this medication.
The transdermal gel formulation containing Dehydroepiandrosterone (DHEA) 5 mg, Estradiol 0.5 mg, Estriol 2 mg, Progesterone 30 mg, and Testosterone 1 mg per gram is designed to deliver a combination of hormones directly through the skin into the bloodstream. This method of delivery is advantageous as it bypasses the gastrointestinal tract and liver, reducing the potential for metabolic breakdown of the hormones and avoiding first-pass metabolism, which can lead to a more consistent therapeutic effect.
DHEA is a precursor to both estrogen and testosterone and is involved in a wide array of physiological processes. Supplementation with DHEA in this gel can help restore levels that decrease with age, potentially improving mood, sexual function, and overall well-being. Estradiol and Estriol, both forms of estrogen, are critical for maintaining many aspects of female health, including bone density, skin integrity, and cardiovascular function. They can also alleviate symptoms of menopause such as hot flashes, vaginal dryness, and mood swings. Progesterone is another hormone that plays a key role in regulating menstruation and maintaining the early stages of pregnancy. It can also have a calming effect and contribute to the balance of hormone replacement therapy (HRT) by counteracting the proliferative effects of estrogen on the endometrium. Testosterone, while typically considered a male hormone, is also important in females for maintaining muscle mass, bone density, and sexual health. The inclusion of testosterone in this formulation can help address symptoms of testosterone deficiency such as fatigue, weight gain, and decreased libido.
This transdermal gel is particularly useful for patients who require a combination hormone therapy tailored to their specific needs. The semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise dosing. Patients are typically instructed to apply the gel to clean, dry skin on areas such as the arms, thighs, or abdomen. The hormones are then absorbed through the skin over time, providing a steady release into the bloodstream. This can lead to improved symptom control with potentially fewer side effects compared to oral hormone therapies.
It is important for both patients and prescribers to understand that this formulation is often part of a customized HRT regimen and should be used under the guidance of a healthcare professional with expertise in hormone replacement. Monitoring hormone levels and adjusting the dose as necessary is crucial to achieving the best therapeutic outcomes while minimizing the risk of adverse effects. If you have any questions or require further information about this formulation and its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide support and guidance.
This compounded transdermal gel is designed to deliver a combination of hormones directly through the skin for individuals who may benefit from hormone replacement therapy. It includes Dehydroepiandrosterone (DHEA), Estradiol, Estriol, Progesterone, and Testosterone, and can be used to address various conditions related to hormonal imbalances or deficiencies as advised by a healthcare professional.
The transdermal gel should be applied to clean, dry skin as directed by a healthcare professional. Typically, it's applied to areas of the skin with thin epidermis, such as the inner arms or thighs. The pump mechanism provides a measured dose with each depression, making it easy to apply the exact prescribed amount.
This gel is compounded for customized hormone replacement therapy and can be prescribed to both men and women, depending on their individual needs. However, it's crucial to follow a healthcare provider's instructions closely, as hormonal needs vary greatly between individuals.
The frequency of use for this transdermal gel will be determined by your healthcare provider based on your specific health needs and goals. It's essential to adhere to the prescribed regimen and not alter the dose without consulting your healthcare provider.
As with any medication, there may be side effects. Potential side effects can include skin irritation at the application site, hormonal imbalances, mood swings, and changes in libido. If you experience any adverse effects, contact your healthcare provider immediately.
It is recommended to apply the gel to areas as directed by your healthcare provider, typically where the skin is relatively thin and has good blood flow to facilitate absorption, such as the inner arms or thighs. Avoid applying it to areas with thick skin or areas that might be washed off easily such as hands.
If you miss a dose, apply the gel as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up without contacting your healthcare provider.
The onset of effect for the transdermal gel can vary depending on the individual and their specific health condition. Some may notice effects within a few days, while others may not observe changes for several weeks. Your healthcare provider can provide more specific timelines based on your treatment plan.
After applying the transdermal gel, it's essential to allow enough time for the medication to absorb into the skin before showering or swimming. Typically, waiting at least 1 hour is advised, but consult with your healthcare provider for specific instructions regarding your situation.
Store the compounded transdermal gel at room temperature, away from direct sunlight, heat, and moisture. Keep the pump tightly closed when not in use and keep it out of reach of children and pets. Always check with your compounding pharmacy or healthcare provider for any specific storage instructions.
Before using other topical products in conjunction with this transdermal gel, consult your healthcare provider. Some products may interfere with the absorption or effectiveness of the gel, or may increase the likelihood of skin irritation.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
